Murine Tears (Polyvinyl alcohol/povidone/tetrahydrozoline - non Rx) Medication


Murine Tears (Polyvinyl alcohol/povidone/tetrahydrozoline - non Rx)

Prescription Prescription Not Required
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Murine Tears are indicated to temporarily relieve eye irritation caused by dryness, provide soothing relief from minor eye irritations, and remove redness from the eye. 

Murine Tears is comprised of three active components: tetrahydrozoline,  

polyvinyl alcohol and povidone. 

Tetrahydrozoline is a sympathomimetic amine that works by temporarily constricting the blood vessels in the eye, while polyvinyl alcohol and povidone are lubricants that help protect the eyes from further irritation and dryness. 

Uses and Dosage 

Before using Murin Tears for the first time and every time you get a refill, carefully review the instructions on the product package. For any inquiries, consult a doctor or pharmacist. 

Typically, 1 to 2 drops of Murine Tears are applied in the affected eye(s) up to four times daily as needed or as prescribed by your doctor if this medication is recommended. 

Before use, visually examine the liquid and avoid using it if there is a change in color or it appears cloudy. Dispose of it safely, away from children and pets, and obtain a replacement. 

Prevent contamination by not touching the dropper tip or letting the tip touch the eye or other surfaces. 

For proper application of Murine Tears, follow these steps: 

  1. Wash your hands before applying the eye drops. 
  2. Tilt your head back, look upward, and pull down the lower eyelid to create a pouch. 
  3. Directly position the dropper over the eye and administer 1 drop into the pouch. 
  4. Look downward, gently close your eye, and apply pressure to the inside corner for 1 to 2 minutes to retain the medication inside the eye. 
  5. Repeat steps 2 to 4 if your dose involves more than 1 drop and for the other eye if directed. 
  6. Do not rinse the dropper. Securely replace the dropper cap after each use. 
  7. Wash your hands after each application of the eye drops. 

For best outcomes, use Murine Tears precisely as instructed on the product packaging or as prescribed by your doctor. 

Avoid using this medication for more than 3 to 4 consecutive days, as prolonged use may lead to heightened eye redness (rebound effect when the drug wears off). If such an occurrence arises, consult your doctor. 

If your condition persists or worsens beyond 72 hours, or if you suspect a serious medical issue, discontinue the use of Murine Tears, and seek immediate medical assistance. 

Side Effects 

Common Side Effects 

  • Eye stinging or redness 
  • Dilated pupils 
  • Blurred vision 

Inform your healthcare provider if any of these common side effects persist or become more severe. 

Serious Side Effects 

  • Eye pain 
  • Increased redness, itching, or swelling in or around the eyes 
  • Other vision problems 
  • Tremor (shakiness) 
  • Fast, pounding, or irregular heartbeat 
  • Headache 
  • Sweating 
  • Weakness 
  • Nervousness 

Inform your healthcare provider immediately if any of these serious side effects occur. 

Allergic Reactions 

In rare cases, Murine Tears can cause severe allergic reactions. If you experience symptoms of a serious allergic reaction, seek medical assistance promptly. Signs may include: 

  • Rash 
  • Itching or swelling, particularly of the face, tongue, or throat 
  • Severe dizziness 
  • Difficulty breathing 

This list does not include all potential side effects of Murine Tears. If you notice any effects that are not listed here, inform your doctor. 


Before using Murine Tears, consult a medical professional if you have any known allergies, particularly to polyvinyl alcohol, povidone, tetrahydrozoline, or any inactive ingredients in this eye drop. 

Consult a medical professional before using Murine Tears if you have other medical issues such as: 

  • Glaucoma 
  • Heart problems (e.g., heart attack, chest pain) 
  • High blood pressure 
  • Diabetes 
  • Eye infection or injury 
  • Overactive thyroid (hyperthyroidism) 

Prior to using Murine Tears, seek advice from a healthcare provider if you are currently using any other eye medications or taking prescriptions, over-the-counter drugs, vitamins, or herbal supplements to reduce the risk of potential drug interactions. 

Temporary blurring of vision may occur after using Murine Tears. Refrain from operating vehicles, machinery, or engaging in activities requiring clear vision until it is safe to do so. 

Consult your doctor before using Murine Tears if you are pregnant or breastfeeding to assess the potential benefits and risks of the medication to you and the baby. 

Additional information

Generic name:

Polyvinyl alcohol/povidone/tetrahydrozoline – non Rx




0.5/ 0.6/0.05%

Quantities Available:


Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Murine Tears (Polyvinyl alcohol/povidone/tetrahydrozoline - non Rx). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Murine Tears (Polyvinyl alcohol/povidone/tetrahydrozoline - non Rx).