Indications 

Nolvadex D is a prescription medicine used to treat cancer. It can also be used to reduce the chances of breast cancer in high-risk patients, such as those with a family history of the disease or those with ductal carcinoma in situ (DCIS). 

Nolvadex D contains the active ingredient tamoxifen citrate. It belongs to a group of medications known as antineoplastics. It works by blocking the effects of the hormone estrogen in the body. Estrogen can promote the growth of certain types of breast cancers that are estrogen receptor-positive. By blocking estrogen’s effects, it can help prevent the growth and spread of these cancers. 

Use and Dosage 

Nolvadex D comes in the form of Tablet to take by mouth with or without food as directed by your doctor, usually once or twice daily for 5 years. Take Nolvadex D by mouth with or without food, as directed by your doctor. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet. 

The recommended dose of tamoxifen is usually 20 mg to 40 mg daily. It may be taken as a single dose or divided into two doses. Your doctor will determine the appropriate dosage for your specific condition. 

Take the medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice. 

Side Effects 

Common Side Effects 

• Bone pain 
• Changes in menstrual period 
• Constipation 
• Diarrhea 
• Genital itching 
• Hair loss (partial) or hair thinning 
• Headache 
• Hot flashes 
• Leg cramps 
• Lightheadedness 
• Mild nausea and vomiting 
• Muscle pain 
• Skin rash 
• Swelling of the feet, ankles, or lower leg 
• Taste alterations 
• Tiredness and weakness 

Serious Side Effects 

• Abdominal pain, bloating, or swelling  
• Blurred vision or vision changes  
• Cough and shortness of breath  
• Increased pain or growth of tumour  
• Numbness or tingling of the skin  
• Pain or feeling of pressure in the pelvis  
• Severe nausea or vomiting 

Cautions 

• Blood clots: Nolvadex D may increase the risk of developing blood clots. This risk is higher in patients with a history of blood clots or certain clotting disorders. Inform your doctor if you have a history of blood clots or if you are experiencing symptoms such as swelling, redness, or pain in the legs. 
• Drug interactions: Nolvadex D may interact with other medications, including certain antidepressants, blood thinners, and hormonal therapies. Inform your doctor about all the medications you are taking to avoid potential interactions. 
• Endometrial cancer: There is a potential increased risk of developing endometrial (uterine) cancer with Nolvadex D. Report any abnormal vaginal bleeding or pelvic pain to your doctor. 
• Eye problems: Rarely, Nolvadex D may cause vision changes or other eye problems. If you experience any changes in your vision, notify your doctor. 
• Liver problems: Nolvadex D may cause liver problems, although this is rare. Notify your doctor if you experience symptoms such as yellowing of the skin or eyes, dark urine, or persistent nausea. 
• Pregnancy: Nolvadex D is classified as Pregnancy Category D, which means it may harm an unborn baby. It should not be used during pregnancy, and effective birth control should be used while taking the medication. 
• Side effects: Nolvadex D can cause various side effects, including hot flashes, vaginal dryness, nausea, and mood changes. Discuss any bothersome side effects with your doctor.