Xopenex HFA (Levalbuterol) Medication


Xopenex HFA (Levalbuterol)

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Generic Alternative - Xopenex HFA (Levalbuterol)

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Xopenex HFA is a prescription medicine indicated for managing or preventing bronchospasms in individuals aged four and above who have reversible obstructive airway conditions like asthma and chronic obstructive pulmonary disease COPD. 

Xopenex HFA is categorized as a bronchodilator, functioning by relaxing the muscles encircling the airways to facilitate easier breathing. 

Uses and Dosage 

Before using Xopenex HFA and with every prescription refill, carefully review the accompanying medication guide and patient information leaflet. Consult your doctor or pharmacist if you have any queries or concerns. 

Typically, Xopenex HFA is inhaled every 4 to 6 hours as needed. 

Before initial use, prime the inhaler device by releasing 4 test sprays away from your face. Shake the inhaler for at least 5 seconds before each spray. Prime again if not used in over 3 days. 

To use the inhaler: 

  1. Remove the cap from the mouthpiece of the actuator and inspect the inside for any foreign objects before use. Ensure that the canister fits well in the actuator. 
  2. Shake the inhaler vigorously for 5 seconds before use. 
  3. Hold the inhaler in an upright position with the mouthpiece facing you. Prior to inserting the mouthpiece into your mouth, exhale through your mouth, expelling as much air from your lungs as possible. 
  4. Place the mouthpiece in your mouth and seal your lips around it. 
  5. While inhaling deeply and slowly, press down on the center of the targeting rings until a spray of medicine is released. Then, release the dose indicator. 
  6. After completing the inhalation, remove the mouthpiece from your mouth. Close your mouth and hold your breath for 10 seconds or as long as comfortable before exhaling gently. 
  7. If two inhalations are prescribed, wait at least 1 minute between them, and repeat steps 2 through 6 for your second dose. 
  8. Promptly replace the cap on the mouthpiece after use, ensuring it securely snaps into place. 

To achieve the best outcomes, follow the precise instructions for Xopenex HFA usage. Avoid exceeding or reducing the prescribed dosage or frequency without your doctor’s guidance. 

To maintain the functionality of the inhaler, clean it weekly by taking out the canister and rinsing the mouthpiece under warm running water for a minimum of 30 seconds. Remove excess water by shaking, and ensure all components are completely air-dried before reassembling the inhaler. 

Store Xopenex HFA with the mouthpiece facing downward at room temperature, away from heat, sunlight, and freezing conditions. Dispose of it when the dose number indicator reaches “0,” indicating that all sprays have been used. 

Side Effects 

Listed below are the potential adverse effects of Xopenex HFA. Inform your doctor if any of these symptoms persist or worsen. 

Common Side Effects 

  • Nervousness 
  • Dizziness 
  • Trembling (tremor) 
  • Difficulty sleeping 
  • Headache 
  • Nausea 
  • Dry mouth 
  • Cough 
  • Sore throat 
  • Runny nose 

Serious Side Effects 

  • Wheezing, choking, or breathing difficulties following Xopenex HFA use 
  • Pounding or fluttering heartbeats 
  • Deteriorating asthma symptoms 
  • Low potassium symptoms:  
  • Leg cramps 
  • Constipation 
  • Irregular heartbeats 
  • Chest fluttering 
  • Excessive thirst 
  • Increased urination 
  • Numbness or tingling 
  • Muscle weakness or limp sensation 

Contact your doctor immediately if you experience any of the severe symptoms above. 

Allergic Reactions 

In rare cases, Xopenex HFA may trigger a serious allergic response. Promptly seek medical attention if you notice signs of an allergic reaction, such as: 

  • Face, lips, tongue, or throat swelling 
  • Difficulty in breathing 
  • Hives 

This list does not encompass all potential side effects of Xopenex HFA. Report to your doctor if you encounter any unlisted side effects. 


Before starting treatment with Xopenex HFA, inform your doctor if you have any known allergies, particularly to levalbuterol or to similar drugs (e.g., albuterol, metaproterenol, salmeterol). 

Ask your pharmacist for more details about this inhaler, as it may contain inactive ingredients that may trigger allergic reactions or other complications. 

To ensure Xopenex HFA is safe for you, disclose to your doctor your medical background, especially if you have a history of: 

  • Heart conditions (e.g., irregular heartbeat, angina, prior heart attack) 
  • Hypertension (high blood pressure) 
  • Kidney disease 
  • Seizures 

To minimize the potential for drug interactions with Xopenex HFA, ensure you inform all healthcare providers about your complete medication regimen, encompassing prescribed and over-the-counter medications, as well as vitamins and herbal supplements. 

Levalbuterol closely resembles albuterol. Avoid the use of inhaled medications containing albuterol when using Xopenex HFA. 

The effects of Xopenax HFA on an unborn child are uncertain. Inform your doctor if you are pregnant or intend to become pregnant to assess its risks and benefits. 

The transfer of levalbuterol inhalation into breast milk and its potential impact on a nursing baby are unknown. Inform your healthcare provider if you are breastfeeding. 

Additional information

Generic name:





45mcg, 50mcg

Quantities Available:

200doses, 400doses, 600doses

Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Xopenex HFA (Levalbuterol). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Xopenex HFA (Levalbuterol).