Indications 

Voltaren SR is an oral medication used to relieve pain and reduce inflammation caused by conditions such as arthritis, ankylosing spondylitis, and other inflammatory conditions. 

Voltaren SR contains the active ingredient diclofenac sodium. It belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). It works by inhibiting the production of certain chemicals in the body called prostaglandins. These chemicals are involved in the inflammatory process and contribute to pain and swelling. By reducing the production of prostaglandins, Voltaren SR helps to alleviate pain and inflammation. 

Use and Dosage 

Voltaren SR is typically available in tablet and capsules form with strengths of 75 mg and 100 mg. The sustained-release formulation allows for extended release of the medication over time. The tablets are usually taken orally with a glass of water. Swallow the tablet whole without crushing, chewing, or breaking it. Voltaren SR tablets are usually taken once daily, preferably with food, to help minimize the risk of stomach upset.  

The recommended dosage of Voltaren SR (sustained release) tablets can vary depending on the specific condition being treated. However, based on the search results, here are some common dosage recommendations: 

• The recommended initial daily dose of Voltaren SR tablets is 100-150 mg, taken in 1 or 2 divided doses.  
• In milder cases or for long-term therapy, a daily dose of 75-100 mg is usually sufficient.  
• For the relief of osteoarthritis, the recommended dosage is 100-150 mg/day, divided into 2 or 3 doses (e.g., 50 mg twice a day or three times a day).  
• The dosage may be adjusted based on individual response to treatment and the severity of symptoms.  

Continue taking the medication for the prescribed duration, even if your symptoms improve. Do not exceed the recommended dosage or duration of use without consulting with your healthcare provider. 

Side Effects 

Common Side Effects 

• Constipation 
• Diarrhea 
• Dizziness 
• Gas or bloating 
• Headache 
• Ringing in the ears 

Serious Side Effects 

• Back pain 
• Blisters 
• Cloudy, discolored, or bloody urine 
• Difficult or painful urination 
• Difficulty breathing or swallowing 
• Excessive tiredness 
• Fast heartbeat 
• Fever 
• Flu-like symptoms 
• Hives 
• Hoarseness 
• Itching 
• Lack of energy 
• Loss of appetite 
• Nausea 
• Pain in the upper right part of the stomach 
• Pale skin 
• Rash 
• Shortness of breath or difficulty breathing 
• Swelling of the abdomen, feet, ankles, or lower legs 
• Swelling of the eyes, face, tongue, lips, throat, arms, or hands 
• Unexplained weight gain 
• Yellowing of the skin or eyes 

Cautions 

• Cardiovascular risk: Non-steroidal anti-inflammatory drugs (NSAIDs), including diclofenac, may increase the risk of cardiovascular events such as heart attack or stroke. This risk may be higher in individuals with pre-existing cardiovascular conditions or those using high doses for a prolonged duration. 
• Gastrointestinal effects: NSAIDs can increase the risk of gastrointestinal ulcers, bleeding, and perforation, which can be serious or even life-threatening. Individuals with a history of gastrointestinal disorders, such as ulcers or bleeding, may have a higher risk.  
• Kidney effects: NSAIDs, including diclofenac, can cause or worsen kidney problems. This risk may be higher in individuals with pre-existing kidney disease or those taking diuretics or certain blood pressure medications. Regular monitoring of kidney function during treatment with Voltaren SR. 
• Allergic reactions: Some individuals may experience allergic reactions to diclofenac, such as rash, hives, swelling, or difficulty breathing. If you have a known allergy to NSAIDs or have experienced allergic reactions in the past, inform your healthcare provider before starting Voltaren SR. 
• Pregnancy and breastfeeding: Voltaren SR is not recommended during pregnancy, especially in the third trimester. Consult with your healthcare provider for guidance if you are pregnant or breastfeeding. 
• Interactions with other medications: Diclofenac may interact with other medications, including blood thinners, diuretics, antidepressants, and certain heart medications. 
• Hepatic effects: Diclofenac can rarely cause liver damage or liver function abnormalities. Individuals with pre-existing liver disease or a history of liver problems should exercise caution when using Voltaren SR. Regular monitoring of liver function may be necessary. 
• Asthma and respiratory conditions: NSAIDs, including diclofenac, can worsen asthma symptoms or cause respiratory reactions in individuals with underlying respiratory conditions.  
• Skin reactions: Some individuals may experience skin reactions such as rashes, itching, or photosensitivity while using diclofenac. If you develop any skin changes or reactions, discontinue the medication, and seek medical attention. 
• Fluid retention and edema: Diclofenac may cause fluid retention and edema (swelling) in some individuals, especially those with a history of heart failure or high blood pressure. Regular monitoring of blood pressure and signs of fluid retention is important during treatment. 
• Elderly population: Elderly individuals may be at higher risk for adverse effects associated with NSAIDs, including gastrointestinal bleeding, cardiovascular events, and kidney problems. 
• Drug tolerance and dependence: Prolonged use of diclofenac may lead to the development of tolerance or dependence.  
• Surgery and bleeding risk: Diclofenac can increase the risk of bleeding during and after surgery. Inform your healthcare provider if you are scheduled for surgery, as temporary discontinuation of diclofenac may be necessary.