Indications 

Vibramycin is a tetracycline antibiotic that exhibits bacteriostatic properties by inhibiting protein synthesis in susceptible bacteria. 

Indicated for the treatment of a wide range of bacterial infections, Vibramycin is particularly effective against acne, urinary tract infections, intestinal infections, eye infections, gonorrhea, chlamydia, periodontitis (gum disease), and other infections. 

Vibramycin has been found effective in treating blemishes, bumps, and acne-like lesions associated with rosacea, but it does not alleviate the facial redness caused by the disease. 

In addition to these indications, certain formulations of doxycycline (the active ingredient in Vibramycin) may be used to prevent malaria, treat anthrax, or manage infections caused by mites, ticks, or lice. 

Uses and Dosage 

Before taking doxycycline, read the Patient Information Leaflet provided by their pharmacist. Any questions should be directed to the patient’s doctor or pharmacist.  

This medication is taken orally on an empty stomach, at least one hour before or two hours after a meal, as directed by the doctor. A full glass of water (8 ounces/240 milliliters) should be taken with the medication, unless advised otherwise.  

If stomach upset occurs, taking the medication with food or milk may be helpful, although it may reduce the effectiveness of the medication. Patients are advised not to lie down for at least 10 minutes after taking the medication.  

Do not to take this medication within two to three hours of products containing aluminum, calcium, iron, magnesium, zinc, or bismuth subsalicylate, such as antacids, didanosine solution, quinapril, vitamins/minerals, dairy products (such as milk, yogurt), and calcium-enriched juice, as they can interfere with the absorption of doxycycline. 

The dosage of doxycycline is determined based on the patient’s medical condition and response to treatment, with dosing for children taking weight into account. To achieve the best effect, patients should take this antibiotic at evenly spaced times and at the same time(s) every day to help with adherence.  

Take the full prescribed amount of the medication until finished, even if symptoms disappear after a few days. Discontinuing the medication prematurely may allow bacteria to grow and result in the return of the infection. 

Side Effects 

Allergic Reaction

Signs of an allergic reaction or severe skin reaction: 

• Hives 
• Difficulty breathing 
• Swelling in your face or throat 
• Fever 
• Sore throat 
• Burning in your eyes 
• Skin pain 
• Red or purple skin rash that spreads and causes blistering and peeling 

Severe Side Effects

Symptoms of a serious drug reaction: 

• Skin rash 
• Fever 
• Swollen glands 
• Flu-like symptoms 
• Muscle aches 
• Severe weakness 
• Unusual bruising 
• Yellowing of your skin or eyes 

Call your doctor at once if you experience: 

• Severe stomach pain 
• Watery or bloody diarrhea 
• Throat irritation 
• Trouble swallowing 
• Chest pain 
• Irregular heart rhythm 
• Shortness of breath 
• Little or no urination 
• Low white blood cell counts 
• Increased pressure inside the skull 
• Signs of liver or pancreas problems 

Common Side Effects 

• Nausea, vomiting, upset stomach, loss of appetite 
• Mild diarrhea 
• Skin rash or itching 
• Darkened skin color 
• Vaginal itching or discharge 

Cautions 

Before taking doxycycline, inform your doctor or pharmacist if you have any allergies to doxycycline, other tetracyclines (such as minocycline), or any other substance contained in the medication, as it may contain inactive ingredients, like sulfites or soy, that can cause allergic reactions or other complications. Consult your pharmacist for more information. 

You should nform your doctor or pharmacist about your medical history, particularly if you have difficulty swallowing, esophagus problems (such as hiatal hernia or reflux/heartburn) or if you are taking any live bacterial vaccines (such as typhoid vaccine), as doxycycline may interfere with their efficacy. 

If you plan to have surgery, let your doctor or dentist know that you are taking this medication. 

Doxycycline can increase sensitivity to sunlight, limit sun exposure, avoid tanning booths and sunlamps, and use sunscreen and protective clothing when outdoors. If you experience sunburn or skin blisters or redness, contact your doctor immediately. 

Discuss the risks and benefits of using doxycycline with your doctor, particularly if you are a child younger than 8 years of age, as this medication may cause tooth discoloration in children of this age group. Tooth discoloration may occur in older children and young adults.