Tarka (Trandolapril/Verapamil) Medication


Tarka (Trandolapril/Verapamil)

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This medicinal product is indicated for the management of hypertension. By reducing elevated blood pressure levels, it can effectively mitigate the risk of serious conditions such as stroke, heart attack, and renal disorders.  

This therapeutic formulation consists of two active ingredients, namely trandolapril and verapamil. Trandolapril belongs to the angiotensin-converting enzyme (ACE) inhibitor class, while verapamil belongs to the calcium channel blocker class.  

These pharmacological agents exert their therapeutic effects by inducing vasodilation, resulting in enhanced blood flow. Verapamil has the potential to decrease heart rate. 

Uses and Dosage 

Prior to commencing treatment with trandolapril/verapamil, kindly refer to the Patient Information Leaflet, provided by your pharmacist. Should you have any queries, do not hesitate to consult your healthcare provider. 

This medication should be administered orally with food, once or twice daily, in accordance with your physician’s instructions. The tablets should be swallowed whole, and not crushed or chewed, as doing so may lead to rapid drug release and subsequent side effects. 

The recommended dosage is determined based on your medical condition and response to therapy. 

In order to maximize the therapeutic benefits of this medication, take it regularly at the same time(s) each day. Continue taking this medication even if you are feeling well, as hypertension is usually asymptomatic. 

Abrupt cessation of this medication may exacerbate certain conditions. Thus, please consult with your healthcare provider prior to discontinuing use. Dosage reductions may be necessary to facilitate gradual discontinuation. 

It may take a few weeks for the full therapeutic effect of this medication to manifest. 

Please notify your physician if your condition fails to improve or worsens, as indicated by persistent or increasing hypertension readings. 

Side Effects 

Allergic Reaction

Please seek immediate medical attention if you experience any signs of an allergic reaction, including hives, severe abdominal pain, breathing difficulties, or swelling of the face, tongue, throat, or lips. 

Severe Side Effects

Serious side effects associated with Tarka necessitate prompt medical consultation. Kindly contact your healthcare provider immediately if you experience any of the following symptoms: 

  • Light-headedness or a sensation of fainting 
  • Jaundice (yellowing of the skin or eyes) and upper abdominal pain 
  • Chest pain, a rapid, or slow or irregular heart rate 
  • High levels of potassium in the blood, indicated by nausea, chest pain, weakness, loss of movement, irregular heartbeats, or a tingling sensation 
  • Kidney dysfunction, characterized by swelling in the feet or ankles, decreased urination, fatigue, or shortness of breath 
  • Low white blood cell counts manifesting as mouth sores, skin sores, sore throat, cough, fever, chills, lightheadedness, or breathing difficulties 
  • Accumulation of fluid in or around the lungs, leading to wheezing, pain upon breathing, anxiety, rapid heartbeat, coughing up frothy sputum, cold, or clammy skin 

Common Side Effects  

  • Cough 
  • Cold-like symptoms, including a runny or blocked nose, sore throat, or sneezing 
  • Headache and dizziness 
  • Back or chest pain 
  • Constipation 
  • Fatigue 
  • Abnormal liver function tests 


Before taking this medication, inform your doctor or pharmacist of any allergies you have, including allergies to trandolapril or verapamil, other ACE inhibitors such as benazepril or lisinopril, or any other allergies you may have. This medication may contain inactive ingredients that can cause allergic reactions or other complications. Speak to your pharmacist to obtain more information about this. 

This medication can cause dizziness, and using alcohol or marijuana (cannabis) may exacerbate this effect. Avoid driving, operating machinery, or performing any activity that requires alertness until you can do so safely. Limit alcoholic beverages and speak with your doctor if you are using marijuana (cannabis). 

Excessive sweating, diarrhea, or vomiting can cause dehydration and increase the risk of lightheadedness. If you experience prolonged diarrhea or vomiting, inform your doctor. Be sure to drink enough fluids to avoid dehydration, unless your doctor directs you otherwise. 

This medication may increase your potassium levels. Speak with your doctor or pharmacist before using potassium supplements or salt substitutes that contain potassium. 

Before undergoing surgery, inform your doctor or dentist of all the products you are using, including prescription drugs, nonprescription drugs, and herbal products. 

Older adults may be more sensitive to the side effects of this medication, especially dizziness, increases in potassium levels, constipation, swelling ankles/feet, and changes in the amount of urine (kidney problems). 

Inform your doctor if you are pregnant or planning to become pregnant. You should not become pregnant while using trandolapril/verapamil. This medication can harm an unborn baby. If you become pregnant, speak with your doctor right away about the risks and benefits of using this medication. Consult your doctor for more details. 

Additional information

Generic name:





2/180mg, 2/240mg, 4/240mg

Quantities Available:

84, 100

Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Tarka (Trandolapril/Verapamil). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Tarka (Trandolapril/Verapamil).