Indications 

Nix Dermal Cream is a topical medication used to treat scabies, a skin condition caused by mite Sarcoptes scabiei that burrows into the skin and causes intense itching. 

The cream contains (5% Permethrin) which is a synthetic pyrethroid insecticide that works by targeting the nervous system of the mites and lice, causing paralysis and death. It works by paralyzing and killing the mites and their eggs that cause scabies infections. 

Use and Dosage 

Nix Dermal Cream is applied a thin layer of cream all over your skin from your neck down to your toes (including the soles of your feet). Be careful to apply cream in all skin folds, such as between your toes and fingers or around your waist or buttocks. 

To use Nix Dermal Cream, follow these steps: 

1. Make sure your skin is clean and dry before applying the cream. 
2. Apply a thin layer of cream all over your skin from your neck down to your toes, including the soles of your feet. 
3. Massage the cream into your skin until it is fully absorbed. 
4. Leave the cream on your skin for 8 to 14 hours. 
5. After 8 to 14 hours, wash off the cream by showering or taking a bath. 
6. Put on clean clothes and bedding. 
7. Repeat the application in 7 days if necessary. 

To prevent re-infection, all clothing, bedding, and towels used by an infected person 2 days before treatment should be machine-washed with hot water and dried in the dryer on the hot cycle for at least 20 minutes or dry-cleaned. Mattresses used by an infected person should not be used for 48 hours, and toilet seats and combs should be disinfected.  

Side Effects 

Common Side Effects 

• Itching 
• Mild burning or stinging 
• Numbness or tingling of the skin 
• Redness, numbness, tingling, or rash 

Serious Side Effects 

• Continued irritation of the skin or scalp area 
• Infected or pus-filled areas of the skin or scalp area 
• Skin pain 
• Skin puffiness 
• Trouble breathing 

Cautions 

• Allergic reaction: If you are allergic to Permethrin or any other ingredients in Permethrin, do not use it. Signs of an allergic reaction may include rash, hives, itching, swelling, dizziness, or difficulty breathing. Seek medical attention immediately if you experience any of these symptoms. 
• Use during pregnancy and breastfeeding: Although Nix Dermal Cream is considered safe to use during pregnancy and breastfeeding, consult with a healthcare professional before using it. 
• Use in children: Nix Dermal Cream is generally safe to use in children older than 2 months of age. However, follow the recommended dosage and application instructions for children, as they may be more sensitive to the medication. 
• Avoid contact with eyes and mouth: Do not apply Permethrin to your eyes, mouth, or inside your nose. If the medication comes into contact with these areas, rinse thoroughly with water. 
• Avoid contact with open wounds: Do not apply it to open wounds or broken skin. 
• Use as directed: Follow the recommended dosage and application instructions carefully. Do not use more than directed or for longer than recommended. 
• Skin irritation: Some people may experience skin irritation, such as itching, redness, or swelling, after using Permethrin. If you experience any of these symptoms, contact your healthcare professional. 
• Drug interactions: Permethrin may interact with other medications you are taking. Inform your healthcare professional of all medications you are taking, including over-the-counter medications, supplements, and herbal remedies. 
• Avoid re-infestation: To avoid re-infestation, wash all clothes, bedding, and towels in hot water and dry them on high heat. Items that cannot be washed should be placed in a sealed plastic bag for at least 72 hours. 
• Avoid close contact: To prevent the spread of scabies, avoid close contact with others until the infection has cleared up. 
• Follow up: Follow up with your healthcare professional after using Nix Dermal Cream to ensure that the infection has been fully treated.