Indications 

Memantine is prescribed for managing cognitive impairment of moderate to severe intensity associated with Alzheimer’s disease. While it does not constitute a curative intervention for Alzheimer’s disease, it has demonstrated the potential to enhance cognitive faculties, augment awareness, and facilitate the execution of daily activities. 

The mechanism of action of this medication involves the inhibition of a specific endogenous neurotransmitter in the brain, glutamate, which is hypothesized to be intricately involved in the manifestation of Alzheimer’s disease symptoms. 

Uses and Dosage 

Take this medication orally once daily as directed by your physician. Swallow the capsules whole; do not crush or chew them to prevent potential adverse reactions. If swallowing whole is difficult, you can open the capsule and sprinkle the contents on applesauce but consume it immediately. Do not prepare this mixture in advance. 

The dosage depends on your condition and response; your doctor may start with a low dose and adjust it as needed. Follow your doctor’s instructions closely. 

If transitioning from another form of memantine to the extended-release version, consult your healthcare provider before switching. 

For optimal effectiveness, take the medication at the same time every day. 

Side Effects 

Common Side Effects

Possible adverse effects of this medication include: 

• Back pain 
• Dizziness 
• Drowsiness 
• Constipation 
• Weight gain 
• Abdominal discomfort 
• Vomiting 
• Urinary incontinence 

If these manifestations endure or exacerbate, promptly apprise your healthcare provider or pharmacist. 

Severe Side Effects

Keep in mind that your healthcare professional has prescribed this medication based on their assessment that the potential benefits outweigh the risk of side effects. Most individuals using this medication do not experience severe adverse reactions. 

Promptly inform your physician if you eperience severe side effects, such as:  

• Alterations in mental state or mood  
• Depression 
• Aggression  

While exceedingly rare, a severe allergic reaction to this medication is possible. Seek immediate medical attention should you observe any indications of an extreme allergic response, including skin rash, itching, swelling (particularly of the face, tongue, or throat), profound dizziness, or breathing difficulties. 

Cautions 

Before initiating memantine therapy, inform your healthcare provider or pharmacist of any known allergies, including allergies to memantine itself or any other substances. This medication may incorporate inert components that elicit allergic reactions or other complications. For additional information, consult your pharmacist. 

Before commencing treatment with this medication, disclose your medical history to your healthcare provider or pharmacist, particularly if you have an account of kidney ailments, severe urinary tract infections, or recent dietary alterations (such as transitioning from a high-protein diet to a vegetarian one).