Indications 

Axid is a prescription medication used for: 

• Treating active duodenal ulcers. 
• Providing maintenance therapy to duodenal ulcer patients with a reduced dosage of 150 mg h.s. following the resolution of an active duodenal ulcer. 
• Treating endoscopically identified esophagitis, including ulcerative and erosive esophagitis and heartburn associated with gastroesophageal reflux disease (GERD). 
• Treating active benign gastric ulcers. 

Axid is classified as an H2 blocker and functions by reducing the production of stomach acid. This mechanism of action facilitates the alleviation of various symptoms, such as persistent cough, stomach pain, heartburn, and difficulty swallowing. 

Uses and Dosage 

Before taking Axid and every time you get a refill, carefully read its medication guide and patient information leaflet. Do not hesitate to consult your doctor or pharmacist with any questions or concerns. 

The dosage and length of treatment with Axid may vary per individual based on their medical condition and response to the treatment.  

Typically, Axid is taken once daily at bedtime or twice a day as prescribed by the doctor, without regard to food intake. 

For optimal efficacy, take Axid regularly at consistent time intervals. Avoid exceeding the prescribed dose or frequency of use, as this will not hasten improvement and may heighten the risk of adverse effects.  

Continue taking Axid for the prescribed duration of treatment, regardless of symptom improvement. Inform your physician if there is no improvement or a decline in your medical condition. 

Side Effects 

Listed below are the side effects associated with the use of Axid. If any of them last or worsen, tell your doctor promptly. 

Common Side Effects 

• Dizziness 
• Headache 
• Diarrhea 

Children may also experience common side effects such as: 

• Nose or throat irritation 
• Throwing up 
• Feeling irritable 
• Stuffy nose 
• Cough 

Serious Side Effects 

• Any unexplained bruising or bleeding 
• Fever 

Call your doctor immediately if you experience any of the above-mentioned severe side effects. 

Allergic Reactions 

A severe allergic reaction to Axid is uncommon. However, seek emergency medical attention if you exhibit signs of an allergic reaction, such as: 

• Rash 
• Hives 
• Itching 
• Red, swollen, blistered, or peeling skin, with or without fever 
• Wheezing 
• Tightness in the chest or throat 
• Difficulty breathing, swallowing, or talking 
• Unusual hoarseness 
• Mouth, face, lips, tongue, or throat swelling 

This list does not contain all the potential side effects of Axid. Tell your doctor if other side effects not listed above are experienced. 

Cautions 

Before taking Axid, inform your doctor and pharmacist if you have any known hypersensitivities, especially to: 

• Nizatidine 
• Other H2 blockers (e.g., cimetidine, famotidine, ranitidine) 
• Other medications 
• Any ingredients present in Axid capsules 

Before starting treatment with Axid, disclose your medical history to your doctor, especially of:  

• Immune system problems 
• Kidney problems 
• Liver problems 
• Certain lung diseases (e.g., COPD) 
• Other stomach problems (e.g., tumors) 

Inform your physician about all the medicines you are taking, including prescription and over-the-counter drugs, dietary supplements, and herbal products, to minimize the possibility of drug interactions that could impact Axid’s efficacy or raise the likelihood of adverse effects. 

Axid reduces stomach acid, which may impact the effectiveness of certain products that require stomach acid for proper absorption. Such products include: 

• Atazanavir 
• Dasatinib 
• Certain azole antifungals (e.g., itraconazole, ketoconazole) 
• Levoketoconazole 
• Pazopanib 
• Sparsentan 
• Others 

The use of Axid can affect certain laboratory tests, including urine protein tests, resulting in inaccurate test outcomes. Inform all medical professionals and laboratory staff that you are taking this medication. 

The use of Axid during pregnancy is advised only if deemed necessary. Consult your doctor to assess the potential risks and benefits before proceeding. 

Nizatidine is transferred into breast milk. Before breastfeeding, consult with your doctor.