Indications 

Zaditen syrup is an anti-inflammatory medicine used to treat atopic asthma in children. The syrup form allows for easy administration, especially for young children who may have difficulty swallowing tablets. It contains the active ingredient ketotifen, which is an anti-inflammatory medicine. It works by blocking the allergic response and reducing inflammation in the body.  

Ketotifen is an antihistamine, which means it blocks the effects of histamine. Histamine is a chemical released by the immune system in response to an allergic reaction. It causes symptoms such as itching, sneezing, watery eyes, and runny nose. By blocking the effects of histamine, ketotifen helps to relieve these symptoms. 

Use and Dosage 

Zaditen syrup should be taken orally by mouth with or without food. Use the provided measuring device to accurately measure the prescribed dose. Shake the bottle well before each use. The usual recommended dose for Zaditen syrup is twice daily (every 12 hours). However, the specific dosing schedule may vary depending on the individual’s condition. Follow the instructions provided by your healthcare provider. 

Zaditen syrup is typically used for short-term treatment of symptoms. The duration of treatment may vary depending on the individual’s response to the medication and the underlying condition. 

Use the syrup exactly as prescribed by your doctor. If you miss giving your child a dose, give it as soon as possible and continue with the regular dosing schedule. If it is almost time for your child’s next dose, skip the missed dose and continue with the regular dosing schedule. Do not give your child a double dose to make up for the missed one.  

Side Effects 

Common Side Effects  

• Drowsiness 
• Dry mouth 
• Feeling excited 
• Increased appetite 
• Irritability 
• Nervousness 
• Sleep disturbances (trouble sleeping) 
• Slight dizziness 
• Weight gain 

Serious Side Effects 

• A rash combined with fever or discomfort 
• A rash covering a large area of the body 
• A rash that spreads quickly 
• Abdominal pain 
• Bleeding gums 
• Blood in urine 
• Body ache 
• Bruising 
• Burning sensation when urinating 
• Cloudy or red urine 
• Cough 
• Coughing blood 
• Dark urine 
• Diarrhea 
• Difficulty breathing 
• Fatigue 
• Fever 
• Frequent need to urinate at night 
• Headache 
• Increased need to urinate 
• Loss of appetite 
• Nausea 
• Nosebleeds 
• Pain in the pelvis or lower back 
• Pale stools 
• Peeling 
• Puffy eyelid(s) 
• Seizures 
• Signs of a severe skin reaction such as blistering 
• Skin rashes and itching 
• Sore throat 
• Sudden lack of energy 
• Unusual nosebleeds 
• Vomiting 
• Weight loss 
• Yellowing of the skin or whites of the eyes 

Cautions 

• Ketotifen Ophthalmic: Ketotifen fumarate is also available as an ophthalmic solution (eye drops) under the brand name Zaditor. Follow the specific instructions for use when using the eye drops, as they may have different cautions and side effects compared to the syrup form. 
• Proper Use in Children: Ketotifen syrup has been tested in children and, in effective doses, has not been shown to cause different side effects or problems. However, use caution and follow the recommended dosage for children. 
• Sedative Effect: Zaditen syrup may cause drowsiness or sedation in some individuals. Exercise caution when operating machinery, driving, or engaging in activities that require alertness until you know how the medication affects you. Avoid consuming alcohol or taking other medications that can enhance the sedative effect. 
• Dizziness and Impaired Coordination: Zaditen syrup may cause dizziness and impair coordination in some individuals. Be cautious when performing tasks that require balance and coordination to prevent accidents or falls. 
• Pregnancy and Breastfeeding: The safety of Zaditen syrup during pregnancy and breastfeeding has not been established. Consult with a healthcare provider before using the syrup if you are pregnant, planning to become pregnant, or breastfeeding. 
• Liver or Kidney Impairment: Individuals with liver or kidney impairment may require caution when using Zaditen syrup. Dose adjustments or special monitoring may be necessary in these cases. Consult with a healthcare provider for guidance specific to your condition. 
• Allergic Conditions: Zaditen syrup is primarily used to manage allergic conditions. However, it may not be suitable for all types of allergies or may require caution in certain allergic conditions. Consult with a healthcare provider for guidance on the appropriate use of Zaditen syrup for your specific allergic condition. 
• Discontinuation: Consult with a healthcare provider before discontinuing Zaditen syrup. Abruptly stopping the medication may lead to a recurrence of symptoms or withdrawal effects. Your healthcare provider can provide guidance on how to safely discontinue the medication if necessary.