Creon 10 (Pancreatic enzyme) Medication


Creon 10 (Pancreatic enzyme)

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Creon 10 is a prescribed medication indicated for individuals with exocrine pancreatic insufficiency (EPI), a condition characterized by insufficient enzyme production due to factors such as cystic fibrosis, chronic pancreatitis, pancreatectomy, or other related conditions, resulting in impaired food digestion. 

As a pancreatic enzyme replacement therapy (PERT), Creon 10 functions by replacing the three key pancreatic enzymes (lipase, protease, and amylase) typically produced by a healthy pancreas. This aids in reducing excessive fat in bowel movements and enhances nutritional absorption by breaking down fats, proteins, and starches from food into more readily absorbable components within the intestines. 

Uses and Dosage 

Before taking Creon 10 and with every prescription refill, carefully read the accompanying medication guide and patient information leaflet. If you have any inquiries or need further clarification, do not hesitate to seek guidance from your doctor or pharmacist. 

The dosage of this medication can differ among individuals depending on their medical conditions, diet, weight, and response to the treatment. 

Typically, Creon 10 is taken in accordance with the doctor’s instructions with each meal and snack.  

The capsules must be swallowed whole, without crushing or chewing, along with sufficient water to ensure proper ingestion. Do not suck or hold the capsule in your mouth, as it may irritate the inner lining of your mouth. 

If you have difficulty swallowing the capsule, you can open it and mix the contents with a small amount of liquid or soft food (such as room-temperature applesauce). Swallow the mixture without chewing and follow it with water or juice. Do not save the mixture for later use. 

Avoid mixing the capsule contents with alkaline foods or liquids. Consult your doctor or pharmacist for more information on which foods and liquids to avoid when mixing. 

Refrain from inhaling the powder from the capsule or allow direct skin contact, as it can potentially induce irritation, particularly in the nasal and respiratory areas. 

When consuming numerous meals or snacks daily, consult your doctor for guidance to avoid exceeding your daily prescribed dosage. Taking more of this medication than directed by your doctor will not expedite recovery and may heighten the likelihood of side effects. 

Keep taking Creon 10 even if you feel well, and refrain from discontinuing treatment without consulting your doctor. 

In case of a missed dose of Creon 10, contact your doctor or wait until your next meal to consume the regular number of capsules. Ensure that your next dose is taken at the regular scheduled time, and refrain from compensating for any missed doses. 

Side Effects 

The potential adverse effects of Creon 10 are outlined below. Tell your doctor promptly if any of these symptoms continue or deteriorate. 

Common Side Effects 

  • Stomach pain, gas, vomiting 
  • Diarrhea, frequent or irregular bowel movements 
  • Rectal itching 
  • Headache, dizziness 
  • Runny or stuffy nose, cough, sore throat 
  • Alterations in blood sugar levels 

Serious Side Effects 

  • Joint inflammation or pain 
  • Indications of an uncommon yet severe bowel disorder:  
    • Intense or unusual stomach discomfort 
    • Vomiting 
    • Bloating 
    • Diarrhea 
    • Constipation 

Inform your doctor without delay if you encounter any severe side effects. 

Allergic Reactions 

In rare cases, Creon 10 may trigger a severe allergic response. Prompt medical attention should be sought if any symptoms of an allergic reaction are noticed, including: 

  • Hives 
  • Difficulty breathing 
  • Face, tongue, or throat swelling 

This list does not cover all side effects of Creon 10. Should you experience any unlisted effects, consult your doctor or pharmacist. 


Before starting treatment with Creon 10, inform your doctor if you have any known allergies, particularly to pork protein or any ingredients found in Creon capsules. 

Disclose to your doctor your medical background before taking Creon 10 to ensure its appropriateness for your condition, especially if you have a history of: 

  • Acute pancreatitis (sudden and severe pancreatic inflammation) 
  • Rapid deterioration of chronic pancreatic disease 
  • Gout 
  • Kidney disease 
  • Hyperuricemia (elevated blood uric acid levels) 
  • Intestinal issues like blockage 

Acarbose and miglitol can interact with Creon 10. To reduce the risk of such interactions, inform your doctor about all your current or intended medications, including prescription and over-the-counter medicines, dietary supplements, and herbal products. 

Seek advice from your doctor regarding the appropriate use of Creon 10 during pregnancy, considering the potential risks and benefits involved. 

Before breastfeeding, seek guidance from your healthcare provider as this medication’s passage into breast milk remains unclear. 

Additional information

Generic name:

Pancreatic enzyme


DR Capsule, Delayed Release Capsule


150mg, 10000/11200/730 units

Quantities Available:


Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Creon 10 (Pancreatic enzyme). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Creon 10 (Pancreatic enzyme).