Diane 35 (Cyproterone Acetate/Ethinyl Estradiol) Medication


Diane 35 (Cyproterone Acetate/Ethinyl Estradiol)

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Table of contents:

Drug Description


Diane-35 (Cyproterone acetate + Ethinylestradiol) is recommended for treating moderate to severe acne in women of reproductive age who have androgen sensitivity, with or without seborrhoea or hirsutism. It should be considered when topical treatments or systemic antibiotics have been ineffective in managing acne symptoms. Diane-35 is both a hormonal contraceptive and an acne treatment. Therefore it should not be used concurrently with other hormonal contraceptives as indicated in the contraindications. 

Uses and Dosage 

The recommended dosing regimen for this medication is a 28-day cycle, consisting of one tablet taken daily for 21 consecutive days, followed by a 7-day interval without prescription. Take the tablet at the same time each day. Treatment is typically initiated on the first day of menstrual bleeding. 

Common for several months of continuous treatment to be necessary before noticeable improvement in acne symptoms is observed. Once the acne has completely cleared, the medication is often continued for 3 or 4 cycles and then discontinued. However, if the acne returns, the medicine may be restarted. 

If you experience spotting or breakthrough bleeding during the three weeks of active medication intake, this drug is generally advised to continue taking the medication. This type of bleeding is usually temporary. However, if the bleeding persists or lasts extended, you must contact your doctor. 

If your menstrual period does not occur during the 7-day tablet-free interval, you should not start the next medication cycle and consult your doctor. 

Side Effects 

Medications can have various side effects, which are unwanted reactions to standard doses of the medicine. These side effects can range from mild to severe and may be temporary or long-lasting. 

Not everyone who takes this medication will experience the following side effects. If you have concerns about side effects, discussing the medicine’s risks and benefits with your doctor is essential. 

At least 1% of individuals taking this medication have reported the following side effects. Many of these side effects can be managed; some may resolve independently over time. 

Suppose you experience any of these side effects that are severe or bothersome, advisable to contact your doctor. Your pharmacist can guide managing these side effects. 

  • Abdominal cramps and bloating 
  • Changes in appetite 
  • Breast pain, tenderness, or swelling 
  • Development of brown, blotchy spots on exposed skin 
  • Discomfort when wearing contact lenses 
  • Dizziness 
  • Excessive hair growth on the face, chest, or legs 
  • Hair loss 
  • Headache 
  • Increased or decreased interest in sexual intercourse 
  • Irritability 
  • Menstrual pain 
  • Mood changes 
  • Nausea 
  • Nervousness 
  • Rash or reddish lumps under the skin 
  • Formation of red or purple spots or patches under the skin 
  • Runny or stuffy nose 
  • Swelling of the ankles and feet 
  • Unusual tiredness or weakness 
  • Vomiting 
  • Weight gain or loss 

If you experience any other unusual symptoms, consult your healthcare provider. 


Before initiating any medication, you must provide your doctor with comprehensive information regarding your medical history, existing allergies, current medication regimen, pregnancy or breastfeeding status, and any other pertinent details concerning your health. These factors can influence the appropriate way to take the medication and any necessary precautions to consider. Open communication with your healthcare provider ensures your treatment plan is tailored to your needs and circumstances. 

Additional information

Generic name:

Cyproterone Acetate/Ethinyl Estradiol, Cyproterone Acetate/ethinyl estradiol





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Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Diane 35 (Cyproterone Acetate/Ethinyl Estradiol). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Diane 35 (Cyproterone Acetate/Ethinyl Estradiol).