Depakote (Divalproex) Medication


Depakote (Divalproex)

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Generic Alternative - Depakote (Divalproex )

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Drug Description:

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The manufacturer of Depakote is Mylan Pharmaceutical.


Depakote is a medication that treats different types of seizure disorder by affecting certain body chemicals that cause seizures. Depakote can also treat other illnesses such as the manic phase of bipolar disorder (Manic depressive illness). Migraine headaches can also be prevented by using Depakote.


Depakote should be stored away from light, heat, and moisture; and at room temperature.


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Depakote belongs to the class of drugs known as anticonvulsants. Depakote and generic divalproex are used to manage and prevent certain types of seizures. Depakote may be used on its own or in combination with other anticonvulsant medications and has also been used in patients over the age of 18 to treat manic episodes. Depakote affects chemicals in the body that are believed to cause seizures.

Some common side effects of Depakote include mild drowsiness, mild weakness, diarrhea, constipation, stomach upset, depression, anxiety, changes in menstruation, enlarged breasts, tremor, hair loss, weight changes, vision changes, or unpleasant taste in the mouth.
Some serious side effects of Depakote include weakness with vomiting and confusion or fainting, blood in the urine,


Even if you start to feel better, do not stop taking Depakote as it can have negative consequences. Ensure that your prescription is refilled before your current one runs out. If you think that the medication is not working, contact your doctor. Also, be sure to carry an ID card or medical bracelets that indicate that you are on Depakote so that medical professionals can assess your situation in an emergency.


Do not drink alcohol while taking Depakote. Also, Depakote may reduce your reaction speed and impair your thinking. While taking depakote, avoid exposure to artificial UV rays or sunlight as Depakote makes your skin more sensitive; use sun screen.

Patient Family Info:

Follow your doctor’s instructions and the prescription closely. Avoid taking larger doses than recommended. While taking Depakote, be sure to drink lots of water to keep your fluids up. Have your liver tested regularly and schedule regular visits with your doctor. Do not chew or crush the capsules; swallow them whole.

Contra Indication:

Avoid taking Depakote if you have liver disease or a urea cycle disorder. Also, do not take Depakote if you are breast feeding, pregnant, or planning to become pregnant.

Severe Side Effects:

Serious Depakote side effects include (Seek medical attention): unexplained weakness with vomiting and confusion or fainting; easy bruising or bleeding, blood in your urine; fever, sore throat, and headache with a severe blistering, peeling, and red skin

Common Side Effects:

Less serious Depakote side effects include: mild drowsiness or weakness; diarrhea, constipation, upset stomach; depression, anxiety, or other emotional changes; changes in your menstrual periods; enlarged breasts; tremor (shaking); hair loss; weight changes; vision changes; or unusual or unpleasant taste in your mouth.

Other Side Effects:

If you experience, nausea, stomach pain, vomiting, loss of appetite, low fever, dark urine, clay colored stool, yellow skin, yellow eyes then you may have liver damage; seek medical attention immediately. Also call your doctor immediately if you have mood changes, behavior changes, anxiety, depression, hostile, restless, hyperactive, or suicidal.

Additional information

Generic name:

Divalproex, Divalproex Sodium DR


Delayed Release Tablet, Delayed Release Tablet (Enteric Coated)


125mg, 250mg, 500mg

Quantities Available:

90, 100

Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Depakote (Divalproex). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Depakote (Divalproex).