Colestid (Colestipol) Medication


Colestid (Colestipol)

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Colestid is a prescribed medication used in conjunction with diet to lower elevated serum total and low-density lipoprotein cholesterol (LDL-C) levels in patients with primary hypercholesterolemia (elevated LDL-C) who have an inadequate response to diet alone. 

Categorized as a bile acid sequestrant drug, Colestid functions by binding bile acids in the intestines to facilitate their elimination from the body. 

Uses and Dosage 

Before taking Colestid and with each prescription refill, thoroughly review its medication guide and patient information leaflet. Ask your physician or pharmacist if you have any questions or concerns. 

The dosage of Colestid is individualized according to the patient’s medical condition and treatment response.  

To minimize the likelihood of adverse effects, physicians usually initiate therapy with a low dose and gradually titrate upward. 

Typically, Colestid is taken once or twice a day as prescribed by the doctor. Tablets must be swallowed whole, not cut, crushed, or chewed.  

Each tablet should be taken individually with an ample amount of liquid, such as water or juice. If you have trouble swallowing the tablet or feel it becomes lodged in your esophagus after swallowing, contact your doctor. 

For optimal results, take Colestid regularly around the same time(s) every day. 

Keep taking this medication even if you feel well, as individuals with high cholesterol often do not experience symptoms. 

Side Effects 

Listed below are the potential adverse effects that may arise from taking Colestid. If any of them last or worsen, inform your physician promptly. 

Common Side Effects 

  • Constipation 
  • Hemorrhoids 

Serious Side Effects 

  • Difficulty swallowing 
  • Severe constipation or stomach pain 
  • Black, bloody, or tarry stools 

Call your doctor immediately if you experience any of the severe side effects listed above. 

Allergic Reactions 

Severe allergic reactions to Colestid are uncommon; however, seek immediate medical attention if you experience symptoms such as: 

  • Hives 
  • Difficulty breathing 
  • Swelling of the face, lips, tongue, or throat 

This list does not contain all the potential side effects of Colestid. If you encounter any unlisted effects, inform your doctor right away. 


Before starting treatment with Colestid, inform your doctor and pharmacist if you have any known hypersensitivities, especially to colestipol, any other medications, or any of the ingredients present in Colestid tablets. 

To ensure Colestid is safe for you, disclose to your physician your medical background, specifically if you have a history of: 

  • Swallowing difficulties 
  • Constipation 
  • Hemorrhoids 
  • Kidney disease 

Colestid may interact with certain products, including: 

  • Blood thinners like warfarin 
  • Mycophenolate 
  • Raloxifene 

To lower the risk of such drug interactions, inform your doctor and pharmacist about all your medicines, including prescription and over-the-counter drugs, other dietary supplements, and herbal products. 

To ensure proper absorption and effectiveness of other medications, avoid taking them simultaneously with Colestid. Take your other medicines at least 1 hour before or 4 hours after taking Colestid. 

To address the potential interference of Colestid with nutrient absorption (including folic acid and fat-soluble vitamins A, D, E, and K), your doctor may recommend a multivitamin supplement. For additional details, consult your doctor. 

Colestid should only be used when necessary during pregnancy. Consult with your doctor to weigh the risks and benefits. 

Colestid may hinder the absorption of essential vitamins crucial for nursing mothers. Inform your doctor if you are breastfeeding before taking this medication. 

Additional information

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Quality Prescription Drugs has provided information from third parties intended to increase awareness and does not contain all the information about Colestid (Colestipol). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Colestid (Colestipol).