Indications 

Fenofibrate is a medication that is prescribed in conjunction with a proper diet to facilitate the reduction of low-density lipoprotein (LDL) and triglycerides while raising high-density lipoprotein (HDL) levels in the bloodstream. Its mechanism of action is based on augmenting the activity of a natural enzyme that catalyzes the breakdown of fats in the blood. As a member of the fibrate class of drugs, fenofibrate can lower the risk of pancreatitis by lowering triglyceride levels in individuals with significantly elevated blood triglyceride concentrations.  

Nevertheless, the efficacy of fenofibrate in reducing the risk of myocardial infarction or stroke remains uncertain. Therefore, patients should discuss the potential risks and benefits of fenofibrate with their healthcare provider. Furthermore, individuals can optimize the therapeutic effects of this medication by adhering to a proper diet, such as a low-fat and low-cholesterol diet, along with adopting healthy lifestyle changes such as exercising, losing weight if overweight, and quitting smoking. Patients should consult their healthcare provider for more detailed information. 

Uses and Dosage 

Administer this medication orally according to your physician’s instructions, usually once per day. Fenofibrate is available in various forms of capsules and tablets that contain different amounts of the medication. Do not alter between various brands or forms of this drug unless advised by your doctor. Some types of this medication should be taken with food, while others may be taken with or without food. Consult your pharmacist about your specific brand of fenofibrate. Taking this medication correctly is crucial to ensure that it has the maximum efficacy. 

The dose of this medication is dependent on your medical condition and response to therapy. If you are taking other drugs that reduce your cholesterol levels, such as bile acid-binding resins like cholestyramine or colestipol, consume fenofibrate at least one hour before or four to six hours after consuming these medicines. These medications may bind to fenofibrate, which can hinder your body from fully absorbing the drug. 

Side Effects 

Seek immediate medical attention if you experience symptoms of an allergic reaction to Tricor, such as:  

• Hives 
• Difficulty breathing 
• Swelling in your face or throat 
• Develop a severe skin reaction, including:  
• A fever 
• Sore throat 
• Burning in your eyes 
• Skin pain 
• Red or purple rash that spreads and causes blistering and peeling 

In rare instances, fenofibrate may induce a medical condition that results in the disintegration of skeletal muscle tissue, potentially leading to kidney failure. If you have unexplained muscle pain, tenderness, or weakness, particularly if accompanied by a fever, unusual tiredness, or dark-colored urine, contact your healthcare provider immediately. 

Cautions 

Prior to taking fenofibrate, inform your healthcare provider or pharmacist of any allergies you have, including hypersensitivity to other fibrates like fenofibric acid, or any other allergies you may have. This medication may contain inactive ingredients, such as soy, that can provoke allergic reactions or other issues. Consult your pharmacist for further information. 

Before using this medication, inform your healthcare provider or pharmacist of your medical history, notably if you have a history of kidney disease, gallbladder disease, liver disease (such as biliary cholangitis, hepatitis), or alcohol use. 

Before undergoing any surgical procedure, inform your healthcare provider or dentist about all the medications and products you use.