Prescription Required
Description
Drug Description:
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legitimate doctor’s prescription for every order of prescription Corlanor.
The manufacturer of Corlanor is Abbott and Lupin Limited.
Indications
Corlanor is a medication used to
- Treat adults who have chronic heart failure, with symptoms, to reduce their risk of hospitalization for worsening heart failure
- Treat certain children 6 months of age and older who have stable heart failure, with symptoms, that is due to an enlarged heart (dilated cardiomyopathy)
With chronic heart failure, your heart is unable to move enough oxygen-rich blood to the rest of your body and your heart might beat faster to keep up, which strains a weakened heart. Corlanor helps slow and regulate your heart rate.
Dosage and Administration
The dose of Corlanor will vary depending on the individual and severity of the condition being treated. It is important to follow your doctor’s instructions and take this medication exactly as prescribed to achieve best results.
Adult and pediatric patients weighing more than 40 kg
- Starting does is 2.5 or 5 mg twice daily with food; maximum dose is 7.5 mg twice daily
- After 2 weeks of treatment, dose is adjusted based on heart rate
Pediatric patients weighing less than 40 kg
- Starting dose is 0.05 mg/kg twice daily with food; maximum dose is 0.2 mg/kg (patients 6 months to less than 1 year) or 0.3 mg/kg (patients 1 year and older), up to at total of 7.5 mg twice daily
Corlanor comes as a tablet or oral solution and should be taken twice daily with food.
If you are prescribed Corlanor oral solution, see the Instructions for Use that comes with your medicine for important information about how to prepare and give or take the dose.
If you miss a dose of Corlanor, do not take another dose, but take the next dose at the usual time.
Side Effects
The most common side effects associated with Corlanorare:
- Increased blood pressure
Temporary brightness in part of your field of vision (usually caused by sudden changes in light ). This brightness usually occurs within the first 2 months of treatment with Corlanor and may go away during or after treatment.
Serious Side Effects
More serious adverse effects that may occur in adults and children when taking Corlanor, include the following:
- Increased risk of irregular or rapid heart rate (atrial fibrillation or hearth rhythm problems)
Tell your doctor if you have:
- Pounding or racing heart (palpitations)
- Chest pressure
- Worsened shortness of breath
- Near fainting or fainting
- Slower than normal heart rate
Tell your doctor if you have:
- A slowing heart rate
- Symptoms such as dizziness, fatigue, lack of energy
- In young children, signs and symptoms may include poor feeding, difficulty breathing, turning blue
- Harm to an unborn baby (fetal toxicity)
- Females who are able to get pregnant must use effective birth control during treatment with Corlanor
- Tell your doctor right away if you become pregnant during treatment with Corlanor
Allergic Reactions
Do not take Corlanor if you are allergic to ivabradine or any of the other listed tablet ingredients. If you experience any of the following signs of an allergic reaction, stop using this medication and call your doctor or get medical help:
- Hives
- Difficulty breathing
- Swelling of face, lips, tongue, or throat
Warnings and Precautions
Avoid drinking grapefruit juice during treatment because it can affect the way Corlanor works and may cause serious side effects. Be careful when driving or operating machinery where sudden changes in light can happen, especially when driving at night.
Do not take Corlanor if you have:
- Symptoms of heart failure that recently worsened
- Very low blood pressure
- Certain heart conditions like sick sinus syndrome, sinoatrial block, or 3rd degree atrioventricular block
- Slow resting heart rate before treatment with Corlanor
- Certain liver problems
Tell your doctor before breastfeeding while taking Corlanor. It is unclear whether ivabradine can pass into your breastmilk and cause harm to your nursing child.
Some drugs can interact with Corlanor and cause unwanted effects. Be sure to tell your doctor about all the medications you take, including over-the-counter medicines, and any of the following:
- John’s wort
- Rifampicin
- Barbiturates
- Phenytoin
- Certain antifungals
- Macrolide antibiotics (eg, clarithromycin)
- HIV protease inhibitors (nelfinavir)
- Nefadazone
- Diltiazem
- Verapamil
- Drugs that slow the heart rate (digoxin, amiodarone, beta blockers)
Form and Strength
This heart medication is available in tablet form.
Corlanor tablet strengths:
- 5mg
- 5mg
Bottles of 60 tablets
Corlanor oral solution is supplied as 5 mg/5 mL (1 mg/mL)
FAQs
What should I avoid while taking Corlanor?
You should avoid drinking grapefruit juice and taking St. John’s wort while taking Corlanor because there is a potential for these to interact with Corlanor and cause unwanted effects.
Why is it necessary to take Corlanor with food?
Administraion of Corlanor with food is recommended because it delays absorption by about 1 hour and increases plasma exposure by 20% to 40%.
