Indications 

Norethindrone/Ethinyl Estradiol combination is primarily used to prevent pregnancy. It contains two hormones, a progestin (norethindrone) and an estrogen (ethinyl estradiol). 

Brevicon 28-day works by preventing ovulation, thickening cervical mucus to hinder sperm movement, and thinning the lining of the uterus to prevent implantation. It changes the lining of the uterus, making it less receptive to the implantation of a fertilized egg. 

Use and Dosage 

Brevicon 28-day comes in the form of tablet to take by mouth as directed by your doctor, usually once daily. Pick a time of day that is easy for you to remember and take your pill at the same time each day. Swallow the tablet whole with a glass of water. Chewing the tablet may affect the taste and texture, but it does not impact the effectiveness of the medication.  

Brevicon 28-day comes in a packet of 28 pills. The first 28 pills are active pills that contain hormones, and the remaining 7 pills are inactive pills (placebos) that do not contain hormones. You take one active pill at the same time every day for 28 days, followed by one inactive pill for the next 7 days. This cycle is then repeated with a new pack. 

If you miss an active pill, take it as soon as you remember, even if it means taking two pills in one day. If you miss two or more active pills in a row, use backup contraception (such as condoms) and consult the package insert or your healthcare provider for instructions on what to do. 

Side Effects 

Common Side Effects 

• Acne 
• Bloating, fluid retention 
• Breast pain, tenderness, or swelling 
• Brown, blotchy spots on exposed skin 
• Changes in appetite 
• Discomfort wearing contact lenses 
• Dizziness 
• Gain or loss of body or facial hair 
• Increased or decreased interest in sexual activity 
• Irritability 
• Nausea 
• Vaginal discharge 
• Vomiting 
• Weight gain or loss 

Serious Side Effects 

• Abdominal or stomach pain 
• Breakthrough bleeding or spotting between periods 
• Breast lumps 
• Changes in hearing 
• Changes in sleep 
• Changes in weight 
• Confusion 
• Dark urine 
• Decreased bleeding during periods 
• Decreased interest in activities 
• Diarrhea 
• Excessive eating 
• Fever 
• Frequent urination 
• Headaches or migraines 
• Increased blood pressure 
• Increased thirst 
• Infections 
• Joint pain 
• Loss of appetite 
• Low back or flank pain 
• Muscle aches 
• Nausea 
• Pain and numbness 
• Pain when urinating 
• Pale stools 
• Poor concentration 
• Poor wound healing 
• Prolonged bleeding at periods 
• Skin rash 
• Swelling of the feet, ankles, or lower leg 
• Thoughts of suicide 
• Unexplained weight loss 
• Urinating more often than usual 
• Vision changes 
• Vomiting 
• Weight loss 
• Yellowing of the skin or whites of the eyes 

Cautions 

• Brevicon 28-day is not recommended for use in women who have not yet started menstruating or have reached menopause. The appropriate age range for the use of Brevicon may vary depending on individual circumstances and consult with a healthcare provider. 
• The combination of Norethindrone/Ethinyl Estradiol is most effective in preventing pregnancy when taken consistently and at the same time every day. Missing doses or not following the prescribed instructions may decrease its effectiveness. 
• Brevicon 28-day may not be suitable for everyone. Discuss any pre-existing medical conditions you have with your healthcare provider, as certain conditions may increase the risk of complications or make Brevicon 28-day less suitable for you. Examples include a history of blood clots, certain types of cancers, liver disease, or uncontrolled high blood pressure. 
• The combinations of Norethindrone/Ethinyl Estradiol should not be taken if you are pregnant or suspect you may be pregnant. Discontinue and consult with your healthcare provider if you become pregnant while taking the medication. 
• Brevicon can increase the risk of blood clots, especially in individuals with a history of blood clotting disorders or a family history of such conditions.  
• Brevicon can interact with certain medications, including some antibiotics, antiviral drugs, anticonvulsants, and herbal supplements. These interactions can affect the effectiveness of the contraceptive or increase the risk of side effects. 
• Smoking while taking Brevicon 28-day can increase the risk of serious cardiovascular side effects, such as blood clots, heart attack, or stroke. Smoking while using hormonal contraceptives. 
• Some individuals may be allergic to the ingredients in Brevicon 28-day. If you have a known allergy to norethindrone, ethinyl estradiol, or any other components of the medication, avoid taking it and inform your healthcare provider. 
• The hormones in Brevicon 28-day may pass into breast milk and potentially affect the nursing infant. Discuss the use of Brevicon while breastfeeding with your healthcare provider to determine the most suitable contraceptive options.