Indications 

Cambia is classified as a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation in the body by decreasing the production of certain substances.  

Cambia oral powder is specifically intended for adults aged 18 years and above for the treatment of migraine headache attacks, with or without aura.  

This is not used as a preventive measure for migraine headaches, nor to treat cluster headaches.  

Cambia only works to alleviate a headache that has already started and does not prevent headaches or reduce the frequency of attacks. 

Uses and Dosage 

Before taking diclofenac, carefully read the Medication Guide provided by your pharmacist. If you have any doubts, consult your doctor or pharmacist. 

Take this medicine by mouth, exactly as prescribed by your physician. Refrain from increasing the dose on your own in case you do not experience relief, and instead, talk to your doctor. Cambia, as per the manufacturer, must not be taken more than once in case of a migraine attack. 

Empty the contents of one packet into a cup containing 1 to 2 ounces (30 to 60 milliliters) of water, stir well and drink immediately. Do not mix it with any other liquid apart from water. If stomach discomfort occurs, take it with food, milk, or antacids. However, if you take this medication with a high-fat meal, its efficacy might be reduced. 

To minimize the risk of stomach bleeding and other adverse effects, take this medication at the lowest effective dose. Do not exceed the prescribed dose or take it more frequently than prescribed. 

Side Effects 

If you experience adverse reactions to Cambia, a nonsteroidal anti-inflammatory drug used to relieve pain and inflammation, you should seek medical attention immediately. Here are some signs and symptoms that require urgent care: 

Allergic Reactions 

• Hives 
• Difficulty breathing 
• Swelling of the face or throat 

Severe Side Effects

Severe skin reactions:  

• Fever 
• Sore throat 
• Burning eyes 
• Skin pain 
• Red or purple skin rash with blistering and peeling 

Serious drug reactions that can affect multiple body systems require prompt medical treatment. Symptoms of such reactions include: 

• Skin rash 
• Fever 
• Swollen glands 
• Muscle aches 
• Severe weakness 
• Unusual bruising 
• Yellowing of the skin or eyes 

You should call your doctor right away if you experience any of the following while taking Cambia: 

• Skin rash (even if mild) 
• Flu-like symptoms 
• Heart problems:
  • Swelling
  • Rapid weight gain
  • Shortness of breath 
• Kidney problems:
  • Little or no urination
  • Painful or difficult urination
  • Swelling in your arms or legs
  • Fatigue 
• Liver problems:
  • Nausea
  • Diarrhea
  • Stomach pain (upper right side)
  • Tiredness
  • Itching
  • Dark urine
  • Jaundice 
• Signs of stomach bleeding:
  • Bloody or tarry stools
  • Coughing up blood
  • Vomiting that looks like coffee grounds 

Common Side Effects 

• Indigestion, gas, nausea, vomiting, or stomach pain 
• Diarrhea or constipation 
• Headache, dizziness, or drowsiness 
• Abnormal lab tests 
• Itching or sweating 
• Stuffy nose 
• Increased blood pressure 
• Swelling or pain in your arms or legs 

Caution 

Prior to using this prescription medication, provide your healthcare provider with a comprehensive medical history, including a history of asthma, nasal polyps, hypertension, stroke, heart disease, liver problems, blood disorders, and gastrointestinal problems. This is crucial as some of these conditions may significantly affect how your system will react to this medication.  

Disclose any prescription drugs, nonprescription drugs, and herbal products that you are taking, as they may interact with Cambia. 

While on this treatment, monitor for any signs of an allergic reaction. You should not take this oral medication if you have a known allergy to diclofenac, aspirin, other NSAIDs, or any inactive ingredients contained in it. Symptoms of hypersensitivity may include itching, swelling, skin rashes, severe dizziness, and breathing difficulties. In case of such symptoms, you must contact your local medical emergency line. 

When taking NSAIDs, the risk of kidney problems increases, especially if you are dehydrated or have any heart disease. Drink plenty of fluids to prevent dehydration and report any changes in your urine output immediately. 

Alcohol consumption should be avoided or limited while taking this medication, as it can trigger or exacerbate some of its adverse effects, such as drowsiness, dizziness, and stomach bleeding. Caution should be exercised when engaging in activities that require alertness, such as driving and operating machinery. 

Note that this oral solution may contain aspartame. If you have phenylketonuria or any disorder that requires you to avoid or limit aspartame or phenylalanine in your diet, consult your healthcare provider. 

This medication may increase your sensitivity to the sun. Therefore, you should limit your sun exposure and avoid indoor tanning. When going outdoors, apply sunblock cream and wear protective clothing. 

Pregnant women should avoid using this medication due to potential risks to the unborn baby. This medication may pass into breast milk. As always, potential benefits must outweigh potential risks.