Effient (Prasugrel) Medication


Effient (Prasugrel)

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Table of contents:

Drug Description


Effient is a prescription medicine administered in conjunction with aspirin to patients with heart disease, such as those who have recently suffered a heart attack or have unstable angina, and who undergo a specific heart procedure known as angioplasty.  

Belonging to the anti-platelet medication class, it reduces the risk of additional severe heart and blood vessel issues, including heart attacks, strokes, and the formation of blood clots in stents. 

Effient mechanism of action involves inhibiting platelet aggregation and preventing the formation of dangerous blood clots. By exerting an “anti-platelet” effect, Effient helps to maintain smooth blood flow throughout the body. 

Uses and Dosage 

Before taking Effient and with each subsequent refill, thoroughly review its patient information leaflet and medication guide. For any questions or clarifications, consult your doctor or pharmacist. 

Effient dosage may vary based on the individual’s medical condition, weight, and response to the treatment. Usually, it is taken once a day with or without food and should be swallowed whole not divided, chewed, or crushed.  

For optimal results, take Effient regularly at the same time of the day daily. Follow how it is prescribed and refrain from altering the dosage, frequency, or duration of use unless directed to do so by a physician. 

Effient can prevent severe heart and blood vessel complications, but only when taken as directed. Do not stop intake without consulting a doctor as abrupt cessation may increase the risk of heart attack, blood clot formation, or mortality. 

Side Effects 

Potential adverse reactions associated with the use of Effient are listed below. If any of them persists or worsens, apprise your doctor promptly. 

Common Side Effects 

  • Nose bleeding 
  • Easy bruising or bleeding tendency (higher tendency in older adults) 

Serious Side Effects 

  • Sensation of fainting or dizziness 
  • Uncontrolled bleeding 
  • Presence of pink or brown urine 
  • Indicators of severe blood-clotting issues, such as: 
    • Rapid heart rate 
    • Weakness 
    • Pale skin 
    • Purple spots on the skin 
    • Fever 
    • Jaundice 
    • Stomach pain 
    • Breathing difficulties 
  • Manifestations of stomach bleeding, including: 
    • Bloody or tarry stools 
    • Vomiting of coffee ground-like substance 
    • Coughing up blood 
  • Symptoms of a stroke, like: 
    • Sudden weakness or numbness (usually on one side of the body) 
    • Severe headache 
    • Balance or vision problems 
    • Slurred speech 

Call your doctor at once if you experience any of the severe symptoms listed above. 

Allergic Reactions 

Serious allergic reactions may occur with Effient use, particularly if the patient has experienced a severe allergic response to clopidogrel (Plavix) or ticlopidine (Ticlid). 

 Seek medical assistance immediately if any of these symptoms occur: 

  • Facial swelling or hives around the lips, mouth, or throat 
  • Breathing or swallowing difficulties 
  • Chest pain or tightness 
  • Dizziness or fainting 

The enlisted adverse effects here are not an exhaustive compilation of the potential side effects linked to Effient. Should you encounter any bothersome effects not specified above, promptly seek medical advice from your doctor. 


Before starting treatment with Effient, inform your healthcare provider or pharmacist if you have any known allergies, especially to prasugrel, clopidogrel (Plavix), ticlopidine (Ticlid), any other medications, or any of the ingredients of this medication. Ask your pharmacist for a list of the ingredients. 

To ensure Effient is safe for you, disclose to your doctor your medical background, particularly if you have a history of: 

  • Blood conditions (e.g. hemophilia) 
  • Bleeding complications (e.g. gastrointestinal or cerebral bleeding) 
  • Brain blood clots (e.g. stroke or TIA) 
  • Recent significant trauma or surgery 
  • Liver impairment 
  • Stomach or intestinal ulcers 

Inform your doctor and pharmacist of all prescription and non-prescription drugs, supplements, vitamins, and herbal products that you are currently taking or intend to use.  

Be mindful to tell if you are taking any products listed below, for your doctor may need to modify the dosages of your medications or conduct close monitoring to detect potential side effects. 

  • Opioids like codeine 
  • Fentanyl (Duragesic, Subsys) 
  • Hydrocodone (Hysingla, Zohydro ER, in Vicodin) 
  • Morphine (Astramorph, Kadian) 
  • Oxycodone (in Percocet, in Roxicet, and others) 

Concurrent use of an NSAID and Effient may increase the risk of easy bruising or bleeding. Consult your doctor before taking any nonsteroidal anti-inflammatory drug (NSAID) including: 

  • Aspirin 
  • Ibuprofen 
  • Naproxen 
  • Advil 
  • Aleve 
  • Motrin 

Exercise caution when engaging in activities that may increase the risk of bleeding or injury while taking Effient. To reduce the likelihood of cuts, bruises, or injuries, take extra care while shaving and brushing your teeth. Be mindful when handling sharp objects like razors and nail cutters and avoid participating in contact sports. 

Pregnant women should consult a healthcare provider and weigh the potential benefits and risks of Effient considering its mechanism of action and the identified risk of bleeding. Potential risks to the fetus should also be carefully considered. 

The transfer of prasugrel into breast milk remains uncertain. Before breastfeeding, seek the guidance of a medical professional. 

Additional information

Generic name:





5mg, 10mg

Quantities Available:

28, 84, 90, 100

Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Effient (Prasugrel). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Effient (Prasugrel).