Visine Allergy (Naphazoline/pheniramine maleate - non Rx) Medication


Visine Allergy (Naphazoline/pheniramine maleate - non Rx)

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Drug Description


Visine Allergy is indicated for the temporary relief of itchy, red eyes triggered by pollen, ragweed, grass, or animal hair and dander. 

Visine Allergy utilizes two active ingredients: naphazoline and pheniramine maleate.  

Naphazoline falls under the category of sympathomimetic amines and works as a decongestant by temporarily narrowing the eye’s blood vessels. On the other hand, pheniramine, an antihistamine, works by blocking histamines, the natural substances that trigger allergic reactions. 

Uses and Dosage 

Before using Visine Allergy and every time you get a refill, carefully review its medication guide and patient information leaflet. For questions or concerns, do not hesitate to consult with your healthcare provider or pharmacist. 

Typically, 1 to 2 drops of Visine Allergy are instilled in the affected eye(s) up to 4 times daily. 

Prior to applying, visually examine the eye drops. If there is any alteration in color or cloudiness, do not use them. Dispose of the medication securely, away from children and pets. 

Refrain from touching or allowing the dropper tip to touch your eye to minimize the risk of infection and potential severe vision impairments. 

To properly use Visine Allergy, follow these steps: 

  1. Tilt your head backward, gaze upward, and pull down the lower eyelid to create a pocket. 
  2. Position the dropper directly above the eye and administer one drop into the pocket made. 
  3. Look downward and gently close your eyes while pressing your finger to the inner corner of the eye for 1 to 2 minutes. This will prevent the medication from draining out. 
  4. Repeat steps 1-3 if your prescribed dose involves more than one drop and follow the same procedure for the other eye if instructed. 
  5. Do not rinse the dropper; securely replace the dropper cap after each use. 

Avoid using Visine Allergy continuously for more than 3 to 4 days. If your condition persists or worsens beyond 72 hours or you suspect a severe medical issue, discontinue use, and seek immediate medical assistance. 

Excessive use of Visine Allergy may lead to heightened eye redness (rebound effect when the drug loses effectiveness). In such cases, inform your healthcare provider. 

Side Effects 

Listed below are the potential adverse effects of Visine Allergy. If any of these symptoms persist or worsen, promptly notify your doctor. 

Common Side Effects 

  • Mild eye burning or stinging 
  • Dilated pupils, blurred vision 
  • Increased sensitivity to light in the eyes 

Serious Side Effects 

  • Persistent or deteriorating eye redness 
  • Eye pain 
  • Alterations in vision 

Stop using Visine Allergy and contact your healthcare provider should you experience any of the serious side effects listed above. 

Allergic Reactions 

In rare instances, Visine Allergy may cause a severe allergic reaction. Promptly seek medical help upon observing any indications of an allergic reaction, including: 

  • Hives 
  • Difficulty breathing 
  • Facial, lips, tongue, or throat swelling 

Not all side effects of Visine Allergy are included in this list. Notify your doctor if any unlisted effects arise. 


Before starting treatment with Visine Allergy, talk to your healthcare provider if you have any known allergies, particularly to naphazoline or pheniramine maleate. 

Inquire with your pharmacist for additional information regarding Visine Allergy, as it may contain inactive ingredients, such as benzalkonium chloride, which could potentially cause allergic reactions or other complications. 

Consult a healthcare professional, such as a doctor or pharmacist, to determine the safety of Visine Allergy if you have any other medical conditions, particularly: 

  • Diabetes 
  • Glaucoma 
  • Heart issues (e.g., heart attack, chest pain) 
  • Hypertension 
  • Eye infection or injury 
  • Hyperthyroidism 
  • Urinary difficulties 

Consult a doctor or pharmacist prior to using Visine Allergy if you are concurrently taking any other medications, including prescription and over-the-counter drugs, as well as vitamins and herbal supplements. Some combinations of medicines can lead to undesired or potentially hazardous effects.  

The potential impact of Visine Allergy on an unborn child is uncertain. If you are pregnant, refrain from using this medication without seeking guidance from a doctor. 

The passage of naphazoline and pheniramine ophthalmic into breast milk and its potential impact on a nursing infant is uncertain. If you are breastfeeding, do not use this medication without consulting a doctor. 

Additional information

Generic name:

Naphazoline/pheniramine maleate – non Rx





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Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Visine Allergy (Naphazoline/pheniramine maleate - non Rx). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Visine Allergy (Naphazoline/pheniramine maleate - non Rx).