Dermasone Ointment (Clobetasol Propionate) Medication

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Drug Description


Dermasone Ointment is a prescribed medication indicated for the treatment of various skin conditions, including allergic reactions, eczema, and psoriasis. 

Classified as a highly potent corticosteroid, Dermasone Ointment works by stimulating the body’s natural compounds to alleviate skin inflammation, redness, and itching. 

Uses and Dosage 

Before using Dermasone Ointment and with each prescription refill, thoroughly review the product packaging and accompanying patient information leaflet. Consult your doctor or pharmacist for any inquiries or additional information. 

Dermasone Ointment is for topical skin use only and should not be used for ophthalmic, oral, or intravaginal purposes. 

Do not use this ointment on the face, groin, or underarms unless directed by your doctor. 

Typically, this ointment is applied twice daily to the affected skin area. 

To ensure proper ointment application: 

  1. Start by washing and drying your hands. 
  2. Thoroughly cleanse and dry the affected area. 
  3. Apply a thin coat of the ointment to the affected site and gently massage it according to your doctor’s guidelines. 
  4. Following application, wash your hands unless you are using the ointment to treat your hands. 

When using Dermasone Ointment near the eyes, exercise caution to prevent any contact with the eyes, which may worsen or trigger glaucoma. Moreover, avoid applying this ointment to the nose or mouth. If accidental application occurs in these regions, rinse thoroughly with plenty of water. 

Refrain from applying this ointment to large skin areas or covering the treated site with a bandage or any other covering unless directed by your doctor.  

Avoid wearing plastic pants or snug-fitting diapers when applying the ointment in the diaper area. 

For optimal results, adhere closely to the prescribed usage of Dermasone Ointment for the intended condition. Avoid extending continuous application beyond two weeks or exceeding a weekly usage of 50 grams unless directed otherwise by your doctor. 

Inform your doctor if your condition does not improve or deteriorates after two weeks. 

Side Effects 

The potential side effects of Dermasone Ointment are listed below. If any of these symptoms last or worsen, promptly notify your doctor. 

Common Side Effects 

  • Sensation of burning, itching, swelling, or irritation in the treated area 
  • Skin dryness or cracking 
  • Redness or crusting around hair follicles 
  • Spider veins 
  • Stretch marks or skin thinning 
  • Rash or hives 
  • Acne 
  • Temporary hair loss 

Serious Side Effects 

  • Worsening of skin condition 
  • Redness, heat, swelling, discharge, or severe discomfort in the treated skin area 
  • Blurred vision, tunnel vision, eye discomfort, or seeing halos around lights 
  • Signs of elevated blood sugar: 
    • Increased thirst or urination 
    • Dry mouth 
    • Fruity breath odor 
  • Potential indications of ointment absorption by the skin: 
    • Facial and shoulder weight gain 
    • Delayed wound healing 
    • Skin discoloration 
    • Skin thinning 
    • Increased body hair 
    • Fatigue 
    • Changes in mood 
    • Alterations in menstrual patterns 
    • Changes in sexual function 

Call your doctor immediately if you experience any of the serious side effects listed above. 

Allergic Reactions 

In rare cases, Dermasone Ointment may trigger a severe allergic reaction. Seek immediate medical help if you observe any signs of a severe allergic response, such as: 

  • Hives 
  • Trouble breathing 
  • Face, lips, tongue, or throat swelling 

This list does not cover all side effects of Dermasone Ointment. If unmentioned effects occur, inform your doctor. 


Before starting treatment with Dermasone Ointment, inform your doctor if you have any known allergies, particularly to clobetasol, other corticosteroids such as hydrocortisone and prednisone, or any of the non-active components contained within this ointment. 

Disclose your medical history with your doctor before using Dermasone Ointment to assess its appropriateness for your condition, particularly if you have a history of: 

  • Impaired blood circulation 
  • Weakened immune system 
  • Certain skin conditions (rosacea or perioral dermatitis) 

Dermasone Ointment typically does not exhibit interactions with other medications, but the possibility of drug interactions remains. Notify all healthcare professionals about your comprehensive medication regimen, encompassing prescribed drugs, over-the-counter remedies, vitamins, and herbal supplements. 

Refrain from applying Dermasone Ointment if the treatment area exhibits signs of infection or an open sore. 

Children using Dermasone Ointment may face a higher risk of side effects, such as reduced growth and delayed weight gain. Consult your child’s doctor regarding the potential risks associated with applying this medication to your child’s skin. 

Advise your doctor of your pregnancy status, as the impact of Dermasone Ointment on a developing fetus remains uncertain. 

The safety of breastfeeding while using Dermasone Ointment is uncertain. Consult your doctor for potential risks and avoid applying the ointment to areas that may contact the baby’s mouth. 

Additional information

Generic name:

Clobetasol Propionate





Quantities Available:

15g, 30g

Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Dermasone Ointment (Clobetasol Propionate). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Dermasone Ointment (Clobetasol Propionate).