Indications 

Loxapac is prescribed for managing symptoms associated with schizophrenia, a mental disorder characterized by disrupted or atypical thinking, diminished life engagement, and intense or unsuitable emotions. 

Loxapac belongs to the class of drugs called antipsychotics. The exact way this medication works is not fully understood, but it appears to recalibrate the balance of natural brain chemicals (dopamine and serotonin) that facilitate nerve cell communication. 

Uses and Dosage 

Before the initial use and with each prescription refill of Loxapac, carefully read the medication guide and patient information leaflet provided by your pharmacist. Should you have any questions or need further information, consult your doctor or pharmacist. 

Loxapac dosage is determined based on individual medical conditions and response to the treatment. Your doctor may direct you to start this medication at a low dose and gradually adjust it. 

Typically, this medication is taken 2 to 4 times daily as directed by your doctor. Ensure to take the tablets with a full glass of water. 

Take Loxapac regularly, exactly as prescribed, to maximize its benefits. To aid in adherence, take it at the same time(s) daily. 

In case of a missed dose, take it promptly once remembered. But if your next dose is approaching, omit the missed one and resume the regular schedule. Avoid taking a double dose. 

Do not increase the dosage or take this medication more frequently without consulting your doctor. Doing so will not expedite improvement in your condition but may heighten the risk of serious side effects. 

Furthermore, refrain from discontinuing Loxapac without consulting your doctor, as certain conditions may deteriorate if this medication is abruptly ceased. 

Side Effects 

Common Side Effects 

• Dizziness, balance, or walking issues 
• Facial swelling 
• Itching or rash 
• Tremors, muscle twitching, or stiffness 
• Numbness, weakness 
• Blurred vision 
• Restlessness or agitation 
• Nausea, vomiting, constipation 
• Dry mouth, stuffy nose 
• Insomnia 

Inform your doctor if any of these common side effects last or worsen. 

Serious Side Effects 

• Involuntary muscle movements in limbs or face (chewing, lip smacking, frowning, or tongue or eye movement) 
• Rapid heartbeat 
• Feeling light-headed or faint 
• Confusion, slurred speech 
• Agitation, sleep difficulties 
• Seizures  
• Reduced or absent urination 
• Severe constipation 
• Indication of low white blood cell counts: 
  • Fever 
  • Chills 
  • Mouth or skin sores 
  • Sore throat 
  • Cough 
  • Breathing difficulties 
  • Lightheadedness 
• Severe nervous system reaction: 
  • Rigid muscles 
  • High fever 
  • Sweating 
  • Confusion 
  • Fast heartbeat 
  • Tremors 
  • Feeling faint 

Call your doctor right away if you have any of these serious side effects. 

Allergic Reactions 

Although rare, a severe allergic reaction to Loxapac can occur. Seek immediate medical aid if any of the following symptoms manifest: 

• Hives 
• Trouble breathing 
• Face, lips, tongue, or throat swelling 

This list does not include all potential side effects of Loxapac. Inform your doctor if you exhibit any effects not mentioned here. 

Cautions 

Before starting treatment with Loxapac, inform your doctor if you have any known allergies, particularly to loxapine or any inactive components in the tablet. 

To ensure Loxapac is safe for you, disclose to your doctor your medical background, especially if you have a history of: 

• Blood issues (low red/white/platelet cell counts) 
• Glaucoma 
• Heart problems (fast/irregular heartbeat, low blood pressure) 
• Liver disease 
• Brain disorder/tumor/injury 
• Drug/alcohol/substance abuse 
• Breast cancer 
• Parkinson’s disease 
• Seizures 
• Severe reaction to other antipsychotic medications (neuroleptic malignant syndrome – NMS) 
• Difficulty urinating (e.g., due to prostate problems) 

Loxapac might interact with other medications like metoclopramide and certain Parkinson’s disease medications (bromocriptine, levodopa, pergolide). To mitigate these interactions, inform your doctor about all your current and recent medication use, including prescriptions, over-the-counter drugs, vitamins, and herbal supplements. 

Review medication labels (e.g., allergy or cold products) for potential drowsiness-inducing ingredients and ask your doctor or pharmacist for their safe usage. Moreover, inform them about any other drowsiness-causing products you are taking, including: 

• Opioid pain relievers 
• Alcohol 
• Marijuana 
• Sleep or anxiety medications 
• Muscle relaxants 
• Antihistamines 

Prolonged or high-dose usage of Loxapac can lead to an irreversible movement disorder. Extended use, particularly for women or older adults, increases the risk of developing this condition. 

Loxapac takes time to take effect, and initial treatment might increase the occurrence of thoughts about self-harm or suicide. If these thoughts arise, contact your healthcare provider immediately or seek urgent care at a hospital. 

Refrain from driving or operating machinery until you understand your response to Loxapac, as it may cause drowsiness or blurred vision in some individuals. 

The use of Loxapac can induce dizziness, fainting, or lightheadedness, particularly when rising from a lying position. To prevent this, rise gradually from bed by resting your feet on the floor for a few minutes before standing up. 

Take precautions to prevent overheating and dehydration when exercising or in hot conditions. Loxapac can reduce sweating, increasing the risk of heat stroke. 

Loxapac use can increase sun sensitivity. Limit sun exposure, avoid tanning booths and sunlamps, use sunscreen, and wear protective clothing outdoors. Notify your doctor immediately if you experience sunburn or skin redness/blistering. 

Loxapac is not intended for use in elderly patients with dementia due to a higher risk of mortality associated with similar medications in this demographic. 

Loxapac should only be used during pregnancy if your doctor determines that the benefits to you significantly outweigh the potential risks to the fetus. 

Infants born to mothers taking Loxapac during pregnancy may face significant health issues. These problems might improve spontaneously, but immediate medical assistance is crucial if your baby experiences: 

• Breathing difficulties 
• Excessive drowsiness 
• Muscle stiffness or limpness (like a rag doll) 
• Tremors or shaking 
• Feeding difficulties 

Breastfeeding is not recommended during treatment with Loxapac.