Indications 

Cozaar is a prescription medication categorized as an angiotensin II receptor blocker (ARB) indicated for: 

• Treatment of high blood pressure in adults and children over six years old. By lowering blood pressure, Cozaar helps reduce the risk of serious heart and blood vessel problems, like strokes and heart attacks 
• Reduction of the risk of stroke in people with high blood pressure and a condition called left ventricular hypertrophy 
• Treatment of diabetic nephropathy, a kidney disease that can occur in people with type 2 diabetes and high blood pressure 

Losartan potassium, the active ingredient of Cozaar, works by inhibiting the action of angiotensin II, a substance that constricts blood vessels. This mechanism results in the dilation of blood vessels, facilitating a smoother blood flow and lowering blood pressure. 

Uses and Dosage 

Before starting treatment with Cozaar and with each refill, thoroughly review its patient information leaflet and medication guide. Seek guidance from a healthcare professional for any questions or concerns. 

The dosing and administration of Cozaar are individualized based on the medical condition and response to the treatment. Age and body weight are also considered for pediatric patients. 

Typically, Cozaar is initiated at the lowest effective dose once daily and titrated upwards gradually. It can be co-administered with other antihypertensive agents and can be taken with or without food. 

Follow the prescribed dosage regimen for Cozaar precisely, without taking more or less than the recommended dose or taking it more frequently than directed by the physician. 

For optimal results, take Cozaar regularly. A dosing schedule may help you remember intake and reduce the likelihood of unintentional medication omission. 

Side Effects 

Potential adverse reactions that may arise from Cozaar’s administration are listed below. If any of these symptoms persist or worsen, notify your physician or pharmacist. 

Common Side Effects 

• Dizziness 
• Back pain 
• Cold symptoms such as a stuffy nose, sneezing, and sore throat 

Serious Side Effects  

• Lightheadedness 
• Pain or burning sensation during urination 
• Nausea 
• Weakness 
• Tingling sensation 
• Chest pain 
• Irregular heartbeat 
• Loss of mobility 
• Decreased or no urine output 
• Rapid weight gain 
• Swelling in the hands, feet, or ankles.  

Get medical help right away if any of the above serious side effects are experienced. 

Allergic Reactions 

Severe allergic response to Cozaar is uncommon. However, seek immediate medical assistance if you observe any indications of an allergic reaction, such as: 

• Rash 
• Swelling or itching, particularly in the face, tongue, or throat 
• Difficulty breathing 
• Intense dizziness. 

The side effects of Cozaar listed here are incomplete. If you experience other bothersome side effects not listed above, consult with a healthcare professional. 

Cautions 

Prior to taking Cozaar, notify your doctor or pharmacist of any known allergies you may have. Inactive components present in this medication can cause allergic reactions or other unfavorable effects. Please seek further information from your pharmacist. 

Disclose your medical history to your doctor, particularly if you have had any of the following conditions: 

• Liver disease 
• Dehydration 
• High level of potassium in the blood 

Certain products may have interactions with Cozaar, including but not limited to: 

• Aliskiren 
• Lithium 
• Drugs that have the potential to raise potassium levels in the bloodstream (such as ACE inhibitors like benazepril/lisinopril and birth control pills with drospirenone) 

Certain products contain components that could potentially exacerbate heart failure or increase blood pressure, particularly: 

• Cough-and-cold products 
• Diet aids 
• NSAIDs like ibuprofen/naproxen 

To avoid potential drug interactions, tell your doctor or pharmacist about all medications you are currently taking, including prescription/non-prescription, supplements, and herbal products. 

Cozaar may potentially elevate the potassium levels in your body. Seek advice from your physician or pharmacist before taking potassium supplements or using salt substitutes that contain potassium. 

Black patients, such as African American with high blood pressure and left ventricular hypertrophy may not benefit from Cozaar. Consult your doctor for more suitable medication. 

Consumption of alcohol or marijuana (cannabis) may intensify Cozaar’s side effects, such as dizziness. Refrain from driving, operating machinery, or performing any activity that requires alertness until you can do so safely.  

Limit alcohol intake and talk with your doctor if using marijuana (cannabis).