Atopica (Cyclosporine) Medication


Atopica (Cyclosporine)

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Drug Description


Atopica is a prescription drug limited to veterinary use and should only be administered or prescribed by a licensed veterinarian to manage atopic dermatitis (skin allergies) in dogs weighing 4 lbs. (1.8 kg) or more. 

As an immunosuppressive medication, Atopica exerts its therapeutic effect through the suppression of T-helper and T-suppressor cells, in addition to the inhibition of interleukin-2. This mechanism of action leads to a reduction in inflammation and amelioration of symptoms associated with allergic reactions and immune-mediated conditions in dogs. 

Uses and Dosage 

Before administering Atopica to your dogs and with each prescription refill, carefully read its medication guide and information leaflet. Do not hesitate to seek counsel from your veterinarian for any questions or concerns. 

Atopica is intended for canine use only and is not suitable for human consumption. Ensure that this medication is kept out of the reach of children. 

Atopica’s dosage may vary depending on the dog’s weight. Typically, it is administered at an initial dose of 5 mg/kg/day (3.3-6.7 mg/kg/day) once daily for 30 days. 

After the initial treatment period, the dosing frequency can be gradually reduced to maintain the desired therapeutic effect, starting every other day or twice weekly until the minimum effective frequency is reached. 

This medication should be administered to your dog at least one hour prior to or two hours after a meal. Do not break or open capsules; wearing gloves during administration is recommended. 

After administration, wash your hands thoroughly. If accidental ingestion occurs, seek immediate medical attention, and provide the package insert or label to the physician. 

Side Effects 

Listed below are the side effects associated with the use of Atopica. If any of them persist or worsen, inform your veterinarian promptly. 

Common Side Effects 

  • Vomiting 
  • Diarrhea 

Serious Side Effects 

  • Persistent otitis externa (swimmer’s ear) 
  • Urinary tract infections 
  • Anorexia 
  • Gingival hyperplasia (overgrowth of gums) 
  • Lymphadenopathy (swelling of lymph nodes) 
  • Lethargy 

This list does not contain all the potential side effects of Atopica. If you observe other effects not listed above, inform your veterinarian promptly.  


Before administering Atopica to your dog, notify your veterinarian of any allergies your dog may have, particularly to cyclosporine. 

To ensure Atopica is safe for your dog, inform your veterinarian of any relevant medical history, particularly if your dog has a history of neoplasia.  

Atopica can increase susceptibility to infection and neoplasia development. 

Caution should be exercised when administering Atopica to dogs with diabetes mellitus as it may increase serum glucose levels. If symptoms of diabetes mellitus appear after Atopica use, reducing or stopping the dose should be considered. 

Exercise caution when administering Atopica with drugs that impact the P-450 enzyme system. Concurrent use of Atopica with P-450 enzyme system suppressors, such as azoles (e.g., ketoconazole), may result in elevated plasma levels of cyclosporine. 

Atopica is not intended for breeding dogs or pregnant or lactating bitches. 

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Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Atopica (Cyclosporine). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Atopica (Cyclosporine).