Epiduo Gel (Adapalene Benzoyl Peroxide) Medication


Epiduo Gel (Adapalene Benzoyl Peroxide)

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Drug Description


Epiduo gel is intended for the dermatological management of acne vulgaris in patients aged nine years and above, administered through topical application. 

Epiduo Gel, comprising adapalene and benzoyl peroxide, is a synergistic combination of a vitamin A-like medication and an antibacterial agent with mild drying properties. Epiduo Gel is prescribed for treating acne in individuals aged 12 years and above. 

Uses and Dosage 

EPIDUO gel is indicated for topical application exclusively and should not be used orally, ophthalmically, or intravaginally. Following a thorough cleansing routine, a thin film of EPIDUO gel should be applied to the affected areas of the face and trunk once daily. To ensure proper dosage, a quantity equivalent to the size of a pea should be used for each area of the face, such as the forehead, chin, and each cheek. Exercise caution and prevent contact with the eyes, lips, and mucous membranes during application. 

Side Effects 

The use of Epiduo Gel may result in common side effects, such as:  

  • Skin redness 
  • Dryness 
  • Peeling 
  • Mild burning 
  • Stinging 
  • Scaling 
  • Swelling 
  • Itching 
  • Temporary worsening of acne during the initial four weeks of treatment 

Typically, these side effects diminish with regular usage of Epiduo Gel. Note that a severe allergic reaction to Epiduo is rare; however, immediate medical attention should be sought if severe symptoms occur. These symptoms may include:  

  • Rash 
  • Itching 
  • Swelling (especially of the face, tongue, or throat) 
  • Severe dizziness 
  • Difficulty breathing 


Prior to using this product, inform your doctor or pharmacist about any known allergies to:  

  • Adapalene 
  • Benzoyl peroxide 
  • Vitamin A-related drugs (including other retinoids like isotretinoin) 
  • Any other substances 

This product may contain inactive ingredients that could potentially trigger allergic reactions or other complications. Therefore, consult your pharmacist for further information. 

Furthermore, before using this medication, disclose your medical history to your doctor or pharmacist, particularly if you have any pre-existing skin conditions, such as eczema. 

Due to the potential risk of harm to an unborn baby, women who are pregnant or may become pregnant should avoid handling this medication, as Epiduo Gel is absorbed through the skin. 

Additional information

Generic name:

Adapalene Benzoyl Peroxide





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Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Epiduo Gel (Adapalene Benzoyl Peroxide). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Epiduo Gel (Adapalene Benzoyl Peroxide).