Dyazide (Triamterene/ Hctz) Medication

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Drug Description


Dyazide is indicated for the treatment of hypertension, as it effectively mitigates high blood pressure, consequently reducing the incidence of strokes, heart attacks, and kidney complications. This pharmaceutical formulation comprises a combination of two diuretics, triamterene, and hydrochlorothiazide, commonly referred to as “water pills.”  

The utilization of this combination therapy is particularly beneficial for individuals who have either developed or are at risk of experiencing low potassium levels while taking hydrochlorothiazide. By augmenting urine production, Dyazide facilitates the elimination of excessive salt and water from the body. 

This medication exerts a diuretic effect that effectively reduces fluid retention (edema) associated with conditions such as heart failure, liver disease, or kidney disease. Consequently, it alleviates symptoms such as dyspnea and edema in the ankles or feet, improving patient comfort and well-being. 

Uses and Dosage 

Dyazide is a pharmaceutical product that requires a prescription, primarily prescribed to address conditions characterized by fluid retention (edema) and high blood pressure (hypertension). 

Patients who have previously experienced hypokalemia (low potassium levels in the blood) due to the use of other diuretics often benefit from the administration of Dyazide. 

The medication should be taken orally as instructed by the healthcare professional, typically once daily in the morning, with or without food. To avoid nocturnal disruptions due to increased urination, refrain from taking Dyazide within four hours of bedtime. 

In cases where the patient takes specific cholesterol-lowering medications such as bile acid-binding resins (e.g., cholestyramine or colestipol), observe a minimum time interval of four hours before or four to six hours after the intake of Dyazide. 

The appropriate dosage of Dyazide is determined based on the individual’s medical condition and response to treatment, with careful consideration given to optimizing therapeutic outcomes. 

Side Effects 

During the initial period of treatment, as their body adapts to the medication, it’s uncommon for patients to experience:  

  • Dizziness 
  • Lightheadedness 
  • Headache 
  • Upset stomach  

If any of these effects persist or worsen, inform your doctor or pharmacist. 

To minimize the risk of dizziness and lightheadedness, rise slowly from a seated or lying position. 

In the event that any of the following uncommon but serious side effects manifest, notify your doctor:  

  • Fainting 
  • Muscle cramps or weakness 
  • Abnormal heart rhythm (slow, fast, or irregular) 
  • Changes in vision 
  • Eye pain 
  • Signs indicative of kidney problems (e.g., alterations in urine output) 


Prior to initiating the use of this medication, disclose your medical history to your doctor or pharmacist, particularly if you have a history of diabetes, gout, high potassium levels in the blood, kidney disease (including kidney stones), liver disease, lupus, or skin cancer. 

This drug has the potential to cause dizziness. Consumption of alcohol or marijuana (cannabis) can exacerbate this dizziness. Therefore, refrain from activities requiring alertness, such as driving or operating machinery, until you can safely perform them. limit alcohol intake. If you are using marijuana (cannabis), Discuss this with your doctor for appropriate guidance and advice. 

Additional information

Generic name:

Triamterene/ Hctz, Triamterene/Hctz




37.5/25mg, 50/25mg

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Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Dyazide (Triamterene/ Hctz). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Dyazide (Triamterene/ Hctz).