Delzicol (Mesalamine) Medication

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Delzicol (Mesalamine)

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Description

Table of contents:


Drug Description

Indications 

Delzicol (mesalamine) is a medication classified as an aminosalicylate, and primarily used for the treatment of gut inflammation. Specifically, it effectively manages and prevents flare-ups of ulcerative colitis, an inflammatory bowel disease (IBD). Ulcerative colitis is characterized by autoimmune dysfunction, wherein the body’s immune system mistakenly attacks the gastrointestinal tract, leading to inflammation, ulcers, and swelling in the colon and rectum. 

The primary function of Delzicol is to reduce the inflammation associated with ulcerative colitis. Its anti-inflammatory properties are believed to stem from its ability to block the enzyme cyclooxygenase (COX) and inhibit the production of prostaglandins in the colon. Both COX and prostaglandins play crucial roles in generating an inflammatory response. 

Delzicol is formulated as a delayed-release capsule designed to dissolve only at a pH of 7 or higher. This specific feature allows the drug to be released directly into the terminal ileum and colon, where its anti-inflammatory action is most needed to alleviate symptoms and promote healing. 

 Uses and Dosage 

To ensure the proper use of Delzicol delay-release capsules, follow your doctor’s instructions carefully. Here are some essential guidelines to keep in mind: 

  • Take Delzicol as your doctor directs, adhering to the prescribed dosage and schedule. 
  • Delzicol can be taken with or without food. 
  • Swallow the Delzicol capsules whole without cutting, breaking, crushing, or chewing them. 
  • If you have difficulty swallowing the Delzicol capsules, you may open them and eat the four inner tablets. Again, avoid cutting, breaking, crushing, or chewing the tablets. 
  • Drink an adequate amount of fluids while taking Delzicol. 
  • Delzicol is available as 400mg delayed-release capsules. Delzicol 400mg capsules are not interchangeable or substitutable with mesalamine delayed-release 800mg tablets. Do not substitute your Delzicol capsules with any other mesalamine-containing medication unless specifically instructed by your healthcare professional. 

Side Effects 

Common Side Effects 

  • Stomach upset 
  • Nausea/vomiting 
  • Constipation 
  • Headache 
  • Joint/muscle pain 

If side effects persist or worsen, inform your doctor or pharmacist promptly. 

Presence of whole or partial tablets/capsules in stool: Inform your doctor if this frequently occurs, as it may indicate inadequate medication absorption. 

Worsening of ulcerative colitis: Notify your doctor immediately if symptoms worsen after starting the medication, such as increased abdominal pain/cramping or bloody diarrhea. 

Serious Side Effects 

  • Persistent nausea/vomiting 
  • Signs of kidney problems (e.g., change in urine amount, blood in urine) 
  • Dark urine 
  • Severe stomach/abdominal pain 
  • Yellowing of eyes/skin 
  • Chest pain 
  • Shortness of breath 

Allergic Reaction 

Seek immediate medical assistance if you observe symptoms of a severe allergic reaction, including: 

  • Fever 
  • Swollen lymph nodes 
  • Rash 
  • Itching/swelling (especially of face/tongue/throat) 
  • Severe dizziness 
  • Trouble breathing 

Cautions 

Before starting mesalamine, inform your doctor or pharmacist about your allergies, including mesalamine, other aminosalicylates, salicylates, or sulfasalazine. Disclose any other allergies, as the medication may contain inactive ingredients that can cause allergic reactions. Consult your pharmacist for more details. 

Discuss your medical history with your doctor or pharmacist, especially if you have kidney disease, liver disease, or stomach blockage. 

Be cautious of increased sun sensitivity when using this medication, especially if you have skin conditions like atopic dermatitis or eczema. Minimize sun exposure, avoid tanning booths and sunlamps, and use sunscreen and protective clothing. Notify your doctor if you experience sunburn or skin issues. 

Inform your doctor or dentist about all the medications, including prescriptions, over-the-counter drugs, and herbal products you are using, before undergoing surgery. 

Children and teenagers under 18 should avoid aspirin or aspirin-related medications if they have chickenpox, flu, an undiagnosed illness, or have recently received a vaccine, as it increases the risk of Reye’s syndrome. 

Use this medication only if necessary during pregnancy, and discuss the risks and benefits with your doctor. 

Consult your doctor before breastfeeding, as this medication passes into breast milk and may have adverse effects on the nursing infant. 

For further information, seek advice from your pharmacist or physician. 

Additional information

Generic name:

Mesalamine

Formulation:

DR Capsule

Strength(s):

400mg

Quantities Available:

180

Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Delzicol (Mesalamine). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Delzicol (Mesalamine).