Indications 

Cerenia is a medication subject to federal regulation and can only be administered under the guidance of a licensed veterinarian. It is indicated to prevent acute vomiting and motion sickness in dogs. 

Cerenia belongs to the class of drugs called antiemetics. It works directly in the central nervous system blocking the pharmacological action of substance P (a neurotransmitter involved in vomiting), treating, and preventing vomiting from various causes. 

Uses and Dosage 

Prior to administering Cerenia and with each subsequent refill, thoroughly review the accompanying medication guide and informational leaflet. If any questions or concerns arise, consult your dog’s veterinarian to comprehensively understand the medication, including its potential risks and benefits. 

The dosage and length of intake of Cerenia may vary on the dog’s age, weight, condition, and response to the treatment. The usual dosing information for Cerenia is provided here. If you receive a different prescription, strictly follow the instructions provided by the veterinarian. 

To prevent vomiting due to motion sickness, the tablets should be administered in conjunction with a small amount of food two hours prior to travel. This is recommended for dogs 4 months of age and older, at a minimum dosage of 8 mg/kg (3.6 mg/lb) of body weight, administered once daily for a maximum of two consecutive days. 

For prevention of acute vomiting: 

• Dogs within the age range of 2 to 7 months are usually given a minimum dosage of 2 mg/kg (0.9 mg/lb.) of body weight, administered once daily for a maximum of five consecutive days. 
• Dogs 7 months of age and older are usually given a minimum dosage of 2 mg/kg (0.9 mg/lb.) of body weight, administered once daily until the resolution of the acute vomiting symptoms. 

Side Effects 

Adverse reactions associated with Cerenia treatment are listed below. If persistent or worsening symptoms occur, inform your dog’s veterinarian for re-evaluation. 

Common Side Effects 

• Diarrhea 
• Anorexia 
• Pain/vocalization upon injection 
• Lethargy 

Caution 

Cautions for humans: 

• Cerenia is intended for veterinary use only and should not be consumed by humans. Store this medication in a secure location, out of reach of children. If accidentally ingested, seek medical advice immediately. 
• Localized allergic skin reactions may occur in some individuals upon topical exposure. Prolonged or repeated exposure may result in skin sensitization. To prevent potential exposure, thoroughly wash hands with soap and water after administering the drug. 
• Cerenia has the potential to cause ocular irritation. In the event of accidental eye exposure, immediately flush the affected eye with water for at least 15 minutes and seek medical attention promptly. 

Cautions for Dogs: 

• The safety of Cerenia has not been established for certain groups of dogs, including those used for breeding, pregnant or lactating females, dogs with gastrointestinal obstruction, or dogs that have ingested toxins. Discuss the risks and benefits of this medication with a veterinarian before administering it. 
• Caution should also be exercised when administering Cerenia to dogs with hepatic dysfunction. 
• Inform your dog’s veterinarian about any other medications being administered to avoid potential drug interactions, particularly with NSAIDs, cardiac medications, anticonvulsants, and behavioral medications.