Vemlidy (Tenofovir alafenamide) Medication


Vemlidy (Tenofovir alafenamide)

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Drug Description


Vemlidy is a prescribed medication for adults with stable (compensated) liver disease to manage chronic hepatitis B virus (HBV) infection. 

Classified as a nucleoside reverse transcriptase inhibitor (NRTI), Vemlidy works by inhibiting the replication of the hepatitis B virus within the body. This action may lead to a reduction in HBV levels and potential liver improvement. 

Uses and Dosage 

Before starting Vemlidy treatment, HIV-1 testing is essential, as this medication should not be used as a standalone therapy for patients with HIV-1 infection. 

Review the medication guide and patient information leaflet of Vemlidy before taking it and with every prescription refill. For any inquiries, consult your doctor or pharmacist. 

The dosage of this medication is determined based on the patient’s medical condition, treatment response, and concurrent medications. 

Typically, Vemlidy is taken once daily with food as prescribed by the doctor. 

Patients receiving dialysis should take Vemlidy following their dialysis sessions. Maintaining a regular dosing routine is essential to ensure no doses are skipped. 

If vomiting happens within 1 hour after a dose, take an additional dose. If vomiting occurs more than 1 hour after the dose, do not take an extra dose; instead, adhere to your regular dosing schedule for the next dose. 

Adhere strictly to the prescribed dosage of Vemlidy and refrain from altering it, discontinuing, or deviating from the treatment plan unless specifically instructed by your doctor. Such actions could exacerbate the infection, increase resistance, or intensify side effects. 

Side Effects 

Listed below are the potential adverse effects of Vemlidy. Inform your doctor right away if any of these symptoms last or worsen. 

Common Side Effects 

  • Abdominal discomfort, nausea, vomiting, diarrhea 
  • Elevated body temperature, pain 
  • Fatigue, dizziness 
  • Headache 
  • Depressed mood 
  • Itching, skin rash 
  • Sleep disturbances (insomnia) 

Serious Side Effects 

  • Sore throat, flu-like symptoms, increased bruising, or abnormal bleeding 
  • Kidney problems: 
    • Little or no urination 
    • Painful or difficult urination 
    • Swelling in the feet or ankles 
    • Fatigue 
    • Breathlessness 
  • Liver problems:  
    • Abdominal swelling 
    • Upper stomach pain 
    • Fatigue 
    • Loss of appetite 
    • Dark urine 
    • Pale stools 
    • Jaundice (yellowing of the skin or eyes) 

Inform your doctor right away if you experience any of the serious side effects mentioned above. 

Progressive exacerbation of mild lactic acidosis symptoms is possible, and this condition carries the potential for fatality. Seek immediate medical assistance for the following symptoms:  

  • Atypical muscle pain 
  • Respiratory difficulties 
  • Abdominal pain 
  • Vomiting 
  • Rapid/slow/irregular heartbeats 
  • Dizziness 
  • Sensation of cold 
  • Extreme weakness or profound fatigue 

Vemlidy may affect the immune system, even after weeks or months of use. Notify your healthcare provider if you experience: 

  • Indications of a new infection: 
    • Fever 
    • Night sweats 
    • Swollen glands 
    • Cold sores 
    • Cough 
    • Wheezing 
    • Diarrhea 
    • Unexplained weight loss 
  • Difficulty in speech or swallowing, issues with balance or eye coordination, or sensations of weakness or tingling 
  • Swelling in the neck or throat (enlarged thyroid), alterations in menstrual patterns, or erectile dysfunction 

Allergic Reactions 

Although rare, a severe allergic reaction to Vemlidy may occur. Prompt medical attention is required upon noticing any signs of an allergic reaction, such as: 

  • Hives 
  • Troubled breathing 
  • Face, lips, tongue, or throat swelling 

Not all side effects of Vemlidy are included in this list. Report to your doctor if any unlisted effects occur. 


Before taking Vemlidy, inform your doctor if you have any known allergies, particularly to tenofovir alafenamide.  

This medicine may contain inactive ingredients that can potentially trigger allergic reactions or other complications. For further details, consult with your pharmacist. 

To ensure Vemlidy is safe for you, disclose to your physician your medical background, especially if you have a history of: 

  • Renal complications 
  • HIV infection 
  • Other hepatic issues (e.g., hepatitis C, cirrhosis) 
  • Bone disorders (e.g., bone disease, osteoporosis, fractures) 
  • Pancreatitis 

Inform your healthcare providers about all your medications, including prescriptions, over-the-counter drugs, vitamins, and herbal products, to avoid potential drug interactions with Vemlidy. 

Some of the products that could interact with Vemlidy include: 

  • Adefovir  
  • Orlistat 
  • Other medications with potential kidney-related effects, such as aminoglycosides like amikacin and gentamicin 

Avoid concomitant usage of Vemlidy with other products containing tenofovir. 

After discontinuing Vemlidy, individuals with a history of hepatitis B may experience a recurrence or exacerbation of the condition. Regular liver function tests are recommended during and post-treatment for an extended period. 

The potential effects of Vemlidy on an unborn baby are uncertain. Inform your doctor if you become pregnant while taking this medication. 

Consult your doctor regarding the safety of breastfeeding while taking Vemlidy, as it may pose potential risks. 

Additional information

Generic name:

Tenofovir alafenamide





Quantities Available:

30, 90

Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Vemlidy (Tenofovir alafenamide). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Vemlidy (Tenofovir alafenamide).