Ciprodex (Ciprofloxacin hcl/dexamethasone) Medication


Ciprodex (Ciprofloxacin hcl/dexamethasone)

Prescription Prescription Required
Buy Brand
Dosage Quantity Buy Now
0.3/0.1% Add To Cart

Generic Alternative - Ciprodex (Ciprofloxacin hcl/dexamethasone)

Prescription Prescription Required
Buy Ciprofloxacin hcl/dexamethasone
Dosage Quantity Buy Now
0.3/0.1% Add To Cart
5 Star Excellence award from Shopper Approved for collecting at least 100 5 star reviews



Ciprodex is an otic solution prescribed to treat bacterial ear infections such as middle ear infections in children with ear tubes (also called otitis media) and outer ear infections (also called otitis externa) in people six months of age and older. 

Ciprodex utilizes the synergistic combination of two active ingredients: 

  • Ciprofloxacin – a quinolone-type antibiotic that exerts its bactericidal effect by inhibiting the synthesis of bacterial proteins, thereby disrupting the ability of bacteria to multiply and survive. 
  • Dexamethasone – an anti-inflammatory corticosteroid that suppresses the action of chemical mediators that contribute to the inflammatory response. 

Together, these two active ingredients provide a comprehensive approach to treating bacterial ear infections, addressing the causative bacterial agents and the associated inflammation. 

Ciprodex will only work on bacterial ear infections and will not be effective for other types of ear infections. The indiscriminate or excessive use of this antibiotic may result in decreased efficacy due to the development of antibiotic resistance. 

Uses and Dosage 

Prior to initiation of treatment with Ciprodex and with each refill, thoroughly review its accompanying medication guide and patient information leaflet. Clarify any questions or concerns to a healthcare provider or pharmacist to fully understand this medication, including potential risks and benefits. 

Ciprodex is a liquid suspension intended for administration into the ear, with a recommended dose of four drops twice daily for seven consecutive days in the morning and evening. 

Use Ciprodex precisely as directed, especially when prescribed differently from what is listed here.  

Prior to use, ensure that ear canals are clean and dry. For accurate administration and to avoid contamination, have someone else administer the drops.  

To use the eardrops, follow these steps: 

  1. Warm the solution by holding the bottle in your hand for one or two minutes. 
  2. Shake the bottle well. 
  3. Lie down with the affected ear facing upward. 
  4. Administer the prescribed number of drops into the ear. 
  5. Avoid touching the tip of the bottle with your ear, fingers, or any other surface. 
  6. For middle ear infections, gently push the tragus (the small flap of cartilage in front of the ear canal near the face) inward five times to allow the drops to reach the middle ear. 
  7. Remain in the lying position with the affected ear upward for 60 seconds. 
  8. Repeat the steps for the opposite ear if necessary. 

For optimal results, consistently use Ciprodex at designated times every day. Continue usage for the entire prescribed duration, even if symptoms subside prematurely. Premature cessation of this medication may lead to bacterial proliferation, potentially causing a recurrence of the infection. 

If there is no improvement in your symptoms after seven days of treatment or if new symptoms arise, contact your physician immediately. 

Side Effects 

Possible adverse reactions that may occur during treatment with Ciprodex are listed below. If any of these side effects persist or worsen, seek medical attention immediately. 

Common Side Effects 

  • Itching or pain in the ear 
  • Discomfort or fullness in the ear 
  • Unusual taste in the mouth 
  • Irritability 
  • Buildup of debris in the ear canal 

Serious Side Effects  

  • Drainage from the ears 
  • Severe burning or intense irritation after using ear drops. 

Get medical help immediately if you experience any of the symptoms listed above. 

Allergic Reactions 

Although rare, severe allergic reactions can occur with the use of Ciprodex. Seek medical assistance immediately in the event of the following symptoms: 

  • Rash 
  • Itching or swelling of the face, tongue, or throat 
  • Severe dizziness 
  • Trouble breathing 

The above-listed adverse reactions are not exhaustive, and it is possible to experience other symptoms while taking Ciprodex. For any concerning side effects, seek the advice of a healthcare provider. 


Prior to utilizing Ciprodex, inform your physician or pharmacist about any allergies to ciprofloxacin or dexamethasone, or quinolone antibiotics such as levofloxacin, and other potential allergies.  

This ear drop medication may contain inactive ingredients, including preservatives such as benzalkonium chloride, which can cause allergic reactions or other issues. For further information, consult your pharmacist. 

Tell your doctor about all other medications, including prescription/nonprescription drugs, supplements, and herbal products, to prevent drug interactions. 

Disclose your medical history to your doctor, especially ear infections caused by a fungus or virus (such as herpes simplex). 

To avoid complications, infected ears should be protected from exposure to water, including during bathing. Swimming should be avoided unless instructed otherwise by a physician. 

Additional information

Generic name:

Ciprofloxacin hcl/dexamethasone


Drops, Otic Suspension



Quantities Available:

7.5mL, 10mL, 15mL

Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Ciprodex (Ciprofloxacin hcl/dexamethasone). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Ciprodex (Ciprofloxacin hcl/dexamethasone).