Analpram HC Cream (Pramoxine/HC) Medication


Analpram HC Cream (Pramoxine/HC)

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Analpram HC Cream is a prescription medicine used for alleviating itching and inflammation stemming from various skin conditions, including allergic reactions, eczema, minor burns, and insect bites. 

Furthermore, Analpram HC Cream is effective in addressing itching or swelling associated with hemorrhoids or inflammatory conditions of the rectum or anus. 

Analpram HC Cream is a combination of pramoxine, a corticosteroid, and hydrocortisone, an anesthetic or numbing agent. Pramoxine works by disrupting pain signals transmitted from nerves to the brain, while hydrocortisone diminishes the activity of inflammation-inducing chemicals in the body. 

Uses and Dosage 

Before using Analpram HC Cream and with every prescription refill, thoroughly review the accompanying medication guide and patient information leaflet. Seek guidance from your doctor or pharmacist for any queries or uncertainties. 

Analpram HC Cream should be applied exclusively to the skin as directed by the doctor. Prevent contact with the eyes, nose, ears, or mouth; if contact occurs, promptly rinse the affected area with plenty of water.  

Analpram HC Cream intended for rectal use should only be used for rectal application. 

Typically, Analpram HC Cream is applied to the affected area 3 to 4 times daily, depending on the severity of the condition.  

For skin application, follow these steps: 

  1. Prior to application, wash and dry your hands. 
  2. Thoroughly cleanse and dry the affected skin area. 
  3. Apply a small quantity of the cream to the affected area and gently massage it into the skin. 
    • Unless directed by your doctor, refrain from covering the treated skin area. 
  4. After applying the cream, wash your hands unless you are using it to treat a hand condition. 

For rectal application, follow these steps: 

  1. The use of this cream is advisable after a bowel movement. 
  2. Begin by cleaning the affected area with mild soap and water, ensuring thorough rinsing and gentle patting dry. 
  3. To treat the external anal area, apply a small amount of the cream to the affected region and gently rub it in. 
  4. For internal application, use the applicator tip, following package instructions or your doctor’s guidance. Fill the applicator as directed. 
  5. Carefully insert the applicator tip only 1/2 to 1 inch (1.5 to 2.5 centimeters) into the anus and apply as instructed in and around the anal opening.  
    • Do not insert your finger or any part of the container into the anus and avoid going beyond 1/2 to 1 inch (1.5 to 2.5 centimeters) with the applicator tip.  
    • Never use your finger to apply the medication internally. 
    • Unless directed by your doctor, avoid using plastic or waterproof bandages to cover the area. 
  6. After use, wipe the applicator with a tissue and replace its cover. 
  7. Immediately wash your hands after application. 

For optimal outcomes, use Analpram HC Cream regularly, exactly as directed at the same time each day. Refrain from exceeding the prescribed dosage, frequency, or duration of treatment advised by your doctor. 

Notify your doctor if your condition does not improve or deteriorate within 1 to 2 weeks. 

Side Effects 

Listed below are the potential adverse effects of Analpram HC Cream. Tell your doctor promptly if any of these symptoms continue or worsen. 

Common Side Effects 

  • Slight redness or swelling on the treated skin 
  • Thinning of the skin where the cream is applied 
  • Numbness in areas where the cream is accidentally used 

Serious Side Effects 

  • Signs of excessive skin absorption, including: 
    • Blurred vision, eye discomfort, or seeing halos around lights 
    • Mood alterations 
    • Sleep disturbances (insomnia) 
    • Elevated blood sugar levels (increased thirst or urination, hunger, dry mouth, fruity breath odor, weight loss) 
    • Weight gain and facial puffiness 
    • Muscle weakness and persistent fatigue 
  • Rectal bleeding or severe irritation in any treated skin 

Discontinue Analpram HC Cream use and promptly contact your doctor if you exhibit the serious side effects above. 

Allergic Reactions 

In rare cases, Analpram HC Cream may trigger a serious allergic response. Seek medical aid without delay if any signs of an allergic reaction manifest, such as: 

  • Hives 
  • Itching/swelling (especially of the face/lips//tongue/throat) 
  • Trouble breathing 

This list does not cover all side effects of Analpram HC Cream. Consult your doctor if you experience any unexpected effects while using this cream. 


Before starting treatment with Analpram HC Cream, inform your doctor if you have any known allergies, particularly to pramoxine or hydrocortisone. 

Ask your pharmacist for more details about this cream, as it could contain inactive ingredients that may cause allergic reactions or other adverse effects. 

To ensure Analpram HC Cream is safe for you, disclose to your doctor your medical background, especially if you have a history of: 

  • Liver condition 
  • Diabetes 
  • Ocular issues 
  • Gastrointestinal disorder 
  • Rectal sore or infection 
  • Or if you use immunosuppressive drugs, including steroids 

The likelihood of interaction between Analpram HC Cream and oral or injected medications is low, but it should be noted that drug interactions can still occur. To mitigate any potential risks, disclose your entire medication usage, including prescription drugs, over-the-counter medications, vitamins, and herbal products to all healthcare providers involved in your care. 

Analpram HC Cream is ineffective against bacterial, fungal, or viral skin infections. Do not use this cream if you have a skin infection; first, seek treatment until the infection has resolved. 

In rare cases, prolonged usage of Analpram HC Cream may temporarily impact a child’s growth. Scheduling regular appointments with a doctor to accurately assess your child’s height is recommended. 

The potential impact of Analpram HC Cream on an unborn baby is uncertain. If you are pregnant or intend to become pregnant while using this cream, inform your healthcare provider. 

The transfer of hydrocortisone and pramoxine into breast milk and their potential effects on a nursing infant remain uncertain. If you are breastfeeding, discuss the use of this cream with your healthcare provider. 

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Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Analpram HC Cream (Pramoxine/HC). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Analpram HC Cream (Pramoxine/HC).