Elmiron (Pentosan Polysulfate) Medication


Elmiron (Pentosan Polysulfate)

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Generic Alternative - Elmiron (Pentosan Polysulfate)

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Drug Description:

Buy Elmiron Online (Pentosan Polysulfate – Generic Alternative)

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Elmiron is used to treat interstitial cystitis and works by acting like a natural body substance in the wall of the bladder. Elmiron and generic pentosan polysulfate works like an anticoagulant that prevents the formation of blood clots and its exact mechanism in the maintenance and treatment of interstitial cystitis is not entirely understood. However, Elmiron helps to reduce bladder inflammation and irritation. The recommended dose is Elmiron 100mg taken three times daily.

Some common side effects of Elmiron include hair loss, nausea, diarrhea, stomach pain, headache, mild dizziness, depressed mood, or mild skin rash.
Some serious side effects of Elmiron include nosebleed, blood in the urine or stools, rectal bleeding, coughing up blood, bleeding gums, or faintness.

Pentosan polysulfate, the generic product is not produced by the same company that makes the brand drug (Elmiron).

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Elmiron is a bladder pain medication used to treat and relieve pain or discomfort associated with interstitial cystitis. Interstitial cystitis is a chronic condition causing bladder pressure, bladder pain, and sometimes pelvic pain, which ranges from mild discomfort to severe pain. This condition is part of a spectrum of diseases known as painful bladder syndrome.

Interstitial cystitis may be caused by damage to the protective lining of the bladder. Irritating substances may inflame the exposed bladder wall. Elmiron appears to work by adhering to the bladder wall to create a buffer against irritating substances and relieve bladder pain.

Dosage and Administration:

The dose of Elmiron prescribed will vary depending on the individual being treated. It is important to follow all your healthcare provider’s instructions and read packaging labels carefully to ensure the best results during your treatment.

The recommended dosage of Elmiron is one capsule (100 mg) 3 times per day.

  • Take Elmiron with water 1 hour before meals or 2 hours after meals.
  • Swallow capsules whole, do not crush or chew

It may take up to 3-6 months for symptoms of your condition to improve.  Since symptom improvement may be gradual, do not stop taking Elmiron or reduce your dosage just because you are feeling better or because Elmiron is not working right away. Talk to your healthcare provider if your symptoms do not improve within 6 months of treatment.

Side Effects:

Elmiron may cause some side effects to develop while helping prevent irritation in your bladder. Speak with your healthcare provider for more information relating to any symptoms that you may experience when taking Elmiron.

The most common side effects associated with Elmiron include:

  • Hair loss
  • Diarrhea
  • Nausea
  • Stomach pain
  • Upset stomach
  • Headache
  • Rash
  • Abnormal liver function tests
  • Dizziness

Serious Side Effects

Some more serious adverse reactions may occur when taking Elmiron. Stop using Elmiron and contact your healthcare provider if you develop any of the following side effects:

  • Changes in the retina of the eye (difficulty reading, vision takes longer to adjust to low or reduced light, blurred vision)
  • Increased bleeding (bruising easily, nosebleeds, bleeding gums, bloody stool)

You may have an increased risk of bleeding while taking Elmiron if you also take the following medicines:

  • Warfarin
  • High doses of aspirin
  • Heparin
  • Anti-inflammatory medications such as ibuprofen

Allergic Reactions

Do not take Elmiron if you are allergic to pentosan polysulfate or any of the other listed capsule ingredients. If you notice signs of an allergic reaction, stop using this bladder medication and contact your healthcare provider.

Warnings and Precautions:

Consult with your healthcare provider if you are planning to undergo surgery, as he/she may advise you to stop taking Elmiron before having any surgery. .

It is important to tell your healthcare provider if you:

  • Have a personal or family history of eye problems of the retina
  • Have a history of aneurysms
  • Have problems with bleeding easily Have gastrointestinal issues (ulcers, polyps, or diverticula)
  • Have liver problems
  • Are pregnant or plan to become pregnant
  • Are breastfeeding or plan to breastfeed

Elmiron has weak anti-coagulant properties which could cause an increase in bleeding and make it easier for you to bleed. This is especially true if the medication is taken with others that also increases your risk of bleeding.

Some drugs have the potential to interact with Elmiron and cause adverse reactions. Tell your healthcare provider about all medications you take, especially those listed previously that can increase your bleeding risk, and any over-the- counter medications.

Form and Strength:

Elmiron is available as a 100-mg capsule.


What causes interstitial cystitis?

Interstitial cystitis may be caused by a breakdown of the protective lining of the bladder, which may allow potentially irritating solutes (a substance dissolved in a solution) in the urine to reach the cells of the bladder wall.

How long does it take for Elmiron to work?

Elmiron uses pentosan polysulfate sodium to create a barrier in the mucous membrane of your bladder to relieve and prevent pain from interstitial cystitis. The active ingredient in Elmiron creates a barrier in your bladder, which may take some time to build up.  Some users have reported a gradual improvement in symptoms within 3 months of treatment, but Elmiron may take up to 6 months to provide full effects.

How common is hair loss with Elmiron?

Hair loss (alopecia) is a side effect that is commonly reported from those using Elmiron. In studies, hair loss started within the first 4 weeks after participants began taking Elmiron. Ninety-seven percent (97%) of the hair loss occurred in a single area of the scalp. The hair loss is reversible once you stop taking this medication.


  1. https://www.orthoelmiron.com/elmiron-for-ic.html#how-may-work
  2. https://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/ELMIRON-pi.pdf
  3. https://www.mayoclinic.org/diseases-conditions/interstitial-cystitis/symptoms-causes/syc-20354357
  4. https://www.goodrx.com/elmiron/what-is

Additional information

Generic name:

Pentosan Polysulfate





Quantities Available:

90, 100, 200, 300

Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Elmiron (Pentosan Polysulfate). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Elmiron (Pentosan Polysulfate).