Bactroban Cream (Mupirocin) Medication


Bactroban Cream (Mupirocin)

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Drug Description


Bactroban Cream is a prescription medication used to treat secondarily infected skin lesions caused by susceptible isolates of staphylococcus aureus (s. aureus) and streptococcus pyogenes (s. pyogenes). 

The active ingredient in Bactroban Cream is mupirocin, which is a special kind of antimicrobial agent that works by stopping the growth of bacteria. It does this by blocking the production of proteins and RNA in the bacteria through reversible inhibition of isoleucyl-transfer RNA. 

Uses and Dosage 

Before using Bactroban Cream and with each prescription refill, thoroughly review its medication guide and patient information leaflet. Seek the guidance of your doctor or pharmacist for any questions or concerns. 

Bactroban Cream is indicated for topical use only and should not come into contact with mucosal surfaces such as the eyes, nose, mouth, or vagina. 

The usual regimen for Bactroban Cream involves a thrice-daily application for 10 days.  

To apply the cream: 

  1. Wash hands before application. 
  2. Clean and dry the affected area. 
  3. Apply a small amount of cream to the affected area using a cotton swab or gauze pad. (Avoid spreading the cream over extensive skin surfaces) 
  4. You may cover the treated area with a clean gauze pad following the application of the cream unless otherwise instructed by your healthcare provider. 
  5. Wash hands after each application. 

To maximize the therapeutic benefits of Bactroban Cream, adhere to a consistent usage routine for the full prescribed duration, regardless of symptom alleviation within a few days. Premature cessation of treatment may lead to a resurgence of the infection. 

Notify your doctor if your condition fails to improve within 3 to 5 days. 

Side Effects 

Listed below are the side effects associated with the use of Bactroban Cream. If any of them persist or worsen, inform your doctor immediately. 

Common Side Effects 

  • Burning sensation 
  • Stinging sensation 
  • Itching 
  • Pain 

Serious Side Effects 

  • Severe stomach pain 
  • Watery or bloody diarrhea 
  • Severe itching 
  • Rash 
  • Irritation of treated skin 
  • Unusual skin blistering or peeling 
  • Signs of a new skin infection 

Seek medical assistance immediately if you experience any of the serious symptoms mentioned above. 

Allergic Reactions 

In rare cases, Bactroban Cream may cause a severe allergic reaction. Seek immediate medical attention if you experience symptoms such as: 

  • Hives 
  • Dizziness 
  • Fast or pounding heartbeats 
  • Wheezing 
  • Difficult breathing 
  • Face, lips, tongue, or throat swelling 

This list does not contain all the potential side effects of Bactroban Cream. Inform your doctor if other side effects not listed above are experienced. 


Before using Bactroban Cream, inform your doctor and pharmacist if you have any known hypersensitivities, especially to mupirocin, other medicines, or any ingredients present in this cream. 

To ensure Bactroban Cream is safe for you, disclose to your physician your medical background, specifically regarding any history of kidney disease. 

To reduce the risk of adverse effects or drug interactions that may affect the effectiveness of Bactroban Cream, inform your doctor and pharmacist about all medications, including prescription and over-the-counter drugs, dietary supplements, and herbal products that you are currently taking. 

The use of Bactroban Cream can result in a type of diarrhea known as clostridium difficile-associated diarrhea (CDAD). CDAD severity can vary from mild diarrhea to fatal colitis. If diarrhea occurs while using or after stopping Bactroban Cream, immediately contact a healthcare provider or seek emergency medical attention. 

Bactroban Cream should be used during pregnancy only when necessary. Discuss the potential risks and benefits with a doctor prior to use. 

Consult with your doctor before using Bactroban Cream while breastfeeding since it is unclear whether mupirocin is excreted in human milk. If your doctor approves of breastfeeding and you are using the cream on your breast or nipple, ensure to wash the area well before nursing. 

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Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Bactroban Cream (Mupirocin). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Bactroban Cream (Mupirocin).