Indications 

Acular is an ophthalmic solution prescribed to treat post-operative inflammation after cataract surgery.  

Acular is also prescribed to provide short-term relief for ocular itching caused by seasonal allergic conjunctivitis (SAC). 

As a nonsteroidal anti-inflammatory drug (NSAID), Acular exerts its analgesic, anti-inflammatory, and antipyretic effects by inhibiting prostaglandin biosynthesis, a natural hormone responsible for causing pain and inflammation in the body. 

Uses and Dosage 

Before using Acular, and with each prescription refill, carefully read its medication guide and patient information leaflet. For any questions or clarifications, consult your physician or pharmacist without hesitation. 

The frequency of Acular administration varies depending on the condition being treated: 

• For the relief of ocular itching due to SAC, one drop four times a day to the affected eye(s) is usually recommended. 
• For treating post-operative inflammation in patients who have undergone cataract surgery, one drop is typically applied to the affected eye four times daily, starting 24 hours after the surgery and continuing for the first two weeks of the post-operative period. 

To apply Acular, follow these steps: 

• Wash your hands before applying the drops 
• Do not touch the dropper tip or allow it to come in contact with your eye or any surface to prevent contamination 
• Tilt your head back and pull down your lower eyelid to create a pouch 
• Place a single drop of Acular directly into the eye pouch 
• Close your eyes gently for 1-2 minutes and apply slight pressure to the corner of the eye near the nose to prevent drainage 
• Avoid blinking or rubbing your eye 
• Repeat the same steps for the other eye if needed 
• After each use, replace the dropper cap. Rinsing the dropper tip is not necessary 

When using different eye medications (e.g., drops, ointments), wait for 5 minutes before applying the other medication. Administer eye drops prior to ointments to allow proper absorption. 

Use Acular regularly, exactly as prescribed. Do not exceed or reduce the specified number of drops and avoid taking it more frequently or longer than your doctor instructed. 

Side Effects 

Listed below are the potential side effects of Acular. Tell your physician immediately if any of them persist or worsen. 

Common Side Effects 

• Mild eye pain, stinging, or redness 
• Blurred vision 
• Watery eyes 
• Swollen or puffy eyelids 
• Headache 

 Serious Side Effects 

• Severe burning, stinging, or itching of the eyes 
• Non-healing wound in the eye 
• Eye pain, redness, or watering 
• Changes in vision 
• Increased light sensitivity 
• White patches on the eyes 
• Crusting or discharge from the eyes 

Call your doctor right away if you experience any of the severe symptoms listed above. 

Allergic Reactions 

Acular rarely causes severe allergic reactions. However, seek prompt medical assistance if you notice signs of a serious allergic reaction, such as: 

• Rash 
• Itching or swelling, especially of the throat, tongue, or mouth 
• Severe dizziness 
• Trouble breathing 

The adverse effects of Acular listed here are not comprehensive. If you experience any other side effects not included above, inform your doctor right away. 

Cautions 

Before starting treatment with Acular, tell your doctor or pharmacist if you have any known allergies, especially to: 

• Ketorolac 
• Aspirin 
• Other NSAIDs such as celecox and ibuprofen 
• Any medicines 
• Any ingredients present in Acular solution  

To ensure Acular is safe for you, disclose to your physician your medical background, specifically regarding any history of: 

• Asthma, especially if there has been a breathing deterioration after taking aspirin or other NSAIDs 
• Bleeding disorders  
• Previous eye surgeries 
• Eye-related problems like corneal problems or dry eye syndrome 
• Diabetes 
• Rheumatoid arthritis 
• Nasal polyps 

Many drugs may interact with Acular, including prednisone and corticosteroid eye drops. To reduce the risk of drug interactions, tell your healthcare provider about all your current medications, including prescription and over-the-counter drugs, vitamins, and herbal products. 

Acular can increase the risk of bleeding when used together with other drugs that have a similar effect, including anti-platelet drugs like clopidogrel and blood thinners like dabigatran, enoxaparin, and warfarin. Be sure to tell your doctor and pharmacist if you take any of the above medications. 

Carefully check all your medicine labels, as many contain pain relievers/fever reducers (such as aspirin or NSAIDs). These drugs are similar to Acular and may increase the risk of side effects if taken together. 

Continue taking low-dose aspirin if your doctor has directed you to prevent a heart attack or stroke (usually 81-162 milligrams a day) unless instructed otherwise. 

Temporary blurredness or unstable vision may occur after applying Acular. Avoid activities requiring clear vision such as driving or using machinery until it is safe. 

Consider the potential risks to the fetus before using Acular during pregnancy. Notify your doctor if you are pregnant, as it’s unknown whether this medication can cause harm to an unborn baby. 

The transfer of ketorolac on breast milk and its effect on nursing infants is unknown. Consult with your doctor if you are breastfeeding.