Bepreve (Bepotastine Besilate) Medication


Bepreve (Bepotastine Besilate)

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Drug Description


Bepreve is an ophthalmic medication prescribed to alleviate itching from allergic conjunctivitis, a condition that causes itchy, swollen, red, and watery eyes in response to specific airborne substances. 

Classified as an antihistamine, Bepreve exerts its therapeutic effect by impeding the action and release of histamine – a biological compound that elicits allergic symptoms within the body. 

Uses and Dosage 

Before using Bepreve and with each prescription refill, thoroughly review its medication guide and patient information leaflet. Seek the guidance of your doctor or pharmacist for any questions or clarifications. 

Bepreve usage while wearing contact lenses should be avoided due to the possibility of discoloration caused by the preservative in the eye solution. Wait for at least 10 minutes after application before inserting contact lenses. 

The usual dosage for Bepreve involves instilling one drop into the affected eye(s) twice daily. For consistent results, apply this ophthalmic solution at the same time each day. 

To properly use Bepreve, follow these steps: 

  1. Begin by thoroughly washing your hands with soap and water. 
  2. Check the dropper tip to ensure that it is not damaged or broken. 
  3. Keep the dropper and eye drops clean, avoiding contact with the eye or any other surface. 
  4. Tilt your head back and use your index finger to pull down the lower lid of your eye, creating a pocket. 
  5. With the dropper held close to the eye but not touching, use your other hand to brace the remaining fingers against your face for stability. 
  6. Look up and gently squeeze the dropper to release a single drop into the pocket formed by the lower eyelid. Remove your index finger from the lid. 
  7. Close your eye for 2 to 3 minutes and tilt your head down as if looking at the floor. Avoid blinking or squeezing your eyelids. 
  8. Apply gentle pressure on the tear duct using a finger. 
  9. Wipe off any excess liquid on your face with a tissue. 
  10. Wait at least 5 minutes before instilling another drop in the same eye. 
  11. Replace and tightly close the dropper bottle cap. Do not rinse or wipe the dropper tip. 
  12. Wash your hands to remove any residue of the medication. 

Use Bepreve strictly according to your doctor’s instructions. Do not exceed the prescribed dosage or frequency of use without consulting your doctor. 

Inform your doctor if your condition fails to improve within a few days or deteriorates. 

Side Effects 

Although serious side effects are uncommon, Bepreve may cause some common side effects, which include: 

  • Mild eye irritation 
  • Stuffy nose 
  • Sore throat 
  • Headache 
  • Unusual or unpleasant taste in the mouth 

If any of these effects persist or worsen, tell your doctor promptly. 

Discontinue using Bepreve and promptly contact your doctor if you experience severe eye irritation. 

Allergic Reactions 

In rare cases, Bepreve may cause a severe allergic reaction. Seek immediate medical attention if you experience symptoms such as: 

  • Rash 
  • Itching or swelling (especially of the face/tongue/throat) 
  • Dizziness 
  • Trouble breathing 

This list does not contain all the potential side effects of Bepreve. If you experience any other side effects not mentioned above, notify your doctor. 


Before using Bepreve, inform your doctor and pharmacist if you have any known hypersensitivities, especially to bepotastine, other medicines, or any ingredients present in Bepreve solution. 

Before using this ophthalmic solution, inform your doctor or pharmacist of your medical history, particularly if you use contact lenses. 

Topical eye medications such as Bepreve are typically unaffected by concomitant drug use. Nevertheless, various drugs may interact with one another. Ensure that all your healthcare providers are informed of any prescription and over-the-counter medications, vitamins, and herbal products you are taking. 

In case of a new eye infection or injury, or if you need to undergo eye surgery, consult your doctor about whether you should continue using the current bottle of Bepreve or switch to a new one. 

Using Bepreve may cause temporary instability in your vision. Avoid driving, operating machinery, or engaging in any activity that demands clear vision until you are confident that you can do so safely. 

Pregnant women should only use Bepreve when clearly needed. Discuss the risks and benefits of this medication prior to use. 

The transfer of bepotastine into breast milk is uncertain. Seek advice from your doctor before initiating breastfeeding when using these eye drops. 

Additional information

Generic name:

Bepotastine Besilate


Opthalmic Solution



Quantities Available:

5mL, 10mL, 15mL

Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Bepreve (Bepotastine Besilate). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Bepreve (Bepotastine Besilate).