Nystatin Vaginal Cream (Nystatin) Medication

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Drug Description


This medication is prescribed for the treatment of vaginal fungal infections, commonly referred to as vaginal yeast infections. Its therapeutic action mitigates symptoms such as itchiness, redness, and troublesome discharge. Nystatin achieves its efficacy by inhibiting the proliferation of the fungal organism. 

Uses and Dosage 

This product is intended for vaginal administration. Adhere to proper hygiene by ensuring clean hands prior to use. Utilize the applicator, filling it with the prescribed amount of cream as indicated. Insert the applicator deeply into the vaginal canal, and subsequently depress the plunger to dispense the medication. Follow the dosing regimen as instructed by your healthcare provider, typically administered once daily at bedtime, or twice daily in the morning and evening. If the applicator is designed for multiple uses, consult the product guidelines for instructions on cleaning. 

To prevent the inadvertent leakage of medication from the vaginal cavity, recline as soon as possible post-application. Consider employing a sanitary napkin to prevent any potential staining of clothing. Refrain from using tampons while under this medication’s course, as they may compromise its efficacy. In most circumstances, avoid the use of medicated douches during nystatin treatment. Should you have any inquiries, do not hesitate to consult your doctor or pharmacist. 

For optimal therapeutic outcomes, ensure consistent and punctual use of this medication, adhering to the same daily time(s) for administration.  

Side Effects 

Common Side Effects

Nystatin may cause several potential side effects at the application site, including but not limited to:  

  • Nausea 
  • Vomiting 
  • Diarrhea 
  • Stomach discomfort 
  • Burning sensation 
  • Itching 
  • Rashes 
  • Localized pain  

Severe Side Effects

Certain adverse reactions necessitate immediate medical attention. If you encounter any of the ensuing symptoms, promptly notify your healthcare provider: 

  • Development of rashes 
  • Breathlessness 
  • Swelling of the face, eyes, or mouth 
  • Appearance of rashes accompanied by skin peeling or blistering of the lips, mouth, or eyes, coupled with the presence of fever 

Inform your healthcare provider if any of these side effects persist, become particularly severe, or if you encounter other unanticipated adverse reactions during the course of treatment. 


Prior to initiating the use of nystatin, communicate with your healthcare provider or pharmacist regarding any known allergies, including allergies to nystatin itself or any other allergens. This product may comprise inactive components that possess the potential to trigger allergic reactions or other adverse reactions. Should you require additional information, do not hesitate to consult your pharmacist. 

Furthermore, disclose your medical history to your healthcare provider or pharmacist before commencing this medication. 

Exercise caution when considering the use of this medication during pregnancy and only proceed when its necessity is unequivocal. If you are currently pregnant or suspect that you may be, consult your doctor before utilizing the applicator. Engage in a comprehensive discussion with your healthcare provider regarding the associated risks and benefits in your specific circumstance. 

Additional information

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Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Nystatin Vaginal Cream (Nystatin). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Nystatin Vaginal Cream (Nystatin).