Indications 

Nitrostat Sublingual is a prescribed medication used to alleviate angina (chest pain) caused by coronary artery disease, either during an attack or as a preventive measure. 

As a vasodilator, Nitrostat Sublingual works by widening blood vessels to facilitate smoother blood flow, making it easier for the heart to pump. 

Uses and Dosage 

Before taking Nitrostat Sublingual for the first time and with every prescription refill, carefully review the provided medication guide and patient information leaflet. Speak to your doctor or pharmacist if you have any questions. 

Nitrostat Sublingual is intended to be placed under the tongue for dissolution and should not be chewed or swallowed. 

The dosage of this medication may vary per individual based on medical conditions and response to the treatment. 

Typically, Nitrostat Sublingual is taken as needed, 5 to 10 minutes before activities that may trigger angina attacks or at the onset of an attack. 

During an attack, up to three tablets may be taken at an interval of five minutes. If no relief is experienced after three tablets in 15 minutes or if the pain differs from the usual, seek immediate medical assistance. Do not exceed three doses during an attack unless directed by your doctor. 

For optimal results, take Nitrostat Sublingual exactly as prescribed by your doctor. Use the minimum number of tablets necessary to alleviate pain during attacks, as the effectiveness of this medication may diminish with prolonged use or frequent doses. 

Should you experience an increase in frequency, duration, or severity of angina attacks while undergoing treatment, promptly contact your doctor. 

Side Effects 

Common Side Effects 

• Headache 
• Dizziness 
• Lightheadedness 
• Nausea 
• Flushing 
• Burning or tingling sensation under the tongue 

Promptly notify your doctor if any of the common side effects listed persist or intensify. 

Serious Side Effects 

• Fainting 
• Rapid, irregular, or pounding heartbeat 

Tell your doctor right away if any of these serious side effects occur. 

Allergic Reactions 

Rarely, Nitrostat Sublingual may trigger severe allergic responses. Seek immediate medical attention if you experience any indications of a serious allergic response, including: 

• Rash 
• Swelling or itching, particularly of the face, tongue, or throat 
• Severe dizziness 
• Difficulty breathing 

This list does not include all potential side effects of Nitrostat Sublingual. Inform your doctor if you exhibit other side effects not listed here. 

Cautions 

Before starting treatment with Nitrostat Sublingual, inform your doctor if you have any hypersensitivities, particularly to nitroglycerin, nitrates, similar medications such as isosorbide mononitrate, or any inactive ingredients in this sublingual tablet. 

Disclose your medical history to your doctor before taking Nitrostat Sublingual, particularly if you have experienced: 

• Recent head injury 
• Anemia 
• Low blood pressure 
• Dehydration 
• Other heart problems like a recent heart attack 

Ensure that your doctor is aware of all your medications, including prescription and nonprescription medicines, vitamins, and herbal supplements, to reduce the potential for drug interactions with Nitrostat Sublingual. 

Some of the medications that can interact with Nitrostat Sublingual are: 

• Medicine for erectile dysfunction or pulmonary hypertension (such as sildenafil and tadalafil) 
• Specific drugs for migraine headaches (like ergotamine) 
• Riociguat 
• Vericiguat 

If you are taking medications causing dry mouth, Nitrostat Sublingual tablets may not dissolve easily. In such cases, utilize an artificial saliva product or chew gum to enhance saliva production for tablet dissolution. 

Be sure to inform lab personnel and all your doctors that you are taking Nitrostat Sublingual, as it could potentially alter certain lab test results (e.g., blood cholesterol levels) and cause them to be inaccurate. 

Nitrostat Sublingual may cause dizziness, lightheadedness, and fainting. To avoid this, get up slowly and rest your feet on the floor before standing. Be extra cautious to avoid falling during treatment. 

Headache during treatment with Nitrostat Sublingual can indicate the medication’s effectiveness. Your doctor may suggest using an over-the-counter pain reliever (e.g., acetaminophen, aspirin) for headaches. If headaches persist or intensify, promptly inform your doctor. 

Elderly individuals may experience heightened sensitivity to the potential side effects of Nitrostat Sublingual, particularly dizziness and lightheadedness, which may elevate the risk of falling. 

During pregnancy, Nitrostat Sublingual should be used only when essential, and its use should be discussed with your doctor, weighing the associated risks and benefits. 

Before taking Nitrostat Sublingual while breastfeeding, consult with your doctor, as it is uncertain whether nitroglycerin passes into breast milk or poses a risk to a nursing infant.