Indications 

Lovaza is a prescription medication comprising eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are omega-3 fatty acids. It is used along with a healthy diet to lower the levels of a type of fat called triglycerides in adults who have very high levels of this fat in their blood (hypertriglyceridemia). 

Lovaza belongs to the class of drugs called lipid-regulating agents and is believed to function by reducing the synthesis of triglycerides and other lipids in the liver. 

Uses and Dosage 

Before taking Lovaza and every time you get a refill, thoroughly review its medication guide and patient information leaflet. Do not hesitate to seek advice from your doctor or pharmacist for any questions or concerns. 

Lovaza’s dosage may vary per individual based on their medical condition and response to the treatment.  

Typically, Lovaza is administered at a daily dosage of 4 grams, which can be taken either as a single 4-gram dose (4 capsules) or as two 2-gram doses (2 capsules twice daily). Swallow the capsules whole and refrain from breaking, crushing, dissolving, or chewing them. 

Take Lovaza regularly around the same time daily, exactly as directed. Do not modify the dosage or frequency of administration without your doctor’s consent. 

Continue taking Lovaza even if you feel well, as most people with high triglycerides do not experience symptoms. It may take up to 2 months to notice Lovaza’s full therapeutic effects. 

Side Effects 

Listed below are potential adverse reactions associated with the use of Lovaza. Notify your physician or pharmacist promptly if any of these symptoms last or worsen. 

Common Side Effects 

• Decreased appetite 
• Gastrointestinal discomfort: 
  • Diarrhea 
  • Constipation 
  • Upset stomach 
  • Belching 
• Back pain 
• Dry mouth 
• Changes in taste perception 

Serious Side Effects 

• Chest pain 
• Uneven heartbeats 

Seek immediate medical attention if you experience any of the serious side effects listed above. 

Allergic Reactions 

Seek emergency medical attention if you experience symptoms of an allergic reaction, such as: 

• Rash 
• Severe dizziness 
• Trouble breathing 
• Facial, tongue, or throat itching/swelling 

The side effects of Lovaza listed here are not exhaustive. Contact your doctor promptly if you experience any unlisted side effects that are bothersome. 

Cautions 

Before starting treatment with Lovaza, inform your healthcare provider or pharmacist about any allergic reactions you may have had, especially to: 

• Omega-3 fatty acids like omega-3-acid ethyl esters, icosapent ethyl esters, and Omega-3-carboxylic acids 
• Fish  
• Shellfish such as clams, scallops, shrimp, lobster, crayfish, crab, oyster, mussels, and others 
• Other medications 
• Any of the ingredients in Lovaza capsules (you may ask your pharmacist for a list of ingredients) 

To ensure that Lovaza is safe for you, disclose to your doctor your medical history, particularly of:  

• Alcohol use 
• Diabetes 
• Liver disease 
• Underactive thyroid (hypothyroidism) 

Certain products may interact with Lovaza, including: 

• Drugs that can increase triglycerides 
  • Beta-blockers 
  • Estrogens 
  • Certain diuretics like thiazides 
• Other vitamins or supplements (e.g., fish, flaxseed, cod liver oils) 

To prevent such drug interactions, inform your healthcare provider and pharmacist of all current and planned medications, including prescriptions, over-the-counter medicines, supplements, and herbal products, before using Lovaza. 

The potential harm Lovaza can pose to an unborn baby is uncertain. Therefore, inform your doctor if you are pregnant or planning to conceive. If you conceive while using this medication, contact your doctor immediately. 

Studies have indicated that omega-3-acid ethyl esters are excreted in human milk. However, the impact on nursing infants is unclear. Therefore, it is advisable to consult a doctor before nursing an infant while taking Lovaza.