Indications 

Mexitil is a prescribed medication used to treat life-threatening documented ventricular arrhythmias (abnormal heart rhythms), including sustained ventricular tachycardia, as determined by the physician. 

As an anti-arrhythmic drug, Mexitil works by inhibiting specific cardiac electrical signals to establish and maintain a stable heart rhythm. 

Uses and Dosage 

Before starting treatment with Mexitil and with each prescription refill, carefully review its medication guide and patient information leaflet. In case of any inquiries or uncertainties, consult your physician or pharmacist for guidance. 

The dosage of Mexitil is individualized based on age, liver function, medical condition, and response to the treatment. 

Typically, this medication is taken thrice a day, every 8 hours. However, a twice-daily regimen at 12-hour intervals may be recommended for individuals whose arrhythmias are effectively managed with Mexitil. 

To avoid stomach upset, take Mexitil with food or an antacid. Take it consistently at the same times daily to achieve optimal results. 

Keep taking Mexitil exactly as prescribed, even if you feel fine. Ceasing the use of this medication abruptly without consulting your doctor can potentially exacerbate your condition. 

Side Effects 

Listed below are the potential adverse effects of Mexitil. Inform your doctor if any of them last or worsen. 

Common Side Effects 

• Heartburn, upset stomach, nausea, or vomiting 
• Dizziness or lightheadedness 
• Tremors or nervousness 
• Coordination difficulties 
• Blurred vision 

Serious Side Effects 

• Chest pain 
• New or worsening irregular heartbeat pattern 
• Liver problems: 
  • Nausea 
  • Upper stomach pain 
  • Itching 
  • Fatigue 
  • Loss of appetite 
  • Dark urine 
  • Clay-colored stools 
  • Jaundice (yellowing of the skin or eyes) 

Call your doctor promptly if you experience any of the severe side effects mentioned above. 

Allergic Reactions 

Although rare, a severe allergic reaction to Mexitil may occur. Get prompt medical assistance if you observe any of the following symptoms: 

• Fever 
• Swollen lymph nodes 
• Rash 
• Itching or swelling, particularly of the face, tongue, or throat 
• Severe dizziness 
• Difficulty breathing 

This list does not contain all the potential side effects of Mexitil. If you experience any unlisted effects, tell your doctor right away.  

Cautions 

Before starting treatment with Mexitil, inform your doctor and pharmacist if you have any known hypersensitivities, especially to mexiletine, other medications, or any ingredients present in Mexitil capsules. 

To ensure Mexitil is safe for you, disclose to your physician your medical background, especially if you have a history of: 

• Other heart problems (e.g., heart failure, bradycardia, previous heart attack) 
• Liver problems 
• Seizure disorder 

Mexitil can potentially interact with certain products, including: 

• Caffeine 
• Theophylline 
• Medications that impact urine acidity (e.g., sodium bicarbonate, high-dose vitamin C) 

To mitigate the risk of such drug interactions, tell your doctor and pharmacist about all prescription, nonprescription medications, vitamins, nutritional supplements, and herbal products you currently use or intend to use. 

The efficacy of Mexitil may be influenced by the presence of other medications that affect its elimination from the body. Such medications include: 

• Cimetidine 
• Fluvoxamine 
• Propafenone 
• Anti-seizure drugs (e.g., phenytoin, phenobarbital) 

Mexitil is contraindicated for individuals with significant heart conditions, such as “AV block,” unless they have a pacemaker. 

The use of Mexitil may lead to abnormal liver function test results, particularly if you have congestive heart failure or blood circulation issues. 

Exercise caution when taking Mexitil, as it may cause dizziness or lightheadedness. Refrain from driving or operating machinery until you know the medication’s impact on your body. 

The potential risks of Mexitil to an unborn baby are uncertain. Inform your doctor if you are pregnant or intend to become pregnant while taking this medication. 

Mexiletine can be transmitted through breast milk and poses a risk to a nursing infant. If Mexitil usage is necessary, an alternative approach to infant feeding must be evaluated.