Zilactin B Gel (Benzocaine - non Rx) Medication


Zilactin B Gel (Benzocaine - non Rx)

Prescription Prescription Not Required
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Drug Description


Zilactin B Gel is indicated for the temporary alleviation of pain caused by canker sores, dentures, braces, minor mouth sores, and gum irritations. 

As a local anesthetic, Zilactin B Gel works by numbing the affected area and forming a protective bio adhesive barrier to promote healing. This allows for pain-free eating and drinking for up to 6 hours. 

Uses and Dosage 

Carefully read and adhere to the instructions provided on Zilactin B Gel packaging. If this medication has been prescribed by your doctor, use it as instructed. Should you have any inquiries, do not hesitate to consult your doctor or pharmacist. 

Zilactin B Gel is for oral use only, refrain from contact with the eyes. 

Typically, this medication is applied to the affected areas of the mouth as needed up to 4 times daily. 

To properly apply Zilactin B Gel: 

  1. Dry the affected area. 
  2. Apply a thin layer of gel using a cotton swab or clean finger. 
  3. Allow the gel to dry for 30-60 seconds. 

Avoid excessive use or more frequent application of Zilactin B Gel than directed, as it may elevate the risk of serious side effects. 

Do not peel off the protective film, as attempting to do so may cause skin irritation or tenderness. To remove the film, apply an additional coat of Zilactin B Gel, and promptly wipe the area with a moist gauze pad or tissue. 

Discontinue the use of this medication and inform your doctor if a severe sore throat persists for over 2 days, or if symptoms of a sore mouth last more than 7 days.  

Seek medical attention immediately if you experience fever, headache, rash, swelling, nausea, or vomiting, as these could indicate a potentially serious medical issue requiring alternative treatment.  

If your condition persists, worsens, or you suspect a serious medical problem, seek prompt medical assistance. 

Side Effects 

Common Side Effects 

  • Mild burning, tingling, or stinging sensations  

Inform your doctor promptly if any of these common side effects continue or intensify. 

Zilactin B Gel has been associated with a rare but potentially fatal blood disorder known as methemoglobinemia. The risk is higher for individuals with respiratory issues, specific blood conditions, or those who smoke. Symptoms may manifest within minutes to a few hours of using the gel. Cease use immediately and seek medical assistance if you experience any signs of methemoglobinemia, such as: 

  • Pale/bluish/gray skin 
  • Unusual fatigue 
  • Shortness of breath 
  • Rapid heartbeat 
  • Dizziness 
  • Headache 
  • Confusion 

Allergic Reactions 

Seek immediate medical attention if you experience symptoms of an allergic response to Zilactin B Gel, such as: 

  • Rash 
  • Itching or swelling (especially of the face/tongue/throat) 
  • Severe dizziness 
  • Trouble breathing 

This list does not cover all potential side effects of Zilactin B Gel. Notify your doctor of any additional side effects that may occur. 


Talk to your doctor before using Zilactin B Gel if you have any known allergies, especially to benzocaine, other “caine” anesthetics (e.g., procaine), or any of the inactive ingredients in Zilactin B Gel. 

Consult your doctor if Zilactin B Gel is suitable for you if you have a history of other medical conditions, particularly: 

  • Cardiovascular conditions 
  • Certain blood disorders (G6PD deficiency, pyruvate kinase deficiency, hemoglobin-M disease, NADH-methemoglobin reductase deficiency) 
  • Respiratory issues (e.g., asthma, bronchitis, emphysema) 
  • History of smoking 

Talk to your doctor before using Zilactin B Gel if you are taking other medications, including prescriptions, over-the-counter medicines, vitamins, and herbal supplements, to lower any potential drug interaction. 

Zilactin B Gel should only be used during pregnancy when essential. Have a conversation with your doctor to weigh the potential risks and benefits. 

The transfer of benzocaine into breast milk is uncertain. Seek advice from your healthcare provider before breastfeeding when using this gel. 

Zilactin B Gel is flammable and should be kept clear of open flames or sources of ignition. 

Additional information

Generic name:

Benzocaine – non Rx





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Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Zilactin B Gel (Benzocaine - non Rx). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Zilactin B Gel (Benzocaine - non Rx).