Indications 

Banzel is a prescription medicine utilized in conjunction with other medications for the treatment of seizures associated with Lennox-Gastaut Syndrome (LGS) in both adult and pediatric patients of at least one year of age. 

Banzel belongs to the anticonvulsant class of drugs and is believed to exert its action on the brain’s sodium channels, which transport excessive electrical charges that may trigger seizures. 

Uses and Dosage 

Before taking Banzel and with each prescription refill, thoroughly review its medication guide and patient information leaflet. Seek the guidance of your physician or pharmacist for any questions or concerns. 

The dosage of Banzel is individualized based on the patient’s medical condition, age, response to treatment, and weight in pediatric patients. A low dose is initially prescribed by the doctor, gradually increasing as the patient adapts to the medication.  

Typically, Banzel is taken twice a day with food as prescribed by the doctor. Tablets can be ingested whole, split at the score line, or crushed. 

For maximum efficacy, take Banzel regularly at consistent times each day, as it works optimally when its concentration in the body is stable. It is best ingested at evenly spaced intervals throughout the day and night to ensure a constant level of medication in the body. 

Do not discontinue Banzel without consulting your doctor, even if you feel better. Abruptly discontinuing this medication may exacerbate seizures; your doctor will likely gradually decrease your dosage. 

Inform your doctor if your condition does not improve or deteriorate. 

Side Effects 

Listed below are the side effects associated with the use of Banzel. If any of them persist or worsen, inform your doctor promptly. 

Common Side Effects 

• Headache 
• Dizziness 
• Drowsiness 
• Nausea 
• Feeling tired 

Serious Side Effects 

• Difficulty with balance or coordination 
• Problems with walking 
• Increased or worsening seizures 

Call your doctor immediately if you experience any of the serious symptoms mentioned above. 

Inform your doctor of any new or worsening symptoms, including: 

• Mood or behavioral changes 
• Depression, anxiety, panic attacks, or trouble sleeping 
• Impulsive, agitated, hostile, or aggressive feelings 
• Restlessness, irritability, hyperactivity, or talkativeness 
• Thoughts of suicide or self-harm 

Seek medical treatment immediately if you experience a severe drug reaction affecting multiple body parts. Symptoms may include: 

• Skin rash 
• Fever 
• Swollen glands 
• Muscle aches 
• Severe weakness 
• Unusual bruising 
• Yellowing of the skin or eyes 

Allergic Reactions 

In rare cases, Banzel may cause a severe allergic reaction. Seek immediate medical attention if you experience symptoms such as: 

• Hives 
• Difficult breathing 
• Face, lips, tongue, or throat swelling 

This list does not contain all the potential side effects of Banzel. If you experience any other side effects not mentioned above, notify your doctor. 

Cautions 

Before taking Banzel, inform your doctor and pharmacist if you have any known hypersensitivities, especially to rufinamide, other medicines, or any ingredients present in Banzel tablets. 

To ensure Banzel is safe for you, disclose to your physician your medical background, specifically regarding any history of: 

• A family history of a specific heart condition (QT shortening in the EKG) 
• Kidney disease 
• Liver disease 
• Mental or mood disorders (e.g., depression, suicidal thoughts) 

Orlistat and valproate are among the products that may interact with Banzel. To prevent such drug interactions, inform your doctor and pharmacist about all medications, including prescription and over-the-counter drugs, dietary supplements, and herbal products that you are currently taking. 

Review the labels of all your medications, including allergy or cough-and-cold products, as they may contain drowsiness-inducing ingredients. Consult your pharmacist regarding the safe usage of such products. 

Be sure to tell your doctor or pharmacist if you are consuming other substances that induce drowsiness, such as: 

• Alcohol 
• Marijuana (cannabis) 
• Antihistamines (e.g. cetirizine, diphenhydramine) 
• Sleep or anxiety medications (e.g., diazepam, triazolam, zolpidem) 
• Muscle relaxants 
• Opioid pain relievers (e.g., codeine) 

Refrain from engaging in hazardous activities, including driving or operating heavy machinery, until you have ascertained the impact of Banzel on your cognitive and motor abilities. This medication may impede your thinking and psychomotor functions. 

Banzel can lower the effectiveness of hormonal birth control (birth control pills, injections, implants, skin patches, and vaginal rings), leading to an increased risk of pregnancy. Speak to your doctor or pharmacist about using additional reliable birth control methods. Contact your doctor if you experience new spotting or breakthrough bleeding, as it may indicate a lack of effectiveness of your birth control. 

The use of Banzel during pregnancy should be limited to essential situations. Consult your doctor to weigh the potential risks and benefits. 

The transfer of rufinamide into breast milk is uncertain. Seek advice from your physician before initiating breastfeeding when taking this medication.