Alrex (Loteprednol Etabonate) Medication


Alrex (Loteprednol Etabonate)

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Drug Description


Alrex is an ophthalmic suspension indicated for the temporary reduction of ocular redness, itching, and swelling caused by seasonal allergies. 

Classified as a corticosteroid, Alrex exerts its therapeutic effects by inhibiting the secretion of specific endogenous compounds that induce inflammation, itching, and pain. 

Uses and Dosage 

Before using Alrex and with each prescription refill, carefully read its medication guide and patient information leaflet. If you have any questions or concerns, ask your doctor or pharmacist. 

The usual recommended dosage of Alrex involves instilling one drop into the affected eye(s) four times daily. 

Before applying the eye drops, wash your hands thoroughly with soap and water.  

To use Alrex eye drops: 

  1. Shake the bottle well and check the dropper tip for any damage. Do not touch the dropper tip or allow it to touch your eye or any other surface to avoid contamination. 
  2. Tilt your head back and pull down the lower lid to create a pocket. 
  3. Hold the dropper close to the eye without touching it. 
  4. Squeeze the dropper to release a single drop into the pocket, then remove your finger. 
  5. Close your eye for 2-3 minutes (try not to blink or squeeze your eyelids) and apply gentle pressure to the tear duct. 
  6. Wipe away any excess liquid. 
  7. If you must administer more than one drop in the same eye, wait at least 5 minutes before instilling the subsequent drop. 
  8. Replace and tighten the cap on the dropper bottle. 
  9. Wash hands to remove any medication. 

When using other eye medications, wait at least 5-10 minutes before applying them. Apply eye drops before eye ointments to allow the drops to enter the eye effectively. 

Use Alrex regularly, exactly as prescribed by your doctor, around the same time(s) daily. Avoid using more or less of it or more frequently than instructed. 

Keep using Alrex for the entire duration prescribed, and do not discontinue use without consulting a doctor. Abruptly stopping this medication may exacerbate certain conditions; dosage may need to be gradually reduced under medical supervision. 

Side Effects 

Listed below are the side effects associated with the use of Alrex. If any of these side effects persist or worsen, promptly inform your doctor. 

Common Side Effects 

  • Minor burning sensation when using the eye drops 
  • Eye pain 
  • Blurred vision 
  • Dry or watery eyes 
  • Feeling like something is in the eye 
  • Increased sensitivity to light 
  • Headache 
  • Runny nose 
  • Sore throat 

Serious Side Effects 

  • Pain while using eye drops 
  • Redness or itching getting worse 
  • Eye pain or swelling 
  • Difficulty in closing the eye 
  • Pain behind the eyes 
  • Sudden changes in vision 
  • Tunnel vision 
  • Seeing halos around lights 
  • Redness 
  • Severe discomfort 
  • Crusting or discharge from the eye 

Tell your doctor immediately if you experience any of the serious symptoms mentioned above. 

Allergic Reactions 

Alrex rarely causes severe allergic reactions. However, emergency medical help should be sought if you experience the following indication of an allergic reaction: 

  • Rash 
  • Itching or swelling, especially of the throat, tongue, and face 
  • Severe dizziness 
  • Trouble breathing 

This list does not contain all the potential side effects of Alrex. Notify your doctor promptly if any unlisted effects occur. 


Before using Alrex, apprise your doctor or pharmacist if you have any known allergies, especially to loteprednol, any medications, or any ingredients present in Alrex solution. 

To ensure Alrex is safe for you, disclose to your physician your medical background, specifically regarding any history of: 

  • Cataracts 
  • Eye infections 
  • Recent eye surgery 
  • Myopia (severe nearsightedness) 
  • Open-angle glaucoma 
  • Diabetes 

Many products may interact with Alrex. To lower the risk of drug interactions, disclose to your physician and pharmacist all the medications you currently use, including prescription and non-prescription drugs, dietary supplements, and herbal products. 

Alrex contains benzalkonium chloride, which soft contact lenses can absorb. If your doctor allows you to wear contact lenses, remove them before instilling the eye drops and wait for at least 10 to 15 minutes before reinserting them.  

The administration of Alrex during pregnancy is recommended only if the expected advantages outweigh the possible hazards to the developing fetus. 

Loteprednol’s transfer into breast milk is uncertain. Seek guidance from your doctor before breastfeeding. 

Additional information

Generic name:

Loteprednol Etabonate


Eye Drops



Quantities Available:

5mL, 10mL

Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Alrex (Loteprednol Etabonate). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Alrex (Loteprednol Etabonate).