ErybiD (Erythromycin Base) Medication

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Drug Description


Erybid is a prescribed medication used to treat a range of bacterial infections, including respiratory tract infections (e.g., bronchitis, pneumonia, Legionnaires’ disease, and pertussis), diphtheria, sexually transmitted diseases (STDs), and infections of the ear, intestine, gynecological system, urinary tract, and skin.  

Moreover, Erybid may serve as a preventive measure for recurrent rheumatic fever. 

Classified as a macrolide antibiotic, Erybid functions by inhibiting bacterial growth.  

Uses and Dosage 

Before taking Erybid and with each prescription refill, carefully review the accompanying medication guide and patient information leaflet. For questions or additional information, consult your doctor or pharmacist. 

The dosage and duration of Erybid treatment are determined by the patient’s medical condition and response to therapy. For children, dosage is additionally influenced by age and weight. 

Typically, this antibiotic is administered on an empty stomach (at least 1/2 hour and preferably 2 hours before meals). 

It may be prescribed to be taken at intervals of every 6 hours (four times daily), every 8 hours (three times daily), or every 12 hours (twice daily). 

Erybid tablets should be ingested whole with a full glass of water. Avoid chewing or crushing the tablet, as it tastes bitter when crushed. 

For optimal results, take Erybid at evenly spaced intervals. To enhance adherence, take it at around the same time each day. 

Adhere strictly to your doctor’s instructions on how to take this antibiotic and refrain from altering the prescribed dosage, frequency, and duration of intake. 

Complete the full prescribed course of Erybid, even if symptoms resolve within days. Premature discontinuation may lead to a recurrence of the infection.  

Inform your doctor if your condition persists or deteriorates. 

Side Effects 

Listed below are the potential side effects of Erybid. Inform your doctor should any of these effects persist or worsen. 

Common Side Effects 

  • Nausea 
  • Vomiting 
  • Diarrhea 
  • Stomach pain or cramping 
  • Loss of appetite 

Serious Side Effects 

  • Signs of liver disease: 
    • Persistent nausea/vomiting 
    • Yellowing of eyes or skin 
    • Dark urine 
    • Severe stomach/abdominal pain 
  • Unusual tiredness and muscle weakness 
  • Difficulty speaking, blurred vision, drooping eyelids, and hearing loss 

Tell your doctor right away if any of the serious side effects above are experienced. 

Severe Side Effects: 

  • Severe dizziness 
  • Fainting 
  • Fast/irregular heartbeat 

Get immediate medical help if any of the severe side effects occur. 

The use of Erybid may lead to the development of a severe intestinal condition caused by C. difficile bacteria. This condition can manifest during treatment or several weeks to months after its completion. Promptly notify your healthcare provider if you experience: 

  • Unrelenting diarrhea 
  • Abdominal pain 
  • Cramping 
  • Presence of blood or mucus in stool 

Avoid using anti-diarrhea or opioid products if you experience the symptoms above, as they may exacerbate the condition. 

Prolonged or repeated usage of Erybid can cause oral thrush or a new yeast infection. If you notice white patches in your mouth, experience changes in vaginal discharge, or encounter any other novel symptoms, contact your doctor. 

Allergic Reactions 

In rare instances, Erybid may provoke a critical allergic response. Promptly seek medical aid should any symptoms of an allergic reaction manifest, such as: 

  • Rash 
  • Itching or swelling (particularly of the face, tongue, or throat) 
  • Severe dizziness 
  • Breathing difficulties 

This list does not cover all side effects of Erybid. Should you exhibit any other effects, inform your doctor. 


Before starting treatment with Erybid, inform your doctor if you have any known allergies, particularly to erythromycin, macrolide antibiotics such as azithromycin and clarithromycin, or any other ingredient in this enteric coated tablet. 

Disclose your medical history with your doctor before taking Erybid to assess its appropriateness for your condition, particularly if you have a history of: 

  • Kidney disease 
  • Liver disease 
  • Myasthenia gravis (muscle disease) 

Erybid may interact with other medications, including Digoxin. To minimize the risk of such drug interaction, inform all your healthcare providers of your complete medication regimen, including prescription and nonprescription medicines, vitamins, and herbal supplements. 

The efficacy of Erybid may be altered by other drugs that impact its elimination from the body. This includes: 

  • Azole antifungals (e.g., itraconazole, ketoconazole) 
  • Specific calcium channel blockers (diltiazem, verapamil)  
  • Certain anti-seizure medications (carbamazepine, phenytoin) 
  • Quinupristin-dalfopristin 
  • Saquinavir 

On the other hand, Erybid can inhibit the metabolism of various medications, potentially altering their effectiveness. This includes drugs like: 

  • Bromocriptine 
  • Colchicine 
  • Benzodiazepines (e.g., midazolam, triazolam) 
  • Eletriptan 
  • Ergot alkaloids (e.g., ergotamine, dihydroergotamine) 
  • Medicines for erectile dysfunction or pulmonary hypertension (e.g., sildenafil, tadalafil) 
  • Statin drugs (e.g., lovastatin, simvastatin) 
  • Vinblastine 

Before undergoing any vaccinations, disclose your Erybid usage to your healthcare professional, as it can potentially impair the efficacy of live bacterial vaccines like the typhoid vaccine. 

Erybid has the potential to lead to a heart rhythm disturbance known as QT prolongation. In rare instances, this can result in a serious, and occasionally fatal, rapid, or irregular heartbeat and other symptoms like severe dizziness and fainting, necessitating immediate medical attention. 

Inadequate blood potassium or magnesium levels may enhance the potential for QT prolongation. This risk is further exacerbated when using certain drugs (such as diuretics) or experiencing conditions like excessive perspiration, diarrhea, or vomiting. Discuss the safe administration of Erybid with your healthcare provider. 

Erybid can potentially disrupt specific lab tests (urine tests), leading to inaccurate results. Inform laboratory staff and your healthcare providers about your use of this antibiotic. 

Inform your doctor of your pregnancy status and intentions prior to commencing Erybid treatment. 

Erythromycin can be transmitted into breast milk. Consult your doctor before breastfeeding to assess the safety of your nursing child. 

Additional information

Generic name:

Erythromycin Base


Enteric coated Tablets



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Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about ErybiD (Erythromycin Base). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about ErybiD (Erythromycin Base).