Indications 

Zoladex LA is a medication indicated for the treatment of various conditions, including prostate cancer in men and certain types of breast cancer in pre- and peri-menopausal women.  

Zoladex is a long-acting form of goserelin, a luteinizing hormone-releasing hormone (LHRH) analog. works by suppressing the production of certain hormones, such as testosterone in men and estrogen in women. By reducing the levels of these hormones, it helps to slow down or inhibit the growth of cancer cells in the body. 

Use and Dosage 

Zoladex LA is typically administered as a subcutaneous injection every 4 weeks or every 12 weeks, depending on the specific condition being treated. The injection should be performed by a healthcare professional in a clinical setting to ensure proper administration and minimize any potential risks or complications. Take these injections performed by a qualified healthcare professional within a clinical setting. 

To ensure optimal results, follow your doctor’s instructions regarding the administration of Zoladex LA. If you miss an appointment for your medication, promptly contact your doctor to make arrangements for a rescheduled appointment. 

Dosage adjustments may be necessary based on your medical background, current condition, and how you respond to the treatment. Strictly follow the prescribed dosing schedule and avoid missing any doses.  

Side Effects 

Common Side Effects 

• Acne  
• Bone pain 
• Breast swelling or tenderness 
• Change in breast size 
• Constipation 
• Diarrhea 
• Dizziness 
• Fewer erections than usual 
• Hair loss mental/mood changes (such as depression mood swings hallucinations) 
• Headache 
• Hot flashes (flushing) 
• Impotence 
• Increased or decreased sexual interest 
• Increased sweating 
• Injection site reactions (pain bruising bleeding redness or swelling) 
• Nausea 
• Skin rash or itching 
• Sleep problems (insomnia) 
• Trouble sleeping 
• Vaginal dryness/itching/discharge 

Serious Side Effects 

• Back pain 
• Blurred vision 
• Bone pain 
• Chest pain or pressure 
• Confusion 
• Constipation 
• Difficulty breathing 
• Drowsiness 
• Dry mouth 
• Dry skin 
• Fruity breath odor 
• Hives 
• Hunger 
• Increased thirst 
• Increased thirst or urination 
• Increased urination 
• Loss of bladder or bowel control 
• Muscle pain 
• Muscle weakness 
• Nausea 
• Pain bruising swelling redness oozing or bleeding where the implant was injected 
• Pain spreading to your jaw or shoulder 
• Painful or difficult urination 
• Problems with balance or coordination 
• Problems with vision or balance 
• Restlessness 
• Severe numbness or tingling in your legs or feet 
• Slurred speech and 
• Sudden numbness or weakness (especially on one side of the body) 
• Sudden severe headache 
• Sweating 
• Swelling of your face lips tongue or throat 
• Tiredness 
• Vomiting 
• Weakness 
• Weight loss 

Cautions 

• Drug Interactions: Zoladex LA may interact with other medications, including prescription drugs, nonprescription drugs, and herbal supplements.  
• Prostate Cancer: Zoladex LA is primarily used for the treatment of prostate cancer. Zoladex LA is not a cure for prostate cancer but can help manage the condition. Regular monitoring and follow-up with a healthcare provider are necessary to assess the effectiveness and monitor for any potential complications. 
• Breast Cancer: Goserelin may also be used in the treatment of certain types of breast cancer. It is typically used in combination with other medications or therapies.  
• Long-term Effects: Goserelin may have long-term effects on the body, including potential cardiovascular problems. Discuss the potential risks and benefits of Zoladex LA treatment with your healthcare provider. 
• Pregnancy and Breastfeeding: do not use goserelin during pregnancy or breastfeeding. It may harm the fetus or pass into breast milk. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and alternatives with your healthcare provider. 
• Allergic Reactions: Some individuals may experience allergic reactions to Zoladex LA. Signs of an allergic reaction may include rash, itching, swelling, severe dizziness, or difficulty breathing. If you experience any of these symptoms, seek immediate medical attention. 
• Liver or Kidney Problems: Zoladex LA is primarily eliminated from the body through the liver and kidneys. If you have pre-existing liver or kidney problems, your healthcare provider may need to adjust the dosage or closely monitor your condition while you are on Zoladex LA. 
• Osteoporosis and Bone Density Loss: Zoladex LA may contribute to bone density loss and increase the risk of osteoporosis. Discuss this potential risk with your healthcare provider, especially if you have a history of osteoporosis or are at an increased risk for developing it. 
• Cardiovascular Health: Goserelin may have an impact on cardiovascular health. Inform your healthcare provider if you have a history of cardiovascular disease, such as heart attacks, strokes, or blood clots, as Zoladex LA may increase the risk of these conditions. 
• Diabetes: Zoladex LA may affect blood sugar levels and can potentially interfere with diabetes management. Individuals with diabetes should closely monitor their blood sugar levels and work closely with their healthcare provider to adjust their diabetes medications if necessary. 
• Fertility: Goserelin may cause temporary or permanent infertility in both men and women. If maintaining fertility is a concern, discuss this with your healthcare provider before starting treatment.