Emsam Patch (Selegiline) Medication


Emsam Patch (Selegiline)

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Drug Description


Emsam (selegiline) patch is a once-daily application on the skin and is prescribed for the treatment of depression in adults. It offers a viable alternative for individuals who are unable or prefer not to take oral medications. However, inform your healthcare provider about all the medications you are currently using, including prescriptions, over-the-counter drugs, and herbal supplements, as Emsam (selegiline) patch may interact with them. 

Uses and Dosage 

To ensure proper application of the Emsam (selegiline) patch, follow these guidelines: 

Prior to applying the patch, cleanse the skin gently using soap and warm water. Afterward, dry the area with a clean towel. 

The Emsam (selegiline) patch can be placed on the torso (below the neck and above the waist), upper thigh, or the outer part of the upper arm. Ensure that the chosen area of skin is dry, undamaged, and free of hair. 

Apply a fresh patch every day, removing the old one beforehand since only one patch should be worn at a time. Each time you change the patch, select a different area of skin to prevent skin irritation. Apply the patch around the same time daily. 

When removing the Emsam (selegiline) patch from its pouch, avoid cutting the pouch to prevent accidentally cutting the patch itself. Instead, tear the pouch open at the notches. Refrain from touching the sticky side of the patch. After applying the patch, wash your hands with soap and water to remove any medication residue before touching your eyes. 

If the patch falls off, press it firmly back onto the skin. If it continues to fall off, switch to a new patch while maintaining your regular schedule for changing patches. 

When removing the Emsam (selegiline) patch, do so slowly to avoid damaging the skin. If the patch proves difficult to remove, wash it with soap and water, then apply a thin layer of petroleum jelly or olive oil. This will help loosen the edges of the patch. 

Side Effects 

Common Side Effects

Common side effects may include: 

  • Dizziness 
  • Drowsiness 
  • Redness/irritation at the application site 
  • Tiredness 
  • Weakness 
  • Problems sleeping 
  • Constipation 
  • Dry mouth 

If these effects persist or worsen, notify your doctor or pharmacist. 

To minimize the risk of dizziness and lightheadedness, rise slowly from a seated or lying position. 

Severe Side Effects

This medication has been prescribed because its benefits outweigh the potential side effects. Serious side effects are rare in most individuals. 

Seek immediate medical attention if you experience any of the following serious side effects: 

  • Persistent nausea/vomiting 
  • Fainting 
  • Mental/mood changes (e.g., agitation, confusion) 
  • Muscle stiffness/twitching 
  • Changes in sexual ability/interest 
  • Tremors or shivering 
  • Swollen ankles/legs 
  • Unexplained weight gain/loss 
  • Eye pain/swelling/redness 
  • Changes in vision (e.g., double/blurred vision) 
  • Severe stomach/abdominal pain 
  • Seizures 
  • Dark urine 
  • Yellowing of the eyes/skin 


Due to uncertainty regarding the transfer of medication into breast milk, this drug is not advisable to breastfeed while using the Emsam (selegiline) patch. To ensure the safety of your baby, please abstain from breastfeeding throughout the duration of treatment and for an additional 5 days after discontinuing the medication. If you have concerns or inquiries regarding the management of your depression while breastfeeding, consult your healthcare provider for guidance. 

Inform your healthcare provider if you are pregnant or intending to conceive. Although limited data is available on the use of the Emsam (selegiline) patch in pregnant individuals, studies on animals have demonstrated potential risks to developing fetuses. If you have concerns or inquiries regarding the management of your depression during pregnancy, discuss them with your healthcare provider for personalized advice and guidance. 

Additional information

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6mg, 12mg

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Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Emsam Patch (Selegiline). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Emsam Patch (Selegiline).