Zostrix HP (Capsaicin - non Rx) Medication


Zostrix HP (Capsaicin - non Rx)

Prescription Prescription Not Required
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Zostrix HP is indicated for the temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, strains, and sprains. 

As a topical analgesic, Zostrix HP works by affecting skin nerve cells connected to pain, leading to diminished nerve cell activity and a decreased perception of pain. 

Uses and Dosage 

Zostrix HP is intended for topical use only. Avoid applying it to wounds or areas with damaged or irritated skin. 

Adhere to the instructions provided on the product packaging and read thoroughly the accompanying patient information leaflet or medication guide. Do not hesitate to consult your doctor or pharmacist if you have any questions. 

Typically, Zostrix HP is applied to the affected skin area 3 to 4 times daily. 

To properly apply the cream: 

  1. Wash hands before applying the cream. 
    •  You may consider using a cotton ball, swab, or latex glove to apply the cream to prevent contact with your hands. 
  2. Apply a thin layer of cream to the affected area and gently massage it in until completely absorbed. 
  3. If the treated area is in your hands, allow a minimum of 30 minutes before washing them after applying the medication. Otherwise, promptly wash your hands with soap and water after use. 

Refrain from applying Zostrix HP to sensitive areas such as the eyes, mouth, nostrils, or genitals. In case of accidental exposure in these regions, flush generously with water.  

Avoid using this cream right before or after activities like bathing, swimming, sunbathing, or vigorous exercise.  

Refrain from bandaging or wrapping the treated area or using a heating pad on it, as these actions could heighten the potential for side effects. 

Use Zostrix HP regularly at the same times every day for maximum effectiveness. 

Inform your healthcare provider if your condition persists beyond 7 days, worsens, or recurs. Seek immediate medical assistance if you suspect a serious medical issue. 

Side Effects 

Listed below are the potential adverse effects of Zostrix HP. Promptly tell your doctor if any of these symptoms persist or worsen. 

Common Side Effects 

  • Warmth, stinging, or a burning sensation at the application site 

Serious Side Effects 

  • Blistering or swelling at the application site 
  • Heightened or unusual pain in the application site 

Discontinue Zostrix HP and promptly notify your healthcare provider if you experience any of the severe side effects above. 

Allergic Reactions 

In rare cases, Zostrix HP may trigger a serious allergic response. Immediate medical assistance must be sought if you observe any indications of an allergic reaction, such as: 

  • Rash 
  • Itching/swelling, particularly of the face, tongue, and throat 
  • Severe dizziness 
  • Trouble breathing 

This list does not encompass all potential side effects of Zostrix HP. Inform your doctor if any unlisted side effects appear. 


Before using Zostrix HP, consult your healthcare provider if you have allergies to capsaicin, zucapsaicin, or hot peppers (Capsicum family). 

Ask your pharmacist for more details about this Zostrix HP, as it may contain inactive ingredients that may cause allergic reactions or other complications. 

Maintain a record of all products you utilize, including prescription/nonprescription medications and herbal supplements, and provide this information to your healthcare provider and pharmacist. Do not initiate, discontinue, or alter medication dosages without your doctor’s authorization. 

Before using Zostrix HP or other local anesthetics, inform your doctor or pharmacist if you are taking class I antiarrhythmic drugs like mexiletine or quinidine. 

Capsaicin closely resembles zucapsaicin. Refrain from using medications that contain zucapsaicin while using Zostrix HP. 

Exposure to dried Zostrix HP residue may lead to coughing, sneezing, watery eyes, or throat irritation. Exercise caution to prevent inhalation of the residue. 

Zostrix HP should only be used during pregnancy if absolutely necessary. Consult your doctor to weigh the risks and benefits before using this product. 

The transfer of capsaicin into breast milk remains uncertain. Seek advice from your healthcare professional prior to breastfeeding. 

Additional information

Generic name:

Capsaicin – non Rx





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Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Zostrix HP (Capsaicin - non Rx). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Zostrix HP (Capsaicin - non Rx).