Isopto Atropine Eye Drops (Atropine Sulfate Eye Drops) Medication


Isopto Atropine Eye Drops (Atropine Sulfate Eye Drops)

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Drug Description


Isopto Atropine Eye Drops are indicated for use before eye examinations and to treat certain eye conditions.  

This eye drop may be used for dilation of the pupils (mydriasis), paralysis of the ciliary muscle of the eye (cycloplegia), and penalization of the healthy eye in the treatment of lazy eye (amblyopia). 

As an anticholinergic medication, Isopto Atropine Eye Drops make pupils bigger by stopping the usual muscle tightening in the eye. This helps the other muscles to tighten and expand the pupil. Moreover, it causes the eye muscles to relax, making it harder to focus on objects. 

Uses and Dosage 

Read the provided medication guide and patient information leaflet for Isopto Atropine Eye Drops before initial use and with each prescription refill. Consult your doctor or pharmacist for any queries or additional information needed. 

The typical dosage and administration of Isopto Atropine Eye Drops are as follows. Always follow your doctor’s instructions precisely if they differ: 

  • For individuals aged 3 months and older: Apply 1 drop into the conjunctival cul-de-sac 40 minutes before the desired maximum dilation time. 
  • For individuals aged 3 years and older: Doses can be repeated up to twice daily, if necessary. 

To properly apply this eye drop, follow these steps: 

  1. Thoroughly wash your hands with soap and water before application. 
    • Avoid touching the dropper tip or letting it touch your eye or any surfaces to prevent contamination. 
  2. Tilt your head back and use your index finger to pull down your lower eyelid, creating a pocket. 
  3. Look up and position the dropper directly over your eye, then gently exert pressure on the dropper to release a single drop into the pocket created by the lower eyelid. 
    •  Remove your index finger. 
  4. Close your eyes for 2 to 3 minutes and tilt your head downward as if looking at the floor.  
    • Try to avoid blinking or squeezing your eyelids. 
  5. Apply gentle pressure to the tear duct area with a finger for 2-3 minutes. 
  6. Use a tissue to wipe away any excess liquid from your face. 
  7. If multiple drops are needed in the same eye, wait at least 5 minutes before applying the next drop. 
  8. Replace and securely close the cap on the dropper bottle.  
    • Do not wipe or rinse the dropper tip. 
  9. Wash your hands to remove any remaining medication. 

To maximize the effectiveness of Isopto Atropine Eye Drops, adhere to a consistent dosing schedule and avoid skipping any doses. Set reminders to apply it at around the same time each day.  

Complete the full prescribed duration of use of this medication. Do not stop treatment without consulting your doctor. 

Side Effects 

Common Side Effects 

  • Mild stinging or discomfort upon applying the drops to the eye 
  • Dryness in the mouth, eyes, nose, or throat 
  • Increased heart rate and blood pressure 
  • Red, irritated, or watery eyes 
  • Drowsiness 
  • Vision issues 

If any of the side effects above continue or worsen, immediately notify your doctor. 

Serious Side Effects 

  • Intense burning or stinging sensation in the eyes 
  • Severe eye redness or irritation 
  • Rapid heart rate, restlessness, or irritability 
  • Signs of eye infection: swelling, redness, severe discomfort, crusting, or drainage 
  • Flushing (sudden warmth, redness, or a tingling sensation) 
  • High blood pressure symptoms:  
    • Severe headache 
    • Blurred vision 
    • Pounding in the neck or ears 

Contact your doctor immediately if any of the above-listed serious side effects occur. 

Allergic Reactions 

Although rare, a severe allergic reaction to Isopto Atripone Eye Drops can occur. Seek immediate medical help if you notice symptoms such as: 

  • Hives 
  • Face, tongue, or throat swelling 
  • Difficulty in breathing 

This list does not include all potential side effects of Isopto Atropine Eye Drops. Inform your healthcare provider should you experience any unlisted effects. 


Before starting treatment with Isopto Atropine Eye Drops, inform your doctor if you have any known allergies, particularly to atropine, belladonna alkaloids (e.g., hyoscyamine, scopolamine), or any of the ingredients in this eye solution. 

Disclose your medical background to your doctor before using Isopto Atropine Eye Drops to assess the appropriateness for your condition, particularly if you have a history of: 

  • Glaucoma (specifically angle-closure type) in oneself or family 
  • Down’s syndrome 
  • Brain damage or spastic paralysis in children 

Inform your doctor about all your medications, including prescriptions and nonprescription medicines, vitamins, and herbal supplements, to mitigate the risk of drug interaction with Isopto Atropine Eye Drops. 

The use of Isopto Atropine Eye Drops may lead to blurred vision and affect your reflexes. Refrain from driving, especially at night, or engaging in hazardous activities until you understand how this medication affects you. 

Isopto Atropine Eye Drops can heighten sensitivity to light in your eyes. Use sunglasses outdoors or in bright light to safeguard your eyes. 

Do not permit unsupervised use of Isopto Atropine by young children, as they may be more susceptible to its side effects. Ensure the medication does not come into contact with the child’s mouth. 

Consider the use of Isopto Atropine Eye Drops during pregnancy only if absolutely necessary. Engage in a discussion with your doctor to evaluate this eye medication’s potential risks and advantages. 

The transfer of atropine into breast milk remains uncertain. Seek advice from your doctor before breastfeeding when using Isopto Atropine Eye Drops. 

Additional information

Generic name:

Atropine Sulfate Eye Drops


Ophthalmic Solution



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Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Isopto Atropine Eye Drops (Atropine Sulfate Eye Drops). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Isopto Atropine Eye Drops (Atropine Sulfate Eye Drops).