Indications 

Vibra-Tab is a prescribed medication used to address diverse bacterial infections, including acne-inducing ones. 

Vibra-Tab is also indicated for malaria prevention, post-exposure anthrax treatment, and other conditions determined by a healthcare professional. 

As a tetracycline antibiotic, Vibra-Tab functions by eradicating or inhibiting bacterial growth. Nevertheless, it does not exhibit efficacy against colds, flu, or any viral infections. 

Uses and Dosage 

Before taking Vibra-Tab and every time you get a prescription refill, carefully review the medication guide and patient information leaflet provided by your pharmacist. If you have any concerns or inquiries, do not hesitate to consult with your healthcare provider or pharmacist. 

Vibra-Tab dosage is determined based on the patient’s medical condition and treatment response, considering weight in pediatric cases. 

Typically, Vibra-Tab is taken once or twice daily on an empty stomach as directed by the doctor (at least 1 hour before or 2 hours after eating). Take the tablets with a full glass of water unless otherwise instructed. 

If stomach upset occurs, this medication may be taken with food or milk, though its effectiveness might be reduced in such cases. Consulting your doctor or pharmacist for guidance is recommended. 

For malaria prevention, follow your doctor’s instructions, typically taking this medication once daily, starting 1 to 2 days before traveling to a malarious area. Maintain daily use throughout your stay in the region. After returning home, continue for an additional 4 weeks. If unable to complete the prescribed course, consult your doctor. 

To maximize efficacy, adhere to a regular schedule when taking this medication. To aid in remembering, ensure to take it at the same designated time(s) daily. 

Complete the entire prescribed course of Vibra-Tab, even if your symptoms improve within a few days. Ceasing the medication prematurely could permit bacterial growth, potentially leading to a recurrence of the infection. 

Side Effects 

Listed below are the potential adverse effects of Vibra-Tab. Inform your doctor promptly if any of these symptoms persist or worsen. 

Common Side Effects 

• Stomach upset 
• Diarrhea 
• Nausea 
• Vomiting  

Serious Side Effects 

• Painful/difficult swallowing 
• Signs of kidney problems (e.g., change in the amount of urine) 

Tell your doctor right away if you encounter any of the serious side effects above. 

Tetracycline drugs, like Vibra-Tab, can rarely lead to increased pressure in the brain (intracranial hypertension-IH). This risk is higher for overweight women of childbearing age or those with a history of IH. If IH occurs, it typically resolves after discontinuing this medication; however, permanent vision loss is possible. Seek immediate medical assistance if experiencing severe or persistent headaches, unrelenting nausea and vomiting, or vision changes. 

Vibra-Tab can rarely lead to a severe intestinal condition caused by the bacterium C. difficile. This condition may arise during treatment or weeks to months after treatment cessation. If you experience persistent diarrhea, abdominal pain/cramps or notice blood/mucus in your stool, promptly inform your doctor. Avoid using anti-diarrhea or opioid products if you have these symptoms, as they may exacerbate the condition. 

Long-term or frequent use of Vibra-Tab can lead to oral thrush or a fresh vaginal yeast infection. Consult your physician if you observe white patches in your mouth, alterations in vaginal discharge, or any other unfamiliar symptoms. 

Allergic Reactions 

Although rare, a severe allergic reaction to Vibra-Tab may occur. Prompt medical attention must be sought upon noticing any signs of an allergic reaction, such as: 

• Persistent fever 
• Enlargement of lymph nodes, new or worsening 
• Skin rash 
• Itching or swelling, particularly in the face, tongue, or throat 
• Severe dizziness 
• Difficulty breathing 

Not all side effects of Vibra-Tab are included in this list. Inform your doctor of any unlisted effects that may arise. 

Cautions 

Before starting treatment with Vibra-Tab, inform your doctor if you have any known allergies, particularly to doxycycline hyclate or to other tetracyclines (e.g., minocycline). 

This antibiotic may contain inactive ingredients that may trigger allergic reactions or other complications. For more information, seek guidance from your pharmacist. 

To ensure Vibra-Tab is safe for you, disclose to your physician your medical background, especially if you have a history of difficulty with swallowing or 

esophageal issues, such as hiatal hernia or reflux/heartburn 

Inform all your healthcare providers about your complete medication regimen, including prescriptions, over-the-counter medicines, vitamins, and herbal products, to reduce the risk of drug interaction with Vibra-Tab. 

Some of the products that may interact with Vibra-Tab include: 

• Oral retinoid medications (e.g., acitretin, isotretinoin) 
• Barbiturates (e.g., phenobarbital) 
• Blood thinners (e.g., warfarin) 
• Digoxin 
• Anti-seizure medications (e.g., phenytoin) 
• Strontium 

Vibra-Tab should be administered at least 2 to 3 hours apart from substances containing aluminum, calcium, iron, magnesium, zinc, or bismuth subsalicylate, as they can interfere with the absorption of doxycycline. Examples of such substances include: 

• Antacids 
• Didanosine solution  
• Quinapril 
• Vitamins/minerals  
• Dairy products like milk and yogurt 
• Calcium-enriched juice 

Vibra-Tab can potentially affect specific laboratory tests, like urine catecholamine levels, leading to inaccurate results. Ensure that laboratory staff and your healthcare providers are aware of your use of this antibiotic. 

Inform your healthcare provider of your use of Vibra-Tab before receiving any immunizations, as it may hinder the effectiveness of live bacterial vaccines, including the typhoid vaccine. 

Plan to minimize unnecessary or extended sun exposure and use protective measures like clothing, sunglasses, and sunscreen while using Vibra-Tab, as it can increase skin sensitivity to sunlight. Notify your doctor immediately if you experience sunburn. 

Vibra-Tab alone does not provide complete protection against malaria. Complement its use with additional protective measures, including effective insect repellent, mosquito nets, full-body clothing coverage, and staying in well-screened areas, particularly during the early nighttime until dawn. 

Children under the age of 8 may exhibit increased sensitivity to Vibra-Tabs side effects, particularly tooth discoloration. This adverse effect has also been observed in older children and young adults. Consult with a doctor to thoroughly evaluate the risks and benefits associated with this medication. 

Inform your doctor of your pregnancy status or intentions. Pregnancy while taking Vibra-Tab should be avoided as it may harm the developing fetus. If you become pregnant, promptly consult your doctor to assess the medication’s risks and benefits. 

Discuss with your healthcare provider the use of alternative birth control methods as Vibra-Tab may reduce the efficacy of hormonal contraceptives such as pills, patches, rings, or injections. 

Doxycycline can be transferred to breast milk. Prior to breastfeeding, consult with your healthcare provider.