Rythmol ER (Propafenone ER) Medication

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Generic Alternative - Rythmol ER (Propafenone ER)

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Drug Description


Rythmol SR is the extended-release formulation of propafenone hydrochloride. Rythmol SR is indicated for prolonging the time to recurrence of symptomatic atrial fibrillation (AF) in patients with episodic AF.  

Rythmol ER contains an active ingredient called Propafenone. Propafenone belongs to a class of medications known as antiarrhythmics. It works by blocking certain electrical signals in the heart, helping to restore and maintain a normal heart rhythm. Specifically, it blocks sodium channels in the heart muscle cells, which helps to slow down the electrical impulses and stabilize the heart’s rhythm.  

Use and Dosage 

Rythmol ER is usually taken orally by mouth with or without food as directed by your doctor, usually every 12 hours. Swallow the extended-release capsules whole with a glass of water. Do not crush, chew, or break the capsules, as this can interfere with the extended-release mechanism. The tablet can be taken with or without food. However, taking it with a meal or snack may help reduce stomach upset or gastrointestinal side effects. 

Take Rythmol ER at the same time(s) each day, as directed by your healthcare provider. The medication is typically taken every 12 hours, but the exact dosing schedule may vary depending on your individual needs. Do not stop taking the medication abruptly without consulting your healthcare provider, as this can lead to a recurrence of symptoms or other complications. 

If you miss a dose of Rythmol ER, take it as soon as you remember. However, if it is close to the time of your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed dose. 

Side Effects 

Common Side Effects 

  • Anxiety 
  • Change in taste 
  • Chest pain 
  • Constipation 
  • Dizziness 
  • Excess fluid under the skin (edema) 
  • Fatigue 
  • Nausea 
  • Nose or throat infection, including the flu 
  • Palpitations (fast or irregular heartbeats) 
  • Shortness of breath 

Serious Side Effects 

  • Anxiety 
  • Bloating 
  • Blood in urine 
  • Blurred vision 
  • Bruising 
  • Depression 
  • Diarrhea 
  • Dry mouth 
  • Headache 
  • Heart murmur 
  • Low blood pressure 
  • Shaking (tremor) 
  • Sleepiness 
  • Weakness 
  • Wheezing or abnormal lung sounds 


  • Side effects: Like any medication, Rythmol SR can cause side effects. Common side effects may include dizziness, headache, nausea, constipation, and tiredness. Report any unusual or severe side effects to your healthcare provider. 
  • Heart rhythm disturbances: Rythmol SR is used to treat irregular heartbeats, but it can also affect the heart’s electrical activity. Monitor your heart rhythm while taking Rythmol SR and report any irregularities or worsening symptoms to your doctor. 
  • Drug interactions: Rythmol SR may interact with other medications, including certain antidepressants, anticoagulants, beta blockers, and calcium channel blockers. Inform your healthcare provider about all the medications you are taking to avoid potential interactions. 
  • Liver or kidney problems: Rythmol SR is primarily metabolized in the liver and excreted by the kidneys. If you have liver or kidney problems, your healthcare provider may need to adjust the dosage or monitor you more closely while taking Rythmol SR. 
  • Pregnancy and breastfeeding: The safety of Rythmol SR during pregnancy or breastfeeding has not been established. Discuss the potential risks and benefits with your healthcare provider if you are pregnant or breastfeeding.  

Additional information

Generic name:

Propafenone ER


ER 12H Capsule



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