Indications 

Cleocin is a prescription medication intended to treat serious infections caused by susceptible anaerobic bacteria, such as infections of the lungs, skin, blood, female reproductive organs, and internal organs. 

As a lincomycin antibiotic, Cleocin exerts its bacteriostatic effect by inhibiting bacterial growth and proliferation. This antibiotic may be used as a monotherapy or in combination with other medications under a licensed healthcare provider’s guidance. 

Cleocin can also be used to treat severe infections caused by susceptible strains of streptococci, pneumococci, and staphylococci. This medication should be reserved for patients allergic to penicillin or for those for whom penicillin is deemed inappropriate by the treating physician. 

This antibiotic will not work on viral infections such as colds and flu. Use only when prescribed by a qualified medical practitioner to avoid an elevated risk of contracting future infections resistant to antibiotic treatment. 

Uses and Dosage 

Before treatment with Cleocin, carefully review its medication guide and patient information leaflet. Clarify any questions or concerns to your physician or pharmacist for better understanding, especially its risks, and benefits. 

The appropriate dosage and length of intake of Cleocin are determined by the individual’s medical condition and response to treatment. For children, weight is also considered when determining the optimal dose. 

Cleocin should be taken orally, without regard to food, typically four times daily (every six hours) or as prescribed by your doctor.  

To prevent throat irritation, take Cleocin with a full glass of water (8 ounces or 240 milliliters). After taking this medication, allow at least 10 minutes before lying down. 

For optimal results, Cleocin should be taken at the same time(s) every day. Continue to take the entire prescription even if you feel better. Stopping too soon or skipping doses may cause a recurrence of infection and bacterial resistance.  

Side Effects 

Possible adverse reactions that may occur during treatment with Cleocin are listed below. If any of them persist or worsen, seek medical attention immediately. 

Common Side Effects 

• Nausea 
• Vomiting 
• Stomach pain 
• Mild skin rash 
• Vaginal itching or discharge 

Serious Side Effects  

• Changes in bowel habits 
• Severe stomach pain 
• Watery or bloody diarrhea 
• Little to no urination 

Get immediate medical attention if any of the above severe symptoms are experienced. 

Allergic Reactions 

Rarely, Cleocin may cause severe allergic reactions. Get emergency medical help if you observe the following symptoms: 

• Rash 
• Itching or swelling of the face, tongue, or throat 
• Severe dizziness 
• Trouble breathing 

The above-listed adverse reactions are not the complete list. For any bothersome unlisted side effects, consult your doctor. 

Cautions 

Prior to Cleocin treatment, inform your doctor or pharmacist of any previous allergic reactions to clindamycin, lincomycin, or other allergens.  

This medication may include inactive ingredients that could result in allergic reactions or other complications. For additional information, kindly consult with your pharmacist. 

To avoid drug interactions, inform your healthcare providers about all prescription and nonprescription drugs, vitamins, dietary supplements, and herbal products that you are currently using or planning to use. 

Specifically mention any of the following medications:  

• Clarithromycin (Biaxin, in PrevPac) 
• Erythromycin (E.E.S, E-Mycin, Erythrocin, others) 
• Indinavir (Crixivan) 
• Itraconazole (Sporanox) 
• Ketoconazole (Nizoral) 
• Nefazodone 
• Nelfinavir (Viracept) 
• Rifampin (Rifadin, in Rifamate, in Rifater, Rimactane) 
• Ritonavir (Norvir, in Kaletra) 

These drugs mentioned above may interact with clindamycin and require adjustment of dosages or closer monitoring for potential adverse effects. 

Disclose your medical history to your doctor or pharmacist, especially if you have a history of: 

• Liver or kidney disease 
• Any gastrointestinal conditions, such as colitis or C. difficile-associated diarrhea 
• Allergic conditions, such as asthma, hay fever, or eczema 

Prior to receiving any immunizations or vaccinations, inform your healthcare provider of the use of Cleocin, for it has been known to compromise the efficacy of live bacterial vaccines, including the typhoid vaccine. 

The safety of administering Cleocin to pregnant women and its potential effects on fetal development remains uncertain. Inform the physician of your pregnancy or intentions to conceive before initiating treatment with Cleocin. 

Clindamycin can enter the breast milk during lactation and potentially induce adverse effects in the nursing infant. Consult your doctor before breastfeeding. 

If the infant presents symptoms such as diaper rash, oral/throat redness or white patches, stomach discomfort, or watery/bloody diarrhea while the mother is taking this medication, it is essential to contact a medical professional.